{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T12:08:55Z","timestamp":1747224535156,"version":"3.40.5"},"reference-count":9,"publisher":"PAGEPress Publications","license":[{"start":{"date-parts":[[2021,6,10]],"date-time":"2021-06-10T00:00:00Z","timestamp":1623283200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Monaldi Arch Chest Dis"],"abstract":"<jats:p>Classic Hodgkin lymphomas are neoplasms originating from lymphoid tissue. Primary extranodal classic Hodgkin lymphoma (PE-cHL) of the lung is rare. A 37-year-old Caucasian male was referred to our hospital for recurrent episodes of hemoptysis, cough and bronchitis. A CT scan showed a massive left upper lung consolidation, which was positive at the PET scan. After several inconclusive tests and no benefit from medical therapies, the patient underwent a left upper lobectomy; pathology report showed a classical type Hodgkin lymphoma with no lymph-nodes involvement. Four cycles of adjuvant chemotherapy were administered with no toxicity. At the last follow up 14 months after surgery, the patient is alive and free from disease. Primary extranodal classical Hodgkin lymphoma of the lung is a rare entity, but it should be considered as a differential diagnosis in young patients with pulmonary consolidation even without systemic symptoms. \u00a0<\/jats:p>","DOI":"10.4081\/monaldi.2021.1781","type":"journal-article","created":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T06:31:39Z","timestamp":1623393099000},"source":"Crossref","is-referenced-by-count":1,"title":["Primary Hodgkin lymphoma of the lung arising with hemoptysis and pulmonary consolidation: a case report"],"prefix":"10.4081","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6267-0099","authenticated-orcid":false,"given":"Pietro","family":"Bertoglio","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Lomangino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6944-6508","authenticated-orcid":false,"given":"Giulia","family":"Querzoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Bonalumi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0311-2708","authenticated-orcid":false,"given":"Giuseppe S.","family":"Bogina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2272-0389","authenticated-orcid":false,"given":"Alberto C.","family":"Terzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2549","published-online":{"date-parts":[[2021,6,10]]},"reference":[{"key":"6017","doi-asserted-by":"crossref","unstructured":"Cooksley N, Judge DJ, Brown J. Primary pulmonary Hodkgin\u2019s Lymphoma and a review of the literature since 2006. BMJ Case Rep 2014;2014:bcr2014204020.","DOI":"10.1136\/bcr-2014-204020"},{"key":"6018","doi-asserted-by":"crossref","unstructured":"Rodriguez J, Tirabosco R, Pizzolitto S, et al. Hodgkin lymphoma presenting with exclusive or preponderant pulmonary involvement: a clinicopathologic study of 5 new cases. Ann Diagn Pathol 2006;10:83-8.","DOI":"10.1016\/j.anndiagpath.2005.07.014"},{"key":"6019","doi-asserted-by":"crossref","unstructured":"Cheson BD, Fisher RI, Barrington SF, et al. Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the Lugano classification. J Clin Oncol 2014;32:3059-68.","DOI":"10.1200\/JCO.2013.54.8800"},{"key":"6020","doi-asserted-by":"crossref","unstructured":"Cavalli F, Stein H, Zucca E. Extranodal lymphomas pathology and management. Informa: London; 2008","DOI":"10.3109\/9780203091753"},{"key":"6021","doi-asserted-by":"crossref","unstructured":"Yang M, Ping L, Liu W, et al. Clinical characteristics and prognostic factors of primary extranodal classical Hodgkin lymphoma: a retrospective study. Hematology 2019;24:413-9.","DOI":"10.1080\/16078454.2019.1598678"},{"key":"6022","doi-asserted-by":"crossref","unstructured":"Kumar R, Sidhu H, Mistry R, Shet T, Primary pulmonary Hodgkin's lymphoma: a rare pitfall in transthoracic fine needle aspiration cytology. Diagn Cytopathol 2008;36:666-9.","DOI":"10.1002\/dc.20872"},{"key":"6023","doi-asserted-by":"crossref","unstructured":"O'Malley DP, Dogan A, Fedoriw Y, et al. American Registry of Pathology Expert Opinions: Immunohistochemical evaluation of classic Hodgkin lymphoma. Ann Diagn Pathol 2019;39:105-10.","DOI":"10.1016\/j.anndiagpath.2019.02.001"},{"key":"6024","doi-asserted-by":"crossref","unstructured":"Muzzafar T, Wei EX, Lin P, et al. Flow cytometric immunophenotyping of anaplastic large cell lymphoma. Arch Pathol Lab Med 2009;133:49-56.","DOI":"10.5858\/133.1.49"},{"key":"6025","doi-asserted-by":"crossref","unstructured":"Gulley ML, Glaser SL, Craig FE, et al., Guidelines for interpreting EBER in situ hybridization and LMP1 immunohistochemical tests for detecting Epstein-Barr virus in Hodgkin lymphoma. Am J Clin Pathol 2002;117:259-67.","DOI":"10.1309\/MMAU-0QYH-7BHA-W8C2"}],"container-title":["Monaldi Archives for Chest Disease"],"original-title":[],"link":[{"URL":"https:\/\/monaldi-archives.org\/index.php\/macd\/article\/download\/1781\/1275","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/monaldi-archives.org\/index.php\/macd\/article\/download\/1781\/1275","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T06:32:29Z","timestamp":1623393149000},"score":1,"resource":{"primary":{"URL":"https:\/\/monaldi-archives.org\/index.php\/macd\/article\/view\/1781"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,10]]},"references-count":9,"URL":"https:\/\/doi.org\/10.4081\/monaldi.2021.1781","relation":{},"ISSN":["2532-5264","1122-0643"],"issn-type":[{"type":"electronic","value":"2532-5264"},{"type":"print","value":"1122-0643"}],"subject":[],"published":{"date-parts":[[2021,6,10]]}}}