{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T09:50:36Z","timestamp":1791280236598,"version":"4.1.0"},"reference-count":0,"publisher":"PAGEPress Publications","license":[{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatol Reports"],"abstract":"<jats:p>Acne vulgaris is a common inflammatory disorder with psychosocial consequences. Data on anxiety and outcomes of intense pulsed light (IPL)-based therapy for moderate-to-severe acne remain limited in Vietnam. This study described clinical characteristics, anxiety burden, satisfaction, and treatment outcomes after IPL-based management.\u00a0A single-center study was conducted at Can Tho Dermatology Hospital (Vietnam) from May 2023 to May 2024. A total of 220 patients aged \u226512 years with moderate-to-severe acne vulgaris were enrolled. Acne severity was evaluated using the Global Acne Grading System (GAGS), while anxiety was assessed using the anxiety subscale of the\u00a0Depression Anxiety Stress Scales-21 (DASS-21). Thirty-six patients with anxiety underwent an 8-week IPL-based combination regimen. Clinical response, GAGS score, anxiety change, satisfaction, and tolerability were evaluated.\u00a0The mean age was 21.8\u00b16.3 years, and 59.5% were female. Papulopustular acne was predominant (98.6%), and all patients had facial involvement. Post-inflammatory hyperpigmentation and atrophic scarring were present in 100.0% and 76.8%, respectively. Baseline anxiety was identified in 48.6% of patients. Severe acne was strongly associated with anxiety compared with moderate acne (odds ratio [OR]=24.64; 95% confidence interval [CI]: 7.32-127.43; p&lt;0.001). In the treatment subgroup, good clinical response increased from 36.1% at week 4 to 66.7% at week 8. Mean GAGS score decreased from 25.3\u00b13.8 to 12.7\u00b15.9 (p&lt;0.001), and treatment success reached 86.1%. Anxiety decreased from 100.0% to 30.6% after treatment (p&lt;0.001). Most patients were satisfied (86.1%), and adverse effects were mild.\u00a0Moderate-to-severe acne was frequently associated with anxiety. An IPL-based regimen was associated with clinical improvement, reduced anxiety, high satisfaction, and good tolerability.<\/jats:p>","DOI":"10.4081\/dr.2026.10943","type":"journal-article","created":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T08:53:06Z","timestamp":1791276786000},"source":"Crossref","is-referenced-by-count":0,"title":["Anxiety, patient satisfaction, and outcomes of intense pulsed light-based treatment for moderate-to-severe acne vulgaris in Southern Vietnam"],"prefix":"10.4081","author":[{"given":"Thi Xuan Tam","family":"Huynh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thi Yen Ba","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuyet Tam","family":"Tu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2549","published-online":{"date-parts":[[2026,10,6]]},"container-title":["Dermatology Reports"],"original-title":[],"link":[{"URL":"https:\/\/journals.pagepress.net\/dr\/article\/download\/10943\/10104","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.pagepress.net\/dr\/article\/download\/10943\/10104","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T08:53:07Z","timestamp":1791276787000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.pagepress.net\/dr\/article\/view\/10943"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,6]]},"references-count":0,"URL":"https:\/\/doi.org\/10.4081\/dr.2026.10943","relation":{},"ISSN":["2036-7406","2036-7392"],"issn-type":[{"value":"2036-7406","type":"electronic"},{"value":"2036-7392","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10,6]]}}}