{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T22:34:07Z","timestamp":1722465247229},"reference-count":9,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2018,9,24]],"date-time":"2018-09-24T00:00:00Z","timestamp":1537747200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infectious Disease Reports"],"abstract":"<jats:p>Aspergillus is a common environmental mold most often recognized as an infectious agent in patients with severe immune compromise. We present a case of an immunocompetent patient presenting with endogenous endophthalmitis in the absence of other infectious symptoms. The search for a systemic source revealed an ascending aortic pseudoaneurysm. Surgical resection and pathology revealed angioinvasive aspergillus aortitis. Recent cardiac surgery has been noted to be a risk factor for angioinvasive aspergillosis. Diagnosis is difficult as symptoms are mild and laboratory studies are often normal. To our knowledge this is the first case of aspergillus aortitis presenting as endogenous endophthalmitis without systemic signs of inflammation. These patients have a high mortality rate therefore early recognition is essential. It is important to consider angioinvasive aspergillus infections in patients with prior cardiac surgery presenting with occult embolic phenomena. Only with early diagnosis and prompt treatment can we improve outcomes of this disease process.<\/jats:p>","DOI":"10.4081\/idr.2018.7750","type":"journal-article","created":{"date-parts":[[2018,10,9]],"date-time":"2018-10-09T09:36:43Z","timestamp":1539077803000},"page":"7750","source":"Crossref","is-referenced-by-count":5,"title":["Aspergillus Aortitis in an Immunocompetent Patient Presenting with Acute Endophthalmitis"],"prefix":"10.3390","volume":"10","author":[{"given":"Joseph M.","family":"Rocco","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maggie K.","family":"Benson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2018,9,24]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1111\/j.1469-0691.2006.01512.x","article-title":"Postoperative aspergillosis","volume":"12","author":"Pasqualotto","year":"2006","journal-title":"Clin Microbiol Infect"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/S0735-1097(02)02606-2","article-title":"Aspergillus Aortitis After Cardiac Surgery","volume":"41","author":"Sanchez-Recalde","year":"2003","journal-title":"JACC"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1111\/j.1540-8175.2006.00122.x","article-title":"Aspergillus niger Aortitis after Aortic Valve Replacement Diagnosed by Transesophageal Echocardiography","volume":"23","author":"Duygu","year":"2006","journal-title":"Echocardiography"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1016\/j.echo.2006.03.029","article-title":"Transesophageal echocardiographic diagnosis of Aspergillus fumigatus aortitis after percutaneous coronary intervention","volume":"19","author":"Khumri","year":"2006","journal-title":"J Am Soc Echocardiogr"},{"key":"ref5","first-page":"165","article-title":"Late occurrence of fatal aortitis: a complication of Aspergillus endocarditis following coronary artery bypass graft surgery","volume":"10","author":"Esmaeilzadeh","year":"2009","journal-title":"Eur J Echocardiogr"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1111\/j.1540-8175.2008.00776.x","article-title":"Fungal ascending aortic aneurysm after cardiac surgery","volume":"26","author":"Brili","year":"2009","journal-title":"Echocardiography"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.jvsc.2015.03.010","article-title":"Aspergillus thromboembolism from a mycotic ascending aortic pseudoaneurysm","volume":"1","author":"Skibba","year":"2015","journal-title":"J Vasc Surg Cases"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1016\/j.jvs.2011.04.056","article-title":"Acute aortic occlusion with sudden paraplegia secondary to Aspergillus niger embolism from Aspergillus niger aortitis","volume":"54","author":"Jamieson","year":"2011","journal-title":"J Vasc Surg"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1086\/503427","article-title":"Diagnosis of invasive aspergillosis using a galactomannan assay: a meta-analysis","volume":"42","author":"Pfeiffer","year":"2006","journal-title":"Clin Infect Dis"}],"container-title":["Infectious Disease Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.pagepress.org\/journals\/index.php\/idr\/article\/download\/7750\/7452","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.pagepress.org\/journals\/index.php\/idr\/article\/download\/7750\/7475","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.mdpi.com\/2036-7449\/10\/2\/7750\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,10]],"date-time":"2022-02-10T03:55:25Z","timestamp":1644465325000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2036-7449\/10\/2\/7750"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,24]]},"references-count":9,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2018,9]]}},"alternative-id":["idr.2018.7750"],"URL":"https:\/\/doi.org\/10.4081\/idr.2018.7750","relation":{},"ISSN":["2036-7449"],"issn-type":[{"value":"2036-7449","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9,24]]}}}