{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T00:53:59Z","timestamp":1790902439311,"version":"4.1.0"},"reference-count":37,"publisher":"PAGEPress Publications","issue":"3","license":[{"start":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:00:00Z","timestamp":1790208000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Transl Myol"],"abstract":"<jats:p>Athletes require effective recovery strategies to sustain performance, particularly in high-demand sports. Photobiomodulation (PBM) has emerged as a non-invasive approach capable of supporting muscle function without reported adverse effects. Wearable nanotechnology-based devices, such as Taopatch\u00ae, allow continuous and localized PBM delivery, representing a potential tool for sports applications. This pilot study investigated the acute effects of Taopatch\u00ae on neuromuscular performance in 28 young tennis players (11 females, 17 males; age 14.41 \u00b1 2.60 years). Participants completed Squat Jump (SJ), Counter Movement Jump (CMJ), stiffness, and reaction time assessments before (T1) and after a 15-minute application period (T2). Taopatch\u00ae application was associated with pre\u2013post increases in SJ flight time (unadjusted p=0.042) and maximal pre-take-off velocity (Vmax; unadjusted p=0.012), while CMJ concentric work also increased (unadjusted p=0.014). Several effects remained significant after Benjamini\u2013Hochberg false discovery rate correction, whereas none remained significant after the more conservative Holm\u2013Bonferroni correction. Stiffness responses varied among subgroups, while reaction time remained unchanged. These preliminary findings suggest a potential association between Taopatch\u00ae application and acute changes neuromuscular performance. However, the statistical evidence was sensitive to the multiple-comparison correction applied, and controlled studies are required to confirm these exploratory observations.<\/jats:p>","DOI":"10.4081\/ejtm.2026.16043","type":"journal-article","created":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T12:43:12Z","timestamp":1790253792000},"source":"Crossref","is-referenced-by-count":0,"title":["Preliminary pre-post changes in neuromuscular performance after application of a wearable photobiomodulation device in young tennis athletes"],"prefix":"10.4081","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2832-1960","authenticated-orcid":true,"given":"Alberto","family":"Grossi","sequence":"first","affiliation":[{"name":"Department of Neurosciences, Biomedicine and Movement, University of Verona, Italy, Department of Human Science and Promotion of Quality of Life, San Raffaele University, Rome"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-2054-1811","authenticated-orcid":true,"given":"Andrea","family":"Fabris","sequence":"additional","affiliation":[{"name":"Department of Human Science and Promotion of Quality of Life, San Raffaele University, Rome"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1342-5881","authenticated-orcid":true,"given":"Francesca","family":"Campoli","sequence":"additional","affiliation":[{"name":"Department of Human Science and Promotion of Quality of Life, San Raffaele University, Rome"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucio","family":"Caprioli","sequence":"additional","affiliation":[{"name":"Department of Human Science and Promotion of Quality of Life, San Raffaele University, Rome, Italy; Department of Sports Engineering Lab, \u201cTor Vergata\u201d University, Rome"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Vitarelli","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Biomedicine and Movement, University of Verona, Italy, Department of Human Science and Promotion of Quality of Life, San Raffaele University, Rome"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8223-6671","authenticated-orcid":true,"given":"Donatella","family":"Di Corrado","sequence":"additional","affiliation":[{"name":"Department of Sport Sciences, Kore University, Cittadella Universitaria, Enna"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Messina","sequence":"additional","affiliation":[{"name":"Posturalab Research Institute, Palermo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5207-7558","authenticated-orcid":true,"given":"Domenico","family":"Cherubini","sequence":"additional","affiliation":[{"name":"Facultad de Deporte, Catholic University of Murcia (UCAM), Murcia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Nowak","sequence":"additional","affiliation":[{"name":"Institute of Physical Culture Sciences, University of Szczecin, Poland; Department of Pathology, Pomeranian Medical University in Szczecin, Szczecin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5227-2567","authenticated-orcid":true,"given":"Elvira","family":"Padua","sequence":"additional","affiliation":[{"name":"Department of Human Science and Promotion of Quality of Life, San Raffaele University, Rome"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2774-4950","authenticated-orcid":true,"given":"Giuseppe","family":"Messina","sequence":"additional","affiliation":[{"name":"Department of Human Science and Promotion of Quality of Life, San Raffaele University, Rome, Italy; Posturalab Research Institute, Palermo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Ruscello","sequence":"additional","affiliation":[{"name":"Department of Human Science and Promotion of Quality of Life, San Raffaele University, Rome, Italy; Department of Industrial Engineering, Faculty of Engineering, \u201cTor Vergata\u201d University, Rome, Italy; LUISS SportLab, Rome"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2549","published-online":{"date-parts":[[2026,9,24]]},"reference":[{"key":"253178","doi-asserted-by":"crossref","unstructured":"1. Heiss R, Lutter C, Freiwald J, et al. Advances in delayed-onset muscle soreness (DOMS)\u2014part II: treatment and prevention. Sportverletz Sportschaden 2019;33:21\u20139.","DOI":"10.1055\/a-0810-3516"},{"key":"253179","doi-asserted-by":"crossref","unstructured":"2. Leal-Junior ECP, Lopes-Martins R\u00c1B, Bjordal JM. Clinical and scientific recommendations for the use of photobiomodulation therapy in exercise performance enhancement and post-exercise recovery: current evidence and future directions. Braz J Phys Ther 2019;23:71\u201375.","DOI":"10.1016\/j.bjpt.2018.12.002"},{"key":"253180","doi-asserted-by":"crossref","unstructured":"3. Mandi\u0107 M, Gustafsson T, Lundberg TR. NSAIDs and muscle hypertrophy: methodological concerns and alternative interpretations. J Physiol 2026; doi: 10.1113\/JP290811.","DOI":"10.1113\/JP290811"},{"key":"253181","doi-asserted-by":"crossref","unstructured":"4. Dupuy O, Douzi W, Theurot D, et al. An evidence-based approach for choosing post-exercise recovery techniques to reduce markers of muscle damage, soreness, fatigue, and inflammation: a systematic review with meta-analysis. Front Physiol 2018;9:403.","DOI":"10.3389\/fphys.2018.00403"},{"key":"253182","doi-asserted-by":"crossref","unstructured":"5. Ko GWY, Clarkson C. The effectiveness of acupuncture for pain reduction in delayed-onset muscle soreness: a systematic review. Acupunct Med 2020;38:63\u201374.","DOI":"10.1177\/0964528419887978"},{"key":"253183","doi-asserted-by":"crossref","unstructured":"6. Sirolli S, Guarnera D, Ricotti L, Cafarelli A. Triggerable patches for medical applications. Adv Mater 2024;36:e2310110.","DOI":"10.1002\/adma.202310110"},{"key":"253184","doi-asserted-by":"crossref","unstructured":"7. Benkov AA, Nagornev SN, Frolkov VK, et al. Simultaneous application of transcranial magnetic stimulation and low-frequency electrostatic field as treatment of carbohydrate and lipid disorders in patients with metabolic syndrome. Eur J Transl Myol 2022;32:10351.","DOI":"10.4081\/ejtm.2022.10351"},{"key":"253185","doi-asserted-by":"crossref","unstructured":"8. Leal-Junior ECP. Photobiomodulation therapy in skeletal muscle: from exercise performance to muscular dystrophies. Photomed Laser Surg 2015;33:53\u201354.","DOI":"10.1089\/pho.2015.9851"},{"key":"253186","doi-asserted-by":"crossref","unstructured":"9. Amato A, Messina G, Feka K, et al. Taopatch\u00ae combined with home-based training protocol to prevent sedentary lifestyle and biochemical changes in MS patients during COVID-19 pandemic. Eur J Transl Myol 2021;31:9877.","DOI":"10.4081\/ejtm.2021.9877"},{"key":"253187","doi-asserted-by":"crossref","unstructured":"10. Ferraresi C, Huang YY, Hamblin MR. Photobiomodulation in human muscle tissue: an advantage in sports performance? J Biophotonics 2016;9:1273\u20131299.","DOI":"10.1002\/jbio.201600176"},{"key":"253188","doi-asserted-by":"crossref","unstructured":"11. Leal-Junior ECP, Vanin AA, Miranda EF, et al. Effect of phototherapy (low-level laser therapy and light-emitting diode therapy) on exercise performance and markers of exercise recovery: a systematic review with meta-analysis. Lasers Med Sci 2015;30:925\u2013939.","DOI":"10.1007\/s10103-013-1465-4"},{"key":"253189","doi-asserted-by":"crossref","unstructured":"12. Ailioaie LM, Litscher G. Photobiomodulation and sports: results of a narrative review. Life (Basel) 2021;11:1339.","DOI":"10.3390\/life11121339"},{"key":"253190","doi-asserted-by":"crossref","unstructured":"13. Tumilty S, Munn J, McDonough S, et al. Low level laser treatment of tendinopathy: a systematic review with meta-analysis. 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BMC Musculoskelet Disord 2008;9:75.","DOI":"10.1186\/1471-2474-9-75"},{"key":"253194","doi-asserted-by":"crossref","unstructured":"17. Campoli F, Iovane A, Fabris A, et al. Acute effects of nanotechnological devices for the muscle and joint pain treatment. Eng Methodol Med Sports 2024:86\u201396.","DOI":"10.1007\/978-3-031-63755-1_7"},{"key":"253195","unstructured":"18. Leal-Junior ECP, Lopes-Martins R\u00c1B, Dalan F, Ferrari M, Sbabo FM, Generosi RA, et al. Effect of phototherapy (low-level laser therapy) on exercise-induced skeletal muscle fatigue and biochemical markers of muscle damage: a randomized double-blind placebo-controlled trial. Clin J Sport Med 2010;20:1\u20137."},{"key":"253196","doi-asserted-by":"crossref","unstructured":"19. Luo W, Lee C, Tam K, Huang T. Effects of low-level laser therapy on muscular performance and soreness recovery in athletes: a meta-analysis of randomized controlled trials. Sports Health 2022;14:687\u2013693.","DOI":"10.1177\/19417381211039766"},{"key":"253197","doi-asserted-by":"crossref","unstructured":"20. De Paiva PRV, Tomazoni SS, Machado CDSM, et al. Effects of photobiomodulation therapy combined with static magnetic field on training adaptations and detraining responses: a randomised placebo-controlled trial. BMJ Open Sport Exerc Med 2025;11:e002799.","DOI":"10.1136\/bmjsem-2025-002799"},{"key":"253198","doi-asserted-by":"crossref","unstructured":"21. Guti\u00e9rrez-Men\u00e9ndez A, Rodr\u00edguez-Fern\u00e1ndez L, Zorzo C, et al. Safety of 810 nm photobiomodulation in the developing brain: no evidence of glial reactivity or pro-inflammatory cytokine expression in rats. Lasers Med Sci 2025;40:409.","DOI":"10.1007\/s10103-025-04684-5"},{"key":"253199","doi-asserted-by":"crossref","unstructured":"22. Rodr\u00edguez-Fern\u00e1ndez L, Zorzo C, Arias JL. Photobiomodulation in the aging brain: a systematic review from animal models to humans. GeroScience 2024;46:6583\u20136623.","DOI":"10.1007\/s11357-024-01231-y"},{"key":"253200","doi-asserted-by":"crossref","unstructured":"23. Chamkouri H, Liu Q, Zhang Y, et al. Brain photobiomodulation therapy on neurological and psychological diseases. J Biophotonics 2024;17:e202300145.","DOI":"10.1002\/jbio.202300145"},{"key":"253201","doi-asserted-by":"crossref","unstructured":"24. Vanin AAV, Verhagen E, Barboza SD, et al. Photobiomodulation therapy for the improvement of muscular performance and reduction of muscular fatigue associated with exercise in healthy people: a systematic review and meta-analysis. Lasers Med Sci 2018;33:181\u2013214.","DOI":"10.1007\/s10103-017-2368-6"},{"key":"253202","doi-asserted-by":"crossref","unstructured":"25. Aguirra P, do Nascimento AP, Casonatto J, et al. A systematic review and meta-analysis of the acute effects of photobiomodulation therapy on the maximum number of repetitions in resistance exercise in young adults. Lasers Med Sci 2025;40:184.","DOI":"10.1007\/s10103-025-04441-8"},{"key":"253203","doi-asserted-by":"crossref","unstructured":"26. Boatta A, Pagliaro A, Messina G, et al. Metabolic and neuromuscular responses to high-intensity training with and without Taopatch\u00ae nanotechnology: a pilot randomized control study. Cent Eur J Sport Sci Med 2025;52:57\u201365.","DOI":"10.18276\/cej.2025.4-05"},{"key":"253204","doi-asserted-by":"crossref","unstructured":"27. Carbonari B, Balducci F, Cesaretti G, et al. Performance, balance and posture variations with Occlusal Splint and Taopatch\u00ae devices: a retrospettive cross-over study. J Sports Med Phys Fitness 2021;61:317\u2013323.","DOI":"10.23736\/S0022-4707.20.11053-3"},{"key":"253205","doi-asserted-by":"crossref","unstructured":"28. Machado AF, Leal-Junior ECP, Batista NP, et al. Photobiomodulation therapy applied during an exercise-training program does not promote additional effects in trained individuals: a randomized placebo-controlled trial. Braz J Phys Ther 2022;26:100388.","DOI":"10.1016\/j.bjpt.2021.100388"},{"key":"253206","doi-asserted-by":"crossref","unstructured":"29. Machado AF, Micheletti JK, Vanderlei FM, et al. Effect of low-level laser therapy (LLLT) and light-emitting diodes (LEDT) applied during combined training on performance and post-exercise recovery: protocol for a randomized placebo-controlled trial. Braz J Phys Ther 2017;21:296\u2013304.","DOI":"10.1016\/j.bjpt.2017.05.010"},{"key":"253207","doi-asserted-by":"crossref","unstructured":"30. Ferraresi C, Hamblin MR, Parizotto NA. Low-level laser (light) therapy (LLLT) on muscle tissue: performance, fatigue and repair benefited by the power of light. Photonics Lasers Med 2012;1:267\u2013286.","DOI":"10.1515\/plm-2012-0032"},{"key":"253208","doi-asserted-by":"crossref","unstructured":"31. De Marchi T, Leal-Junior ECP, Bortoli C, et al. Low-level laser therapy (LLLT) in human progressive-intensity running: effects on exercise performance, skeletal muscle status, and oxidative stress. Lasers Med Sci 2012;27:231\u2013236.","DOI":"10.1007\/s10103-011-0955-5"},{"key":"253209","doi-asserted-by":"crossref","unstructured":"32. Hamblin MR. Mechanisms and mitochondrial redox signaling in photobiomodulation. Photochem Photobiol 2018;94:199\u2013212.","DOI":"10.1111\/php.12864"},{"key":"253210","doi-asserted-by":"crossref","unstructured":"33. Chung H, Dai T, Sharma SK, et al. The nuts and bolts of low-level laser (light) therapy. Ann Biomed Eng 2012;40:516\u2013533.","DOI":"10.1007\/s10439-011-0454-7"},{"key":"253211","doi-asserted-by":"crossref","unstructured":"34. Zagatto AM, Dutra YM, Lira FS, et al. Full body photobiomodulation therapy to induce faster muscle recovery in water polo athletes: preliminary results. Photobiomodul Photomed Laser Surg 2020;38:766\u2013772.","DOI":"10.1089\/photob.2020.4803"},{"key":"253212","doi-asserted-by":"crossref","unstructured":"35. Qiu D, He J, Li B, et al. The effect of photobiomodulation therapy on muscle performance in volleyball and football players: a meta-analysis of randomized controlled trials. Sports Health 2026;18:496\u2013506.","DOI":"10.1177\/19417381251372977"},{"key":"253213","doi-asserted-by":"crossref","unstructured":"36. Leal EC, De Godoi V, Mancalossi JL, et al. Comparison between cold water immersion therapy (CWIT) and light-emitting diode therapy (LEDT) in short-term skeletal muscle recovery after high-intensity exercise in athletes\u2014preliminary results. Lasers Med Sci 2011;26:493\u2013501.","DOI":"10.1007\/s10103-010-0866-x"},{"key":"253214","doi-asserted-by":"crossref","unstructured":"37. Padoin S, Zeffa AC, Molina Corr\u00eaa JC, et al. Phototherapy improves muscle recovery and does not impair repeated bout effect in plyometric exercise. 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