{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T05:31:25Z","timestamp":1775280685137,"version":"3.50.1"},"reference-count":23,"publisher":"PAGEPress Publications","issue":"2","license":[{"start":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T00:00:00Z","timestamp":1618272000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Monaldi Arch Chest Dis"],"abstract":"<jats:p>Patients with severe aortic stenosis are increasingly treated with transcatheter aortic valve implantation (TAVI) as a safer option to surgical aortic valve replacement (sAVR).\u00a0 Similar to many other heart diseases, after the specific therapeutic intervention patients are eligible for cardiac rehabilitation (CR) for the purpose of functional recovery. Thus far, CR after both sAVR and TAVI has been used to a limited extent, as shown by the availability of only two meta-analyses including 5 studies and 6 studies, respectively. Recent observational studies reported a significant improvement in functional indexes such as the Barthel scale and the 6-minute walk test (6MWT). We evaluated the outcome of CR in patients after TAVI treatment by measuring changes in the commonly used Barthel scale and 6MWT and adding the short physical performance battery (SPPB) scale as an index to assess lower extremity function. All indexes demonstrated a significant improvement, namely p&lt;0.001 with the Barthel scale, p=0.043 for the 6MWT, and p=0.002 for SPPB. These results confirm the significant improvement of the Barthel scale and 6MWT reported in the previous meta-analysis and suggest the utility of SPPB as a further index of efficacy of CR in patients with severe aortic stenosis treated with TAVI. \u00a0<\/jats:p>","DOI":"10.4081\/monaldi.2021.1621","type":"journal-article","created":{"date-parts":[[2021,4,14]],"date-time":"2021-04-14T04:25:09Z","timestamp":1618374309000},"source":"Crossref","is-referenced-by-count":11,"title":["Cardiac rehabilitation outcome after transcatheter aortic valve implantation"],"prefix":"10.4081","volume":"91","author":[{"given":"Chiara","family":"Penati","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3965-7988","authenticated-orcid":false,"given":"Cristoforo","family":"Incorvaia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina","family":"Mollo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federica","family":"Lietti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gemma","family":"Gatto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Stefanelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Centeleghe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Talarico","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ileana","family":"Mori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Franzelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fosco","family":"Ratti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Paola","family":"Ponticelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ermina","family":"Ridolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oreste Carlo","family":"Febo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2549","published-online":{"date-parts":[[2021,4,13]]},"reference":[{"key":"3540","unstructured":"Perera S, Wijesinghe N, Ly E, et al. Outcome of patients with untreated severe aortic stenosis in real-world practice. N Zeal Med J 2011;124:40-8."},{"key":"3541","doi-asserted-by":"crossref","unstructured":"Strange G, Stewart S, Celermajer D, et al. Poor long-term survival in patients with moderate aortic stenosis. J Am Coll Cardiol 2019;74:1851-63.","DOI":"10.1016\/j.jacc.2019.08.004"},{"key":"3542","doi-asserted-by":"crossref","unstructured":"Cribier AG. The odyssey of TAVR from concept to clinical reality. Tex Heart Inst J 2014;41:125-30.","DOI":"10.14503\/THIJ-14-4137"},{"key":"3543","doi-asserted-by":"crossref","unstructured":"Rostagno C. Heart valve disease in elderly. World J Cardiol 2019;11:71-83.","DOI":"10.4330\/wjc.v11.i2.71"},{"key":"3544","doi-asserted-by":"crossref","unstructured":"Randall MH, Bavry AA. Update on transcatheter aortic valve replacement. Cardiol Ther 2020;9:75-84.","DOI":"10.1007\/s40119-020-00167-6"},{"key":"3545","doi-asserted-by":"crossref","unstructured":"Liu Z, Kidney E, Bem D, et al. 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Exercise-based cardiac rehabilitation for patients following open surgical aortic valve replacement and transcatheter aortic valve implant: a systematic review and meta-analysis. Open Heart 2019;6:e000922."},{"key":"3552","unstructured":"Mahoney FI, Bartel DW. Functional evaluation: the Barthel index. Md State Med J 1965;14:61-5."},{"key":"3553","doi-asserted-by":"crossref","unstructured":"Guralnik, JM, Simonsick EM, Ferrucci L, et al. A short physical performance battery assessing lower extremity function: Association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol 1994;49:M85-94.","DOI":"10.1093\/geronj\/49.2.M85"},{"key":"3554","doi-asserted-by":"crossref","unstructured":"Enright PL, McBurnie MA, Bittner V, et al. The 6-min walk test: A quick measure of functional status in elderly adults. Chest 2003;123:387-98.","DOI":"10.1378\/chest.123.2.387"},{"key":"3555","unstructured":"Carnero-Alcazar, Maloto LM, Cobiella-Carnicer J, et al. Transcatheter versus surgical aortic valve replacement in moderate and high-risk patients: a meta-analysis. Eur Cardiothorac Surg 2017;51:644-52."},{"key":"3556","doi-asserted-by":"crossref","unstructured":"Panoulas VF, Francis DP, Ruparelia N, et al. Female-specific survival advantage from transcatheter aortic valve implantation over surgical aortic valve replacement: meta-analysis of the gender subgroups of randomized controlled trials including 3718 patients. Int J Cardio. 2018;250:66-72.","DOI":"10.1016\/j.ijcard.2017.05.047"},{"key":"3557","doi-asserted-by":"crossref","unstructured":"Eichler S, Salzwedel A, Reibis R, et al. Multicomponent cardiac rehabilitation in patients after transcatheter aortic valve implantation: Predictors of functional and psychocognitive recovery. Eur J Prev Cardiol 2017;24:257-64.","DOI":"10.1177\/2047487316679527"},{"key":"3558","doi-asserted-by":"crossref","unstructured":"Tarro Genta F, Tidu M, Bouslenko Z, et al. 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