{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T03:45:34Z","timestamp":1777952734742,"version":"3.51.4"},"reference-count":29,"publisher":"PAGEPress Publications","license":[{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatol Reports"],"abstract":"<jats:p>Over the last three decades, vitiligo research has expanded across clinical, genetic, and therapeutic domains. Accurate literature retrieval and bibliometric analysis are essential for identifying major themes and emerging topics within this field. A bibliometric analysis was conducted to identify vitiligo-related studies published between 1991 and 2024, using the Science Citation Index Expanded (SCIE) database. Using a \u201cfront page\u201d strategy, articles containing \u201cvitiligo\u201d in the title, abstract, or author keywords were included. Extracted data encompassed titles, abstracts, and keywords to identify dominant research themes. Citation indicators, including total and annual citations, were used to assess impact and trends. Analyses were performed using Microsoft Excel 365. A total of 4,925 vitiligo articles were retrieved and divided into three periods: 1991-2010 (1,654); 2011-2018 (1,541); and 2019-2024 (1,730). The most frequent title word was \u201cpatients\u201d (17%), while abstracts frequently included \u201cpatients\u201d (63%), \u201cskin\u201d (46%), and \u201ctreatment\u201d (41%). Prominent author keywords were \u201cmelanocytes\u201d, \u201cautoimmunity\u201d, and a growing focus on \u201cepidemiology\u201d. Increasing trends appeared for \u201cimmunotherapy\u201d and \u201coxidative stress\u201d, while \u201cefficacy\u201d, \u201cprevalence\u201d, and \u201cpolymorphism\u201d declined. Research is shifting toward molecular mechanisms and innovative therapies, offering guidance for future studies and improved disease understanding and management.<\/jats:p>","DOI":"10.4081\/dr.2026.10656","type":"journal-article","created":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T13:14:48Z","timestamp":1777900488000},"source":"Crossref","is-referenced-by-count":0,"title":["Publication trends in vitiligo research from 1991 to 2024: a comprehensive bibliometric analysis"],"prefix":"10.4081","author":[{"given":"Yuh-Shan","family":"Ho","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hilla","family":"Rosenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Shapiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Horev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2549","published-online":{"date-parts":[[2026,5,4]]},"reference":[{"key":"39790","unstructured":"1. Wang MH, Fu HZ, Ho YS. Comparison of universities\u2019 scientific performance using bibliometric indicators. Malays J Libr Inf Sci 2011;16:1-19."},{"key":"39791","doi-asserted-by":"crossref","unstructured":"2. Ho YS. Letter to the Editor Regarding \u201cGlobal Research Trends in Radiotherapy for Gliomas: A Systematic Bibliometric Analysis\u201d. World Neurosurg 2023;170:251.","DOI":"10.1016\/j.wneu.2022.10.110"},{"key":"39792","doi-asserted-by":"crossref","unstructured":"3. Usman M, Ho YS. COVID-19 and the emerging research trends in environmental studies: a bibliometric evaluation. Environ Sci Pollut Res Int 2021;28:16913-24.","DOI":"10.1007\/s11356-021-13098-z"},{"key":"39793","unstructured":"4. Williams RC. The article\u2019s title. Am J Cardiol 1985."},{"key":"39794","unstructured":"5. Day RA. How to Write and Publish a Scientific Paper. ISI Press; 1979."},{"key":"39795","doi-asserted-by":"crossref","unstructured":"6. Peset F, Garz\u00f3n-Farin\u00f3s F, Gonz\u00e1lez L, et al. Survival analysis of author keywords: An application to the library and information sciences area. J Assoc Inf Sci Technol 2020;71:462-73.","DOI":"10.1002\/asi.24248"},{"key":"39796","unstructured":"7. Garfield E. KeyWords Plus: 1S1\u2019s Breakthrough Retrieval Method. Part 1. Expanding Your Searching Power on Current Contents on Diskette. Essays Inf Sci 1990;13:295-301. Available from: https:\/\/garfield.library.upenn.edu\/essays\/v13p295y1990.pdf"},{"key":"39797","doi-asserted-by":"crossref","unstructured":"8. Wang CC, Ho YS. Research trend of metal-organic frameworks: a bibliometric analysis. Scientometrics 2016;109:481-513.","DOI":"10.1007\/s11192-016-1986-2"},{"key":"39798","doi-asserted-by":"crossref","unstructured":"9. Xie S, Zhang J, Ho YS. Assessment of world aerosol research trends by bibliometric analysis. Scientometrics 2008;77:113-30.","DOI":"10.1007\/s11192-007-1928-0"},{"key":"39799","doi-asserted-by":"crossref","unstructured":"10. Li LL, Ding G, Feng N, et al. Global stem cell research trend: Bibliometric analysis as a tool for mapping of trends from 1991 to 2006. Scientometrics 2009;80:39-58.","DOI":"10.1007\/s11192-008-1939-5"},{"key":"39800","doi-asserted-by":"crossref","unstructured":"11. Mao N, Wang MH, Ho YS. A Bibliometric Study of the Trend in Articles Related to Risk Assessment Published in Science Citation Index. Hum Ecol Risk 2010;16:801-24.","DOI":"10.1080\/10807039.2010.501248"},{"key":"39801","doi-asserted-by":"crossref","unstructured":"12. Zhang G, Xie S, Ho YS. A bibliometric analysis of world volatile organic compounds research trends. Scientometrics 2010;83:477-92.","DOI":"10.1007\/s11192-009-0065-3"},{"key":"39802","doi-asserted-by":"crossref","unstructured":"13. Li Z, Ho YS. Use of citation per publication as an indicator to evaluate contingent valuation research. Scientometrics 2008;75:97-110.","DOI":"10.1007\/s11192-007-1838-1"},{"key":"39803","doi-asserted-by":"crossref","unstructured":"14. Ho Y, F\u00fcl\u00f6p T, Krisanapan P, et al. Artificial intelligence and machine learning trends in kidney care. Am J Med Sci 2024;367:281-95.","DOI":"10.1016\/j.amjms.2024.01.018"},{"key":"39804","doi-asserted-by":"crossref","unstructured":"15. Ho YS, Satoh H, Lin SY. Japanese lung cancer research trends and performance in Science Citation Index. J-STAGE 2010;49:2219-28.","DOI":"10.2169\/internalmedicine.49.3687"},{"key":"39805","unstructured":"16. Li J, Zhang Y, Wang X, Ho Y. Bibliometric Analysis of Atmospheric Simulation Trends in Meteorology and Atmospheric Science Journals. Croatica Chemica Acta 2009;82:695-705"},{"key":"39806","unstructured":"17. Banchereau J, Palucka AK, Dhodapkar M, et al. Immune and clinical responses in patients with m melanoma to CD34(+) progenitor-derived dendritic cell vaccine. Cancer Res 2001;61:6451-8."},{"key":"39807","doi-asserted-by":"crossref","unstructured":"18. Hua C, Boussemart L, Mateus C, et al. Association of Vitiligo With Tumor Response in Patients With Metastatic Melanoma Treated With Pembrolizumab. JAMA Dermatol 2016;152:45.","DOI":"10.1001\/jamadermatol.2015.2707"},{"key":"39808","doi-asserted-by":"crossref","unstructured":"19. Alkhateeb A, Fain PR, Thody A, et al. Epidemiology of Vitiligo and Associated Autoimmune Diseases in Caucasian Probands and Their Families. Pigment Cell Res 2003;16:208-14.","DOI":"10.1034\/j.1600-0749.2003.00032.x"},{"key":"39809","doi-asserted-by":"crossref","unstructured":"20. Alikhan A, Felsten LM, Daly M, Petronic-Rosic V. Vitiligo: A comprehensive overview. J Am Acad Dermatol 2011;65:473-91.","DOI":"10.1016\/j.jaad.2010.11.061"},{"key":"39810","doi-asserted-by":"crossref","unstructured":"21. Tsai TF, Wang TS, Hung ST, et al. Epidemiology and comorbidities of psoriasis patients in a national database in Taiwan. J Dermatol Sci 2011;63:40-6.","DOI":"10.1016\/j.jdermsci.2011.03.002"},{"key":"39811","doi-asserted-by":"crossref","unstructured":"22. Fu HZ, Wang MH, Ho YS. The most frequently cited adsorption research articles in the Science Citation Index (Expanded). J Colloid Interface Sci 2012;379:148-56.","DOI":"10.1016\/j.jcis.2012.04.051"},{"key":"39812","doi-asserted-by":"crossref","unstructured":"23. Rosenberg H, Hollander Y, Gordon CB, et al. Evaluating the Quality of TikTok Videos on Vitiligo: A Cross-Sectional Study. Int J Dermatol 2025;64:2299-305.","DOI":"10.1111\/ijd.17962"},{"key":"39813","doi-asserted-by":"crossref","unstructured":"24. Kr\u00fcger C, Schallreuter K. Stigmatisation, Avoidance Behaviour and Difficulties in Coping are Common Among Adult Patients with Vitiligo. Acta Derm Venereol 2015;95:553-8.","DOI":"10.2340\/00015555-1981"},{"key":"39814","doi-asserted-by":"crossref","unstructured":"25. Katz EL, Harris JE. Translational Research in Vitiligo. Front Immunol 2021;12.","DOI":"10.3389\/fimmu.2021.624517"},{"key":"39815","doi-asserted-by":"crossref","unstructured":"26. Lee JH, Ju HJ, Seo JM, et al. Comorbidities in Patients with Vitiligo: A Systematic Review and Meta-Analysis. J Invest Dermatol 2023;143:777-89.e6.","DOI":"10.1016\/j.jid.2022.10.021"},{"key":"39816","doi-asserted-by":"crossref","unstructured":"27. Spritz RA. Shared Genetic Relationships Underlying Generalized Vitiligo and Autoimmune Thyroid Disease. Thyroid 2010;20:745-54.","DOI":"10.1089\/thy.2010.1643"},{"key":"39817","doi-asserted-by":"crossref","unstructured":"28. Chang WL, Ko CH. The Role of Oxidative Stress in Vitiligo: An Update on Its Pathogenesis and Therapeutic Implications. Cells 2023;12:936.","DOI":"10.3390\/cells12060936"},{"key":"39818","doi-asserted-by":"crossref","unstructured":"29. Failla CM, Carbone ML, Fortes C, et al. Melanoma and Vitiligo: In Good Company. Int J Mol Sci 2019;20:5731.","DOI":"10.3390\/ijms20225731"}],"container-title":["Dermatology Reports"],"original-title":[],"link":[{"URL":"https:\/\/journals.pagepress.net\/dr\/article\/download\/10656\/9928","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.pagepress.net\/dr\/article\/download\/10656\/9928","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T13:14:56Z","timestamp":1777900496000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.pagepress.net\/dr\/article\/view\/10656"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,4]]},"references-count":29,"URL":"https:\/\/doi.org\/10.4081\/dr.2026.10656","relation":{},"ISSN":["2036-7406","2036-7392"],"issn-type":[{"value":"2036-7406","type":"electronic"},{"value":"2036-7392","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5,4]]}}}