{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T17:04:19Z","timestamp":1776445459141,"version":"3.51.2"},"reference-count":31,"publisher":"PAGEPress Publications","issue":"3","license":[{"start":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T00:00:00Z","timestamp":1694476800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Transl Myol"],"abstract":"<jats:p>Reports of electromyography during hypoxic exercise are contrasting, due to protocol and muscle diversity. This work aimed to investigate alterations in muscle activation and myoelectrical fatigue during exercise at high-altitude in those muscles primarily involved in trekking. Twelve young adults balanced by gender and age were tested at low (1,667 m) and high (4,554 m, \"Capanna Margherita\", Italy) altitude, during an isometric squat lasting 60 seconds. High-density surface electromyography was performed from the quadriceps of right limb. The root mean square (RMS), median frequency with its slope, and muscle fiber conduction velocity (MFCV) were computed. Neither males nor females showed changes in median frequency (Med: 36.13 vs 35.63 Hz) and its slope (Med: -9 vs -12 degree) in response to high-altitude trekking, despite a great inter-individual heterogeneity, nor differences were found for MFCV. RMS was not significantly equivalent, with greater values at low altitude (0.385 \u00b1 0.104 mV) than high altitude (0.346 \u00b1 0.090 mV). Unexpected results can be due either to a postural compensation of the whole body compensating for a relatively greater effort or to the inability to support muscle activation after repeated physical efforts.\u00a0 Interesting results may emerge by measuring simultaneously electromyography, muscle oxygenation and kinematics comparing trekking at normoxia vs hypoxia.<\/jats:p>","DOI":"10.4081\/ejtm.2023.11637","type":"journal-article","created":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T15:13:21Z","timestamp":1694531601000},"source":"Crossref","is-referenced-by-count":4,"title":["Electromyographic signature of isometric squat in the highest refuge in Europe"],"prefix":"10.4081","volume":"33","author":[{"given":"Riccardo","family":"Rua","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1911-3606","authenticated-orcid":false,"given":"Danilo","family":"Bondi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9170-2977","authenticated-orcid":false,"given":"Carmen","family":"Santangelo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3023-7143","authenticated-orcid":false,"given":"Pamela","family":"Pignatelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7507-1255","authenticated-orcid":false,"given":"Tiziana","family":"Pietrangelo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4557-9127","authenticated-orcid":false,"given":"Stefania","family":"Fulle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vito","family":"Fanelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8343-9024","authenticated-orcid":false,"given":"Vittore","family":"Verratti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2549","published-online":{"date-parts":[[2023,9,12]]},"reference":[{"key":"89647","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.12719"},{"key":"89648","doi-asserted-by":"publisher","DOI":"10.1089\/ham.2008.1104"},{"key":"89649","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-57099-y"},{"key":"89650","doi-asserted-by":"publisher","DOI":"10.3390\/nu13020460"},{"key":"89651","doi-asserted-by":"publisher","DOI":"10.1093\/milmed\/usaa041"},{"key":"89652","doi-asserted-by":"publisher","DOI":"10.3390\/s22114150"},{"key":"89653","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1994.77.6.2840"},{"key":"89654","doi-asserted-by":"publisher","DOI":"10.1016\/j.crphys.2021.09.002"},{"key":"89655","doi-asserted-by":"publisher","DOI":"10.1089\/ham.2014.1027"},{"key":"89656","doi-asserted-by":"publisher","DOI":"10.1111\/apha.13788"},{"key":"89657","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20160"},{"key":"89658","unstructured":"Gerilovsky L, Karadimov D, Ianakiev B. Hypoxia reduces the conduction velocity of the excitation along the striated muscles in man. Electromyogr Clin Neurophysiol. 1991 May-Jul;31(4):203-8. PMID: 1908773."},{"key":"89659","unstructured":"Hendriksen PH, Oey PL, van Veen BK, Wallinga-de Jonge W, Veldman H. Muscle conduction velocity and morphology after prolonged hypoxemia and diabetes in rats. Electromyogr Clin Neurophysiol. 1992 Oct-Nov;32(10-11):491-7. PMID: 1446581."},{"key":"89660","doi-asserted-by":"publisher","DOI":"10.23736\/S0022-4707.23.14859-6"},{"key":"89661","doi-asserted-by":"publisher","DOI":"10.1177\/00315125231165165"},{"key":"89662","doi-asserted-by":"publisher","DOI":"10.22489\/CinC.2022.096"},{"key":"89663","unstructured":"Schommer K, B\u00e4rtsch P. Basic medical advice for travelers to high altitudes. Dtsch Arztebl Int. 2011 Dec;108(49):839-47; quiz 848. Epub 2011 Dec 9. 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