{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T00:44:58Z","timestamp":1792111498119,"version":"4.4.0"},"reference-count":35,"publisher":"PAGEPress Publications","issue":"3","license":[{"start":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T00:00:00Z","timestamp":1750723200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Monaldi Arch Chest Dis"],"abstract":"<jats:p>This study aimed to evaluate the impact of post-COVID syndrome across a multitude of health domains among COVID-19 survivors via comparative analysis in previously hospitalized vs. non-hospitalized patients. A total of 158 adult COVID survivors who had symptoms that continued during post-COVID recovery were included in this prospective observational study. Data on handgrip strength, the 1-minute sit-to-stand test (1-MSTST), radiological scoring (CXR), Medical Research Council (MRC) dyspnea, Fatigue Assessment Scale (FAS), International Physical Activity Questionnaire, Post-COVID-19 Functional Status, Hospital Anxiety-Depression Scale, and Short Form Health Survey 36 (SF-36) health-related quality of life (SF-36 HRQoL) were recorded. Post-COVID 1st-month data revealed dyspnea (MRC scale \u22652 in 57.0% of patients) and fatigue (FAS scores \u226522 in 55.7%), a decrease in handgrip strength (60.0%) and physical activity (60.0%), poor HRQoL (SF-36 general health score \u226450 in 61.4%), and radiological disease progression (CXR score \u22653 in 56.8%) in at least half of patients, along with depression (34.8%) or anxiety (43.7%). Post-COVID 6th-month values for fat-free mass index (p=0.008), 1-MSTST recovery time (p=0.012), and 3rd-month CXR scores (p=0.024) were significantly higher, and 3rd-month SF-36 social functioning domain scores (p=0.026) were significantly lower in previously hospitalized vs. non-admitted patients. In conclusion, our findings indicate a diverse range of impairments in several health domains in COVID-19 survivors, while radiological disease progression and functional limitations were more remarkable in those with previous hospitalization. A comprehensive assessment of health status and persisting rehabilitation needs is necessary in COVID-19 survivors, regardless of disease severity.<\/jats:p>","DOI":"10.4081\/monaldi.2025.3416","type":"journal-article","created":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T03:37:35Z","timestamp":1750736255000},"source":"Crossref","is-referenced-by-count":0,"title":["The impact of post-COVID syndrome across a multitude of health domains: a comparative analysis in previously hospitalized &lt;i&gt;versus&lt;\/i&gt; non-hospitalized COVID-19 survivors"],"prefix":"10.4081","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8724-5331","authenticated-orcid":true,"given":"Elif","family":"Yildirim","sequence":"first","affiliation":[{"name":"Clinic of Chest Diseases, Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital, Health Sciences University, Istanbul"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ipek","family":"Ozmen","sequence":"additional","affiliation":[{"name":"Clinic of Chest Diseases, Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital, Health Sciences University, Istanbul"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0311-114X","authenticated-orcid":true,"given":"Meral","family":"Sahin","sequence":"additional","affiliation":[{"name":"Clinic of Physiotherapy, Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital, Health Sciences University, Istanbul"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8756-691X","authenticated-orcid":true,"given":"Begum","family":"Ozpolat","sequence":"additional","affiliation":[{"name":"Clinic of Physiotherapy, Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital, Health Sciences University, Istanbul"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4870-0597","authenticated-orcid":true,"given":"Ahmet Kursat","family":"Karaman","sequence":"additional","affiliation":[{"name":"Clinic of Radiology, Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital, Health Sciences University, Istanbul"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5962-8332","authenticated-orcid":true,"given":"Emine","family":"Aksoy","sequence":"additional","affiliation":[{"name":"Clinic of Chest Diseases, Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital, Health Sciences University, Istanbul"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2549","published-online":{"date-parts":[[2025,6,24]]},"reference":[{"key":"58453","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.19719"},{"key":"58454","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.12839"},{"key":"58455","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-024-19264-5"},{"key":"58456","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-023-05481-6"},{"key":"58457","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13051457"},{"key":"58458","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2021.02.019"},{"key":"58459","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2021-057246"},{"key":"58460","doi-asserted-by":"publisher","DOI":"10.1111\/jocn.16352"},{"key":"58461","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S115439"},{"key":"58462","doi-asserted-by":"publisher","DOI":"10.1007\/s11547-020-01200-3"},{"key":"58463","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3999(02)00392-6"},{"key":"58464","doi-asserted-by":"publisher","DOI":"10.4103\/nsn.nsn_142_21"},{"key":"58465","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5868-8-115"},{"key":"58466","doi-asserted-by":"publisher","DOI":"10.2466\/06.08.PMS.111.4.278-284"},{"key":"58467","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01494-2020"},{"key":"58468","doi-asserted-by":"publisher","DOI":"10.3906\/sag-2105-125"},{"key":"58469","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1983.tb09716.x"},{"key":"58470","unstructured":"Aydemir O, Guvenir T, Kuey L, Kultur S. 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