{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T12:09:15Z","timestamp":1747224555084,"version":"3.40.5"},"reference-count":14,"publisher":"PAGEPress Publications","license":[{"start":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T00:00:00Z","timestamp":1667347200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Monaldi Arch Chest Dis"],"abstract":"<jats:p>Coronavirus disease 2019 (COVID-19) continues to be a disease of global importance, with an increasing array of sequelae attributed to infection by the severe acute respiratory syndrome coronavirus-2. One such complication that has been rarely documented thus far is diaphragmatic dysfunction. Here, we report the cases of 2 individuals who developed diaphragmatic paralysis post COVID-19, which failed to respond to conservative management. Both patients proceeded to undergo robot-assisted thoracoscopic plication of the diaphragm reinforced with a bovine acellular dermal matrix. In both cases, there was significant improvement in symptomatology, namely dyspnoea and fatigue. We conclude that robot-assisted diaphragmatic plication should be considered for the treatment of refractory diaphragmatic paralysis post COVID-19.<\/jats:p>","DOI":"10.4081\/monaldi.2022.2367","type":"journal-article","created":{"date-parts":[[2022,11,4]],"date-time":"2022-11-04T10:30:32Z","timestamp":1667557832000},"source":"Crossref","is-referenced-by-count":0,"title":["Diaphragmatic paralysis post COVID-19 treated with robot-assisted plication reinforced with acellular dermal matrix: a report of two cases"],"prefix":"10.4081","author":[{"given":"Patrick","family":"Hurley","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1038-2546","authenticated-orcid":false,"given":"Adam","family":"Djouani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2827-5826","authenticated-orcid":false,"given":"Savvas","family":"Lampridis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Bill\u00e8","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2549","published-online":{"date-parts":[[2022,11,2]]},"reference":[{"key":"22341","doi-asserted-by":"crossref","unstructured":"Shi Z, de Vries HJ, Vlaar APJ, et al. Diaphragm pathology in critically ill patients with COVID-19 and postmortem findings from 3 medical centers. JAMA Intern Med 2021;181:122\u20134.","DOI":"10.1001\/jamainternmed.2020.6278"},{"key":"22342","doi-asserted-by":"crossref","unstructured":"Farr E, Wolfe AR, Deshmukh S, et al. Diaphragm dysfunction in severe COVID-19 as determined by neuromuscular ultrasound. Ann Clin Transl Neurol 2021;8:1745\u20139.","DOI":"10.1002\/acn3.51416"},{"key":"22343","doi-asserted-by":"crossref","unstructured":"FitzMaurice TS, McCann C, Walshaw M, Greenwood J. Unilateral diaphragm paralysis with COVID-19 infection. BMJ Case Rep 2021;14:e243115.","DOI":"10.1136\/bcr-2021-243115"},{"key":"22344","doi-asserted-by":"crossref","unstructured":"Paliwal VK, Garg RK, Gupta A, Tejan N. Neuromuscular presentations in patients with COVID-19. Neurol Sci 2020;41:3039\u201356.","DOI":"10.1007\/s10072-020-04708-8"},{"key":"22345","doi-asserted-by":"crossref","unstructured":"Wu Y, Xu X, Chen Z, et al. Nervous system involvement after infection with COVID-19 and other coronaviruses. Brain Behav Immun 2020;87:18\u201322.","DOI":"10.1016\/j.bbi.2020.03.031"},{"key":"22346","doi-asserted-by":"crossref","unstructured":"Saif A, Pick A. Polyneuropathy following COVID-19 infection: the rehabilitation approach. BMJ Case Rep 2021;14:e242330.","DOI":"10.1136\/bcr-2021-242330"},{"key":"22347","doi-asserted-by":"crossref","unstructured":"Ramani SL, Samet J, Franz CK, et al. Musculoskeletal involvement of COVID-19: review of imaging. Skeletal Radiol 2021;50:1763\u201373.","DOI":"10.1007\/s00256-021-03734-7"},{"key":"22348","doi-asserted-by":"crossref","unstructured":"Dong Z, Liu Y, Gai Y, et al. Early rehabilitation relieves diaphragm dysfunction induced by prolonged mechanical ventilation: a randomised control study. BMC Pulm Med 2021;21:106.","DOI":"10.1186\/s12890-021-01461-2"},{"key":"22349","unstructured":"O\u2019Toole SM, Kramer J. Unilateral diaphragmatic paralysis. Treasure Island: StatPearls Publishing; 2022."},{"key":"22350","doi-asserted-by":"crossref","unstructured":"Wright CD, Williams JG, Ogilvie CM, Donnelly RJ. Results of diaphragmatic plication for unilateral diaphragmatic paralysis. J Thorac Cardiovasc Surg 1985;90:195\u20138.","DOI":"10.1016\/S0022-5223(19)38619-2"},{"key":"22351","doi-asserted-by":"crossref","unstructured":"Freeman RK, Wozniak TC, Fitzgerald EB. Functional and physiologic results of video-assisted thoracoscopic diaphragm plication in adult patients with unilateral diaphragm paralysis. Ann Thorac Surg 2006;81:1853\u20137.","DOI":"10.1016\/j.athoracsur.2005.11.068"},{"key":"22352","doi-asserted-by":"crossref","unstructured":"Celik S, Celik M, Aydemir B, et al. Long-term results of diaphragmatic plication in adults with unilateral diaphragm paralysis. J Cardiothorac Surg 2010;5:111.","DOI":"10.1186\/1749-8090-5-111"},{"key":"22353","doi-asserted-by":"crossref","unstructured":"Nardini M, Jayakumar S, Migliore M, et al. Minimally invasive plication of the diaphragm: A single-center prospective study. Innovations (Phila) 2021;16:343\u20139.","DOI":"10.1177\/15569845211011583"},{"key":"22354","doi-asserted-by":"crossref","unstructured":"Lampridis S, Pradeep IS, Bill\u00e8 A. Robotic\u2010assisted diaphragmatic plication: Improving safety and effectiveness in the treatment of diaphragmatic paralysis. 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