{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T12:09:00Z","timestamp":1747224540029,"version":"3.40.5"},"reference-count":12,"publisher":"PAGEPress Publications","license":[{"start":{"date-parts":[[2021,11,16]],"date-time":"2021-11-16T00:00:00Z","timestamp":1637020800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Monaldi Arch Chest Dis"],"abstract":"<jats:p>Desmoplastic small round cell tumor (DSRCT) is a rare, extremely aggressive and malignant tumor predominantly affects young adolescent males and typically presents as a large intra-abdominal mass. However, tumor arising from other body sites are also reported in the literature. Histology and immunohistochemistry play an important role in the diagnosis and differentiating this rare tumor from other round cell tumors. A multidisciplinary approach consisting of a combination of surgery, chemotherapy and radiation therapy is the treatment of choice as there is no standard therapy.\u00a0 We report a case of DSRCT of pleura presenting as bilateral pleural effusion in a young adolescent male who was treated with both surgery and chemotherapy. However patient succumbed to death after one year of diagnosis.<\/jats:p>","DOI":"10.4081\/monaldi.2021.1874","type":"journal-article","created":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T07:39:37Z","timestamp":1637134777000},"source":"Crossref","is-referenced-by-count":2,"title":["A rare cause of bilateral pleural effusion \u2013 desmoplastic small round cell tumor"],"prefix":"10.4081","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4661-3414","authenticated-orcid":false,"given":"Archana","family":"Baburao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2746-7420","authenticated-orcid":false,"given":"Poonam","family":"Maurya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amulya","family":"Chakenahalli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huliraj","family":"Narayanswamy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2549","published-online":{"date-parts":[[2021,11,16]]},"reference":[{"key":"11903","doi-asserted-by":"crossref","unstructured":"Gerald WL, Rosai J. Case2. Desmoplastic small round cell tumor with divergent differentiation. Paediatr Pathol 1989;9:177\u201383.","DOI":"10.3109\/15513818909022347"},{"key":"11904","doi-asserted-by":"crossref","unstructured":"Ordonez N, Zirkin R, Bloom RE. Malignant small-cell epithelial tumor of the peritoneum expressing mesenchymal-type inter-mediate filaments. Am J Surg Pathol 1989;13:413\u201321.","DOI":"10.1097\/00000478-198905000-00009"},{"key":"11905","doi-asserted-by":"crossref","unstructured":"Thuret R, Renaudin K, Leclere J, et al. Uncommon malignancies: Paratesticular desmoplastic small round-cell tumor. J Clin Oncol. 2005;23:6253\u20135.","DOI":"10.1200\/JCO.2005.07.006"},{"key":"11906","doi-asserted-by":"crossref","unstructured":"Parkash V, Gerald W.L, Parma A, et al. Desmoplastic small round cell tumor of the pleura. Am J Surg Pathol 1995;19:659\u201365.","DOI":"10.1097\/00000478-199506000-00006"},{"key":"11907","doi-asserted-by":"crossref","unstructured":"Bellah R, Suzuki-Bordalo L, Brecher E J, et al. Desmoplastic small round cell tumor in the abdomen and pelvis: report of CT findings in 11 affected children and young adults. AJR Am J Roentgenol 2005;184:1910-4.","DOI":"10.2214\/ajr.184.6.01841910"},{"key":"11908","doi-asserted-by":"crossref","unstructured":"Biswas G, Laskar S, Banavali SD, et al. Desmoplastic small round cell tumor: extra abdominal and abdominal presentations and the results of treatment. Indian J Cancer 2005;42:78-84.","DOI":"10.4103\/0019-509X.16696"},{"key":"11909","doi-asserted-by":"crossref","unstructured":"Fois A.G, Pirina P, Arcadu A, et al. Desmoplastic small round cell tumors of the pleura: a review of the clinical literature. Multidiscip Respir Med 2017;12:22.","DOI":"10.4081\/mrm.2017.248"},{"key":"11910","doi-asserted-by":"crossref","unstructured":"Scheer M, Vokuhl C, Blank B, et al. Desmoplastic small round cell tumors: Multimodality treatment and new risk factors. Cancer Med 2019;8:527\u201342.","DOI":"10.1002\/cam4.1940"},{"key":"11911","doi-asserted-by":"crossref","unstructured":"Lae ME, Roche PC, Jin L,et al. Desmoplastic small round cell tumor: A clinicopathologic, immunohistochemical, and molecular study of 32 tumors. Am J Surg Pathol 2002;26:823-35.","DOI":"10.1097\/00000478-200207000-00001"},{"key":"11912","doi-asserted-by":"crossref","unstructured":"Goodman KA, Wolden SL, La Quaglia MP, Kushner BH. Whole abdomino-pelvic radiotherapy for desmoplastic small round cell tumor. Int J Radiat Oncol Biol Phys 2002;1:170-6.","DOI":"10.1016\/S0360-3016(02)02871-7"},{"key":"11913","doi-asserted-by":"crossref","unstructured":"Watanabe T, Miyamoto S, Kitagori K, et al. A case of long\u2011term survival of metastatic desmoplastic small round cell tumor treated with multimodal therapy. Oncol Lett 2012;3:30\u20114.","DOI":"10.3892\/ol.2011.457"},{"key":"11914","doi-asserted-by":"crossref","unstructured":"Lal DR, Su WT, Wolden SL, et al. Results of multimodal treatment for desmoplastic small round cell tumors. J Pediatr Surg 2005;40:251\u20135.","DOI":"10.1016\/j.jpedsurg.2004.09.046"}],"container-title":["Monaldi Archives for Chest Disease"],"original-title":[],"link":[{"URL":"https:\/\/www.monaldi-archives.org\/index.php\/macd\/article\/download\/1874\/1363","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.monaldi-archives.org\/index.php\/macd\/article\/download\/1874\/1363","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T07:39:56Z","timestamp":1637134796000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.monaldi-archives.org\/index.php\/macd\/article\/view\/1874"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,16]]},"references-count":12,"URL":"https:\/\/doi.org\/10.4081\/monaldi.2021.1874","relation":{},"ISSN":["2532-5264","1122-0643"],"issn-type":[{"type":"electronic","value":"2532-5264"},{"type":"print","value":"1122-0643"}],"subject":[],"published":{"date-parts":[[2021,11,16]]}}}