{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T12:09:23Z","timestamp":1747224563788,"version":"3.40.5"},"reference-count":12,"publisher":"PAGEPress Publications","license":[{"start":{"date-parts":[[2023,2,16]],"date-time":"2023-02-16T00:00:00Z","timestamp":1676505600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Monaldi Arch Chest Dis"],"abstract":"<jats:p>Thiamine deficiency is commonly associated with malnutrition, alcoholism and bariatric surgery. Thiamine deficiency can manifest in different ways, especially in developing countries: as peripheric neuropathy, as Wernicke encephalopathy or as beriberi disease. The authors present the case of a 72-year-old male, with a hiatal hernia that led to thiamine deficiency due to malnutrition. The initial clinical manifestation was an ST-elevation myocardial infarct equivalent, an ECG with a shark-fin pattern that evolved to a Wellens type B pattern. The patient evolved with severe altered mental status. A Wernicke encephalopathy diagnosis was confirmed by MRI; the patient was medicated with high-dose thiamine, with quick recovery, both neurologic and cardiac. The clinical history and response to treatment confirm the diagnosis of Wernicke encephalopathy and beriberi disease.<\/jats:p>","DOI":"10.4081\/monaldi.2023.2513","type":"journal-article","created":{"date-parts":[[2023,3,3]],"date-time":"2023-03-03T12:54:32Z","timestamp":1677848072000},"source":"Crossref","is-referenced-by-count":2,"title":["Wernicke encephalopathy and beriberi disease presenting as STEMI-equivalent"],"prefix":"10.4081","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0671-009X","authenticated-orcid":false,"given":"Miguel","family":"Martins Carvalho","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T\u00e2nia","family":"Proen\u00e7a","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1002-9985","authenticated-orcid":false,"given":"Ricardo","family":"Alves Pinto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0472-4076","authenticated-orcid":false,"given":"Roberto","family":"Pinto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filipe","family":"Macedo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2549","published-online":{"date-parts":[[2023,2,16]]},"reference":[{"key":"24898","unstructured":"Wiley KD, Gupta M. Vitamin B1 thiamine deficiency. In: StatPearls [Internet]. Treasure Island: StatPearls Publishing; 2022."},{"key":"24899","unstructured":"Yamashita N, Aikawa T. Dutch research on beriberi: I. Christiaan Eijkman's research and evaluation of Kanehiro Takaki's diet reforms of the Japanese navy. Nihon Ishigaku Zasshi 2017;63:3-21."},{"key":"24900","doi-asserted-by":"crossref","unstructured":"Kuzume D, Inoue Y, Morimoto Y, et al. [Diuretics-induced beriberi polyneuropathy: a case report].[Article in Japanese]. Rinsho Shinkeigaku 2022;62:641-3.","DOI":"10.5692\/clinicalneurol.cn-001762"},{"key":"24901","doi-asserted-by":"crossref","unstructured":"Daly MJ, Dixon LJ, A case of ST-elevation and nystagmus--when coronary thrombosis is not to blame. QJM 2009;102:737-9.","DOI":"10.1093\/qjmed\/hcp095"},{"key":"24902","doi-asserted-by":"crossref","unstructured":"Kawano H, Koide Y, Toda G, Yanok. ST-segment elevation of electrocardiogram in a patient with Shoshin beriberi. Intern Med 2005;44:578-85.","DOI":"10.2169\/internalmedicine.44.578"},{"key":"24903","doi-asserted-by":"crossref","unstructured":"Coelho LS, Hueb JC, Minicucci MF, et al, Thiamin deficiency as a cause of reversible cor pulmonale. Arq Bras Cardiol 2008;91:e7-9.","DOI":"10.1590\/S0066-782X2008001300013"},{"key":"24904","unstructured":"Wenckebach KF. [Das Beriberi-Herz: Morphologie, Klinik, Pathogenese].[Book in German]. Julius Springer: Berlin; 1934."},{"key":"24905","doi-asserted-by":"crossref","unstructured":"Akbarian M, Yankopoulos NA, Abelmann WH. Hemodynamic studies in beriberi heart disease. Am J Med 1966;41:197-212.","DOI":"10.1016\/0002-9343(66)90016-7"},{"key":"24906","doi-asserted-by":"crossref","unstructured":"Blankenhorn MA, Vilter CF, Scheinker IM, et al. Occidental beriberi heart disease. J Am Med Assoc 1946;131:717-26.","DOI":"10.1001\/jama.1946.02870260001001"},{"key":"24907","doi-asserted-by":"crossref","unstructured":"Helali J, Park S, Ziaeian B, et al. Thiamine and heart failure: Challenging cases of modern-day cardiac beriberi. Mayo Clin Proc Innov Qual Outcomes 2019;3:221-5.","DOI":"10.1016\/j.mayocpiqo.2019.03.003"},{"key":"24908","doi-asserted-by":"crossref","unstructured":"Hanninen SA, Darling PB, Sole MJ, et al. The prevalence of thiamin deficiency in hospitalized patients with congestive heart failure. J Am Coll Cardiol 2006;47:354-61.","DOI":"10.1016\/j.jacc.2005.08.060"},{"key":"24909","doi-asserted-by":"crossref","unstructured":"Jain A, Mehta R, Al-Ani M, et al. Determining the role of thiamine deficiency in systolic heart failure: A meta-analysis and systematic review. J Card Fail 2015;21:1000-7.","DOI":"10.1016\/j.cardfail.2015.10.005"}],"container-title":["Monaldi Archives for Chest Disease"],"original-title":[],"link":[{"URL":"https:\/\/www.monaldi-archives.org\/index.php\/macd\/article\/download\/2513\/1621","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.monaldi-archives.org\/index.php\/macd\/article\/download\/2513\/1621","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,3]],"date-time":"2023-03-03T12:54:44Z","timestamp":1677848084000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.monaldi-archives.org\/index.php\/macd\/article\/view\/2513"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,16]]},"references-count":12,"URL":"https:\/\/doi.org\/10.4081\/monaldi.2023.2513","relation":{},"ISSN":["2532-5264","1122-0643"],"issn-type":[{"type":"electronic","value":"2532-5264"},{"type":"print","value":"1122-0643"}],"subject":[],"published":{"date-parts":[[2023,2,16]]}}}