{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T01:27:48Z","timestamp":1771637268892,"version":"3.50.1"},"reference-count":10,"publisher":"PAGEPress Publications","license":[{"start":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T00:00:00Z","timestamp":1674777600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Monaldi Arch Chest Dis"],"abstract":"<jats:p>Mucormycosis is a fatal angio-invasive fungal infection associated with a high mortality. Apart from the traditional risk factors, COVID-19 infection and steroid therapy for the same have been recently identified to predispose to this life-threatening infection. Usual presentations of mucormycosis include rhino-orbito-cerebral, pulmonary, gastrointestinal, renal and cutaneous involvement. We report an unusual case of mediastinal involvement by mucormycosis in a patient recovering from moderate COVID-19 pneumonia. Early diagnosis, prompt initiation of antifungal therapy accompanied by timely surgical debridement were pivotal in averting morbidity and mortality in this patient.<\/jats:p>","DOI":"10.4081\/monaldi.2023.2472","type":"journal-article","created":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T09:55:32Z","timestamp":1674813332000},"source":"Crossref","is-referenced-by-count":2,"title":["A case of hoarseness of voice following COVID-19 infection"],"prefix":"10.4081","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2869-4054","authenticated-orcid":false,"given":"Ruby","family":"Joseph","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kavitha","family":"Venkatnarayan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3112-399X","authenticated-orcid":false,"given":"Ashitha","family":"Nanaiah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priya","family":"Ramachandran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2549","published-online":{"date-parts":[[2023,1,27]]},"reference":[{"key":"24349","doi-asserted-by":"crossref","unstructured":"Prakash H, Ghosh AK, Rudramurthy SM, et al. A prospective multicenter study on mucormycosis in India: Epidemiology, diagnosis, and treatment. Med Mycol 2019;57:395-402.","DOI":"10.1093\/mmy\/myy060"},{"key":"24350","doi-asserted-by":"crossref","unstructured":"Landstra CP, de Koning EJP. COVID-19 and diabetes: Understanding the interrelationship and risks for a severe course. Front Endocrinol 2021;12:649525.","DOI":"10.3389\/fendo.2021.649525"},{"key":"24351","doi-asserted-by":"crossref","unstructured":"Muthu V, Rudramurthy SM, Chakrabarti A, et al. Epidemiology and pathophysiology of COVID-19-associated mucormycosis: India versus the rest of the world. Mycopathologia 2021;186:739\u201354.","DOI":"10.1007\/s11046-021-00584-8"},{"key":"24352","doi-asserted-by":"crossref","unstructured":"Hoenigl M, Seidel D, Carvalho A, et al. The emergence of COVID-19 associated mucormycosis: a review of cases from 18 countries. Lancet Microbe 2022;3:e543\u201352.","DOI":"10.1016\/S2666-5247(21)00237-8"},{"key":"24353","doi-asserted-by":"crossref","unstructured":"Rudramurthy SM, Hoenigl M, Meis JF, et al. ECMM\/ISHAM recommendations for clinical management of COVID\u201019 associated mucormycosis in low\u2010 and middle\u2010income countries. Mycoses 2021;64:1028\u201337.","DOI":"10.1111\/myc.13335"},{"key":"24354","doi-asserted-by":"crossref","unstructured":"Dhooria S, Agarwal R, Chakrabarti A. Mediastinitis and bronchial perforations due to mucormycosis. J Bronchol Interv Pulmonol 2015;22:338\u201342.","DOI":"10.1097\/LBR.0000000000000170"},{"key":"24355","doi-asserted-by":"crossref","unstructured":"Connor BA, Anderson RJ, Smith JW. Mucor mediastinitis. Chest 1979;75:524\u20136.","DOI":"10.1378\/chest.75.4.524"},{"key":"24356","doi-asserted-by":"crossref","unstructured":"Liu HC, Jan MS, Lin YC, et al. A rare pulmonary zygomycosis manifested as chronic mediastinitis and bronchial perforation. Eur Respir J 2011;38:734\u20135.","DOI":"10.1183\/09031936.00155110"},{"key":"24357","doi-asserted-by":"crossref","unstructured":"Muthu V, Agarwal R, Patel A, et al. Definition, diagnosis, and management of COVID-19-associated pulmonary mucormycosis: Delphi consensus statement from the Fungal Infection Study Forum and Academy of Pulmonary Sciences, India. Lancet Infect Dis 2022;22:e240-53.","DOI":"10.1016\/S1473-3099(22)00124-4"},{"key":"24358","doi-asserted-by":"crossref","unstructured":"Cooper JD, Gotoff RA, Foltzer MA, et al. Mediastinal mucormycosis: Case report, review of literature and treatment with continuous liposomal amphotericin B irrigation. Mycoses 2019;62:739-45.","DOI":"10.1111\/myc.12922"}],"container-title":["Monaldi Archives for Chest Disease"],"original-title":[],"link":[{"URL":"https:\/\/www.monaldi-archives.org\/index.php\/macd\/article\/download\/2472\/1603","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.monaldi-archives.org\/index.php\/macd\/article\/download\/2472\/1603","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T09:55:40Z","timestamp":1674813340000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.monaldi-archives.org\/index.php\/macd\/article\/view\/2472"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,27]]},"references-count":10,"URL":"https:\/\/doi.org\/10.4081\/monaldi.2023.2472","relation":{},"ISSN":["2532-5264","1122-0643"],"issn-type":[{"value":"2532-5264","type":"electronic"},{"value":"1122-0643","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1,27]]}}}