{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T00:54:06Z","timestamp":1790902446706,"version":"4.1.0"},"reference-count":30,"publisher":"PAGEPress Publications","issue":"3","license":[{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Transl Myol"],"abstract":"<jats:p>Diagnosis of Carpal Tunnel Syndrome (CTS) relies on a structured clinical approach with Electrodiagnostic Studies (EDX) accepted as the gold standard in the diagnosis. Yet, Ultrasound (US) has emerged as a non-invasive alternative especially in assessing morphological changes. And so, to accurately diagnose CTS by a valid non-painful simple tool, objectively assess postoperative improvement and finally to predict postoperative clinical outcome from preoperative data; clinical, EDX, and US data were collected, compared and correlated pre- and 1 month postoperative. While US achieved diagnostic accuracy of 80% in CTS diagnosis, particularly Wrist Cross-Sectional Area (wCSA) and Wrist-Forearm Ratio (WFR), it remains less sensitive than EDX. The diagnosis of CTS using wCSA\/WFR achieved a sensitivity of 80.0%\/80.0% and a specificity of 100%\/85.7%, at a cutoff score of 12.5mm2\/2.1 or above. In addition, linear regression analysis showed that only compound motor action potential (CMAP) amplitude could predict postoperative clinical improvement. Sensitivity of EDX (93.33%) overcome that of the US in detection of postoperative improvement. US is less sensitive than EDX in diagnosing CTS, assessment and prediction of postoperative clinical outcome.<\/jats:p>","DOI":"10.4081\/ejtm.2026.15547","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:52:29Z","timestamp":1787755949000},"source":"Crossref","is-referenced-by-count":0,"title":["Ultrasonography versus electrodiagnosis of median nerve before and after open carpal tunnel release surgery: which can better diagnose, predict and assess postoperative improvement?"],"prefix":"10.4081","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2663-7534","authenticated-orcid":true,"given":"FatemaAlZahraa","family":"Ahmad","sequence":"first","affiliation":[{"name":"Clinical Neurophysiology Unit, Faculty of Medicine, Cairo University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-6045-1726","authenticated-orcid":true,"given":"Shahira","family":"Mostafa","sequence":"additional","affiliation":[{"name":"Clinical Neurophysiology Unit, Faculty of Medicine, Cairo University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eman","family":"A. Maher","sequence":"additional","affiliation":[{"name":"Clinical Neurophysiology Unit, Faculty of Medicine, Cairo University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mostafa","family":"Ezzat","sequence":"additional","affiliation":[{"name":"Orthopedic Surgery Department, Faculty of Medicine, Cairo University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aliaa","family":"Ali Tawfeek","sequence":"additional","affiliation":[{"name":"Clinical Neurophysiology Unit, Faculty of Medicine, Cairo University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2549","published-online":{"date-parts":[[2026,8,26]]},"reference":[{"key":"248460","doi-asserted-by":"publisher","DOI":"10.1177\/1558944720919182"},{"key":"248461","doi-asserted-by":"publisher","DOI":"10.5312\/wjo.v14.i1.6"},{"key":"248462","unstructured":"3 American Academy of Orthopaedic Surgeons. 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Comparison of ultrasonic and electrophysiological pre and postoperative evaluation for carpal tunnel syndrome. J Surg 2019;11:1203."},{"key":"248481","doi-asserted-by":"publisher","DOI":"10.1177\/15589447221093677"},{"key":"248482","unstructured":"23 Aksekili MAE, Bi\u00e7ici V, I\u015f\u0131k \u00c7, et al. Comparison of early postoperative electrophysiological and clinical findings following carpal tunnel syndrome. Int J Clin Exp Med 2015;8:10011-6."},{"key":"248483","doi-asserted-by":"publisher","DOI":"10.1016\/j.neucli.2012.02.133"},{"key":"248484","unstructured":"25 Naranjo A, Ojeda S, Ara\u00f1a V, et al. Usefulness of clinical findings, nerve conduction studies and ultrasonography to predict response to surgery in idiopathic carpal tunnel syndrome. Clin Exp Rheumatol 2009;27:786-93."},{"key":"248485","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-14-241"},{"key":"248486","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-021-04771-y"},{"key":"248487","doi-asserted-by":"publisher","DOI":"10.1177\/1558944717703739"},{"key":"248488","doi-asserted-by":"publisher","DOI":"10.1016\/j.cnp.2018.02.005"},{"key":"248489","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-010-1637-5"}],"container-title":["European Journal of Translational Myology"],"original-title":[],"link":[{"URL":"https:\/\/www.pagepressjournals.org\/bam\/article\/download\/15547\/14335","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.pagepressjournals.org\/bam\/article\/download\/15547\/14335","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T00:01:59Z","timestamp":1790899319000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.pagepressjournals.org\/bam\/article\/view\/15547"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,26]]},"references-count":30,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2026,9,30]]}},"URL":"https:\/\/doi.org\/10.4081\/ejtm.2026.15547","relation":{},"ISSN":["2037-7460","2037-7452"],"issn-type":[{"value":"2037-7460","type":"electronic"},{"value":"2037-7452","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8,26]]}}}