{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T12:27:56Z","timestamp":1748003276110,"version":"3.40.5"},"reference-count":17,"publisher":"PAGEPress Publications","license":[{"start":{"date-parts":[[2021,9,28]],"date-time":"2021-09-28T00:00:00Z","timestamp":1632787200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Monaldi Arch Chest Dis"],"abstract":"<jats:p>A 52-year-old man was re-admitted two weeks after recovering from severe COVD-19 following a 3-days history of cough and worsening shortness of breath. The chest radiograph showed a large right-sided pneumothorax. The first attempt at drainage, performed through a large bored tube, failed. Due to the large dimension of the pneumothorax, and the lung condition (extensive consolidation and diffuse bullous dystrophies), the only thoracic surgical approach prospected was a pneumonectomy. Willing to preserve the lung, the pulmonology team attempted a multi-phase medical-oriented strategy based on medical thoracoscopy. Therefore, the patient underwent 5 chest tube insertions, 2 talc pleurodesis, and an intrapleural blood patch. Air leakage resolution was progressively achieved, and the patient became asymptomatic.\n\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 We strongly encourage a medical thoracoscopic approach for the patient presenting with recurrent pneumothorax in order to ensure complete lung re-expansion and preserve lung parenchyma.<\/jats:p>","DOI":"10.4081\/monaldi.2021.1956","type":"journal-article","created":{"date-parts":[[2021,9,29]],"date-time":"2021-09-29T07:00:35Z","timestamp":1632898835000},"source":"Crossref","is-referenced-by-count":4,"title":["Full medical treatment of COVID-19 associated large pneumothorax - A case report"],"prefix":"10.4081","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5707-775X","authenticated-orcid":false,"given":"Alberto","family":"Fantin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadia","family":"Castaldo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Vailati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Morana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6984-3936","authenticated-orcid":false,"given":"Vincenzo","family":"Patruno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2549","published-online":{"date-parts":[[2021,9,28]]},"reference":[{"key":"10312","doi-asserted-by":"crossref","unstructured":"Yasukawa K, Vamadevan A, Rollins R. Bulla formation and tension pneumothorax in a patient with COVID-19. Am J Trop Med Hyg 2020;103:943-4.","DOI":"10.4269\/ajtmh.20-0736"},{"key":"10313","doi-asserted-by":"crossref","unstructured":"Al-Shokri SD, Ahmed AOE, Saleh AO, et al. Case Report: COVID-19-related pneumothorax-case series highlighting a significant complication. Am J Trop Med Hyg 2020;103:1166-9.","DOI":"10.4269\/ajtmh.20-0713"},{"key":"10314","doi-asserted-by":"crossref","unstructured":"McGuinness G, Zhan C, Rosenberg N, et al. Increased incidence of barotrauma in patients with COVID-19 on invasive mechanical ventilation. Radiology 2020;297:E252-62.","DOI":"10.1148\/radiol.2020202352"},{"key":"10315","doi-asserted-by":"crossref","unstructured":"Flower L, Carter J-PL, Lopez JR Henry AM. Tension pneumothorax in a patient with COVID-19. BMJ Case Rep 2020;13:e235861.","DOI":"10.1136\/bcr-2020-235861"},{"key":"10316","doi-asserted-by":"crossref","unstructured":"Nunna K, Braun AB. Development of a large spontaneous pneumothorax after recovery from mild COVID-19 infection. BMJ Case Rep 2021;14:e238863.","DOI":"10.1136\/bcr-2020-238863"},{"key":"10317","doi-asserted-by":"crossref","unstructured":"Akdogan RE, Mohammed T, Syeda A, et al. Pneumothorax in mechanically ventilated patients with COVID-19 infection. Case Rep Crit Care 2021;2021:6657533.","DOI":"10.1155\/2021\/6657533"},{"key":"10318","doi-asserted-by":"crossref","unstructured":"Quincho-Lopez A, Quincho-Lopez DL, Hurtado-Medina FD. Case Report: Pneumothorax and pneumomediastinum as uncommon complications of COVID-19 pneumonia-Literature review. Am J Trop Med Hyg 2020;103:1170-6.","DOI":"10.4269\/ajtmh.20-0815"},{"key":"10319","doi-asserted-by":"crossref","unstructured":"Hazariwala V, Hadid H, Kirsch D, Big C. Spontaneous pneumomediastinum, pneumopericardium, pneumothorax and subcutaneous emphysema in patients with COVID-19 pneumonia, a case report. J Cardiothorac Surg 2020;15:301.","DOI":"10.1186\/s13019-020-01308-7"},{"key":"10320","doi-asserted-by":"crossref","unstructured":"Mir\u00f3 O, Lorens P, Jim\u00e9nez S, et al. Frequency, risk factors, clinical characteristics, and outcomes of spontaneous pneumothorax in patients with coronavirus disease 2019: A case-control, emergency medicine-based multicenter study. Chest 2021;159:1241-55.","DOI":"10.1016\/j.chest.2020.11.013"},{"key":"10321","doi-asserted-by":"crossref","unstructured":"do Lago VC, Jacon Cezare T, Castelo Branco Fortaleza CM, et al. Does COVID-19 increase the risk for spontaneous pneumothorax? Am J Med Sci 2020;360:735-7.","DOI":"10.1016\/j.amjms.2020.07.024"},{"key":"10322","doi-asserted-by":"crossref","unstructured":"Liu K, Zeng Y, Xie P, et al. COVID-19 with cystic features on computed tomography: A case report. Medicine (Baltimore) 2020;99:e20175.","DOI":"10.1097\/MD.0000000000020175"},{"key":"10323","doi-asserted-by":"crossref","unstructured":"Ucpinar BA, Sahin C, Yanc U. Spontaneous pneumothorax and subcutaneous emphysema in COVID-19 patient: Case report. J Infect Public Health 2020;13:887-9.","DOI":"10.1016\/j.jiph.2020.05.012"},{"key":"10324","doi-asserted-by":"crossref","unstructured":"Guan WJ, Ni ZY, Hu Y, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med 2020;382:1708-20.","DOI":"10.1056\/NEJMoa2002032"},{"key":"10325","doi-asserted-by":"crossref","unstructured":"Slade M. Management of pneumothorax and prolonged air leak. Semin Respir Crit Care Med 2014;35:706-14.","DOI":"10.1055\/s-0034-1395502"},{"key":"10326","unstructured":"Parrish S, Browning RF, Turner JF, Jr, et al. The role for medical thoracoscopy in pneumothorax. J Thorac Dis 2014;6:S383-91."},{"key":"10327","doi-asserted-by":"crossref","unstructured":"Aiolfi A, Biraghi T, Montisci A, et al. Management of persistent pneumothorax with thoracoscopy and bleb resection in COVID-19 patients. Ann Thorac Surg 2020;110:e413-5.","DOI":"10.1016\/j.athoracsur.2020.04.011"},{"key":"10328","unstructured":"Jeon HW, Kim YD, Choi SY, Park JK. When is the optimal timing of the surgical treatment for secondary spontaneous pneumothorax? Thorac Cardiovasc Surg 2017;65:50-5."}],"container-title":["Monaldi Archives for Chest Disease"],"original-title":[],"link":[{"URL":"https:\/\/monaldi-archives.org\/index.php\/macd\/article\/download\/1956\/1344","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/monaldi-archives.org\/index.php\/macd\/article\/download\/1956\/1344","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,29]],"date-time":"2021-09-29T07:02:03Z","timestamp":1632898923000},"score":1,"resource":{"primary":{"URL":"https:\/\/monaldi-archives.org\/index.php\/macd\/article\/view\/1956"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,28]]},"references-count":17,"URL":"https:\/\/doi.org\/10.4081\/monaldi.2021.1956","relation":{},"ISSN":["2532-5264","1122-0643"],"issn-type":[{"type":"electronic","value":"2532-5264"},{"type":"print","value":"1122-0643"}],"subject":[],"published":{"date-parts":[[2021,9,28]]}}}