{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T02:31:39Z","timestamp":1787797899897,"version":"build-2784847793"},"reference-count":220,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2016,3,21]],"date-time":"2016-03-21T00:00:00Z","timestamp":1458518400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infectious Disease Reports"],"abstract":"<jats:p>Many clinical and laboratory-based studies have been reported for skin rashes which may be due to viral infections, namely pityriasis rosea (PR), Gianotti-Crosti syndrome (GCS), asymmetric periflexural exanthem\/unilateral laterothoracic exanthem (APE\/ULE), papularpurpuric gloves and socks syndrome (PPGSS), and eruptive pseudo-angiomatosis (EP). Eruptive hypomelanosis (EH) is a newly discovered paraviral rash. Novel tools are now available to investigate the epidemiology of these rashes. To retrieve epidemiological data of these exanthema and analyze whether such substantiates or refutes infectious etiologies. We searched for articles published over the last 60 years and indexed by PubMed database. We then analyzed them for universality, demography, concurrent patients, temporal and spatial-temporal clustering, mini-epidemics, epidemics, and other clinical and geographical associations. Based on our criteria, we selected 55, 60, 29, 36, 20, and 4 articles for PR, GCS, APE\/ULE, PPGSS, EP, and EH respectively. Universality or multiple-continental reports are found for all exanthema except EH. The ages of patients are compatible with infectious causes for PR, GCS, APE\/ULE, and EH. Concurrent patients are reported for all. Significant patient clustering is demonstrated for PR and GCS. Mini-epidemics and epidemics have been reported for GCS, EP, and EH. The current epidemiological data supports, to a moderate extent, that PR, GCS, and APE could be caused by infectious agents. Support for PPGSS is marginal. Epidemiological evidences for infectious origins for EP and EH are inadequate. There might be growing epidemiological evidence to substantiate or to refute our findings in the future.<\/jats:p>","DOI":"10.4081\/idr.2016.6418","type":"journal-article","created":{"date-parts":[[2016,3,31]],"date-time":"2016-03-31T08:54:51Z","timestamp":1459414491000},"page":"6418","source":"Crossref","is-referenced-by-count":29,"title":["Pityriasis rosea, Gianotti-Crosti syndrome, asymmetric periflexural exanthem, papular-purpuric gloves and socks syndrome, eruptive pseudoangiomatosis, and eruptive hypomelanosis: do their epidemiological data substantiate infectious etiologies?"],"prefix":"10.3390","volume":"8","author":[{"given":"Antonio","family":"Chuh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay","family":"Zawar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel F.","family":"Sciallis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Werner","family":"Kempf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2016,3,21]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.jaad.2005.06.042","article-title":"Use of high-dose acyclovir in pityriasis rosea","volume":"54","author":"Drago","year":"2006","journal-title":"J Am Acad Dermatol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"181","DOI":"10.4103\/2229-5178.156389","article-title":"Acyclovir in pityriasis rosea: an observer-blind, randomized controlled trial of effectiveness, safety and tolerability","volume":"6","author":"Das","year":"2015","journal-title":"Indian 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A statistical, clinical and laboratory investigation of 826 patients and matched healthy controls","volume":"42","author":"Bj\u00f6rnberg","year":"1962","journal-title":"Acta Derm Venereol"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1159\/000363568","article-title":"Relapsing pityriasis rosea","volume":"229","author":"Drago","year":"2014","journal-title":"Dermatology"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1001\/archderm.1941.01500010069013","article-title":"Pityriasis rosea: report of three cases in one family with clinical variations in two of them","volume":"44","author":"Miller","year":"1941","journal-title":"Arch Dermatol Syph"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1159\/000319759","article-title":"Pityriasis rosea in a woman and her husband - case report and review of the literature","volume":"2","author":"Lemster","year":"2010","journal-title":"Case Rep 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