{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T22:41:59Z","timestamp":1770244919130,"version":"3.49.0"},"reference-count":17,"publisher":"PAGEPress Publications","issue":"4","license":[{"start":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T00:00:00Z","timestamp":1731024000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Monaldi Arch Chest Dis"],"abstract":"<jats:p>COVID-19 affected millions of people worldwide, and tuberculosis (TB) continues to affect millions of people each year. The combined pandemic of COVID-19 and TB had a catastrophic effect on healthcare policies and healthcare setups around the globe. The clinical profile and factors affecting the outcome of COVID-19 disease in TB patients on treatment in field conditions have not been studied in detail. The present study attempted to study the occurrence of COVID-19 among patients on TB treatment in terms of the severity of COVID-19 disease and outcome of both COVID-19 and TB in patients at National Tuberculosis Elimination Program treatment centers over a period of one year during peak COVID-19 times. Out of 1400 TB patients enrolled, 65 (5%) suffered from COVID-19 disease. Of the 65 TB patients with COVID-19 disease, 37 (57%) were male and under 45 years old, 33 (51%) had a TB diagnosis after first receiving a COVID-19 diagnosis, 29 (45%) had a TB diagnosis first and received anti-TB treatment before receiving a COVID-19 diagnosis, and only 3 patients (5%) had a COVID-19 and TB diagnosis concurrently. The majority of 59 (91%) patients had mild COVID-19 disease. The outcome of TB treatment was available in 25 patients out of these 65 COVID-19-positive patients, with 21 (84%) patients having a favorable outcome. Out of the 65 COVID-19-positive patients, 4\/25 (16%) had unfavorable outcomes, with one patient (4%) failing TB treatment and two patients (8%) dying. This is the first study from India that studied the occurrence and course of COVID-19 among a large number of TB patients taking anti-TB treatment under programmatic conditions. Due to the similarity in symptoms of TB and certain viral respiratory illnesses, a protocol should be established for healthcare workers to check patients for both illnesses.<\/jats:p>","DOI":"10.4081\/monaldi.2024.3103","type":"journal-article","created":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T03:59:06Z","timestamp":1731038346000},"source":"Crossref","is-referenced-by-count":0,"title":["Clinical profile, risk factors, disease severity, and outcome for COVID-19 disease in patients with tuberculosis on treatment under the National Tuberculosis Elimination Program: a cohort of 1400 patients"],"prefix":"10.4081","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1340-3146","authenticated-orcid":false,"given":"Neeta","family":"Singla","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4538-6926","authenticated-orcid":false,"given":"Amitesh","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9676-9399","authenticated-orcid":false,"given":"U.K.","family":"Khalid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravindra Kumar","family":"Dewan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1806-8831","authenticated-orcid":false,"given":"Rupak","family":"Singla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2549","published-online":{"date-parts":[[2024,11,8]]},"reference":[{"key":"46570","unstructured":"WHO. Global tuberculosis report 2022. Available from: https:\/\/www.who.int\/teams\/global-tuberculosis-programme\/tb-reports\/global-tuberculosis-report-2022."},{"key":"46571","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.02538-2021"},{"key":"46572","unstructured":"WHO. COVID-19 and TB. Available from: https:\/\/www.who.int\/publications\/digital\/global-tuberculosis-report-2021\/covid-19."},{"key":"46573","doi-asserted-by":"publisher","DOI":"10.5588\/ijtld.21.0148"},{"key":"46574","doi-asserted-by":"publisher","DOI":"10.1016\/j.tube.2020.102020"},{"key":"46575","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01398-2020"},{"key":"46576","doi-asserted-by":"publisher","DOI":"10.1016\/j.pulmoe.2020.05.002"},{"key":"46577","unstructured":"Western Cape Department of Health in collaboration with the National Institute for Communicable Diseases, South Africa. Risk factors for coronavirus disease 2019 (COVID-19) death in a population cohort study from the Western Cape province, South Africa. Clin Infect Dis 2021;73:e2005-15."},{"key":"46578","doi-asserted-by":"publisher","DOI":"10.1080\/23744235.2020.1806353"},{"key":"46579","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2001017"},{"key":"46580","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2002032"},{"key":"46581","doi-asserted-by":"publisher","DOI":"10.4081\/monaldi.2020.1294"},{"key":"46582","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01727-2020"},{"key":"46583","unstructured":"WHO. WHO COVID-19 dashboard. Available from: https:\/\/covid19.who.int\/table."},{"key":"46584","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.03408-2020"},{"key":"46585","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.657006"},{"key":"46586","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2008410117"}],"container-title":["Monaldi Archives for Chest Disease"],"original-title":[],"link":[{"URL":"https:\/\/www.monaldi-archives.org\/macd\/article\/download\/3103\/1967","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.monaldi-archives.org\/macd\/article\/download\/3103\/1966","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T09:35:56Z","timestamp":1770197756000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.monaldi-archives.org\/macd\/article\/view\/3103"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,8]]},"references-count":17,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,12,31]]}},"URL":"https:\/\/doi.org\/10.4081\/monaldi.2024.3103","relation":{},"ISSN":["2532-5264","1122-0643"],"issn-type":[{"value":"2532-5264","type":"electronic"},{"value":"1122-0643","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11,8]]}}}