{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T11:43:57Z","timestamp":1789559037253,"version":"build-2803163510"},"reference-count":12,"publisher":"PAGEPress Publications","issue":"1","license":[{"start":{"date-parts":[[2021,3,19]],"date-time":"2021-03-19T00:00:00Z","timestamp":1616112000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Med Chir"],"abstract":"<jats:p>Fibrous Dysplasia (FD) is a non-malignant condition caused by post-zygotic, activating mutations of the GNAS gene that results in inhibition of the differentiation and proliferation of bone-forming stromal cells and leads to the replacement of normal bone and marrow by fibrous tissue and woven bone. The clinical behavior and progression of FD is variable. The management of this condition is difficult and in every case is strictly individualized. We report a case of frontal fibrous dysplasia in a 6month\u2019s old boy who underwent a successfully resection of the lesion with an excellent cosmetic effect.<\/jats:p>","DOI":"10.4081\/pmc.2021.225","type":"journal-article","created":{"date-parts":[[2021,3,19]],"date-time":"2021-03-19T08:34:54Z","timestamp":1616142894000},"source":"Crossref","is-referenced-by-count":3,"title":["Frontal bone fibrous dysplasia in a 6-months-old boy: A distinctive entity"],"prefix":"10.4081","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2713-7504","authenticated-orcid":false,"given":"Kleanthis","family":"Anastasiadis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7034-7259","authenticated-orcid":false,"given":"Vassilis","family":"Lambropoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalliopi","family":"Tsoleka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6726-085X","authenticated-orcid":false,"given":"Chrysostomos","family":"Kepertis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7555-1187","authenticated-orcid":false,"given":"Vassilis","family":"Mouravas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis","family":"Spyridakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2549","published-online":{"date-parts":[[2021,3,19]]},"reference":[{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2012.02.016"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e3181edc5af"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1053\/joms.2001.20487"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2008.10.015"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/S0181-5512(05)81011-3"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2009.01.008"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2009.6"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.5334\/jbr-btr.467"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2014.06.012"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.127.10.1239"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19940301)73:5<1411::AID-CNCR2820730516>3.0.CO;2-T"},{"key":"26","doi-asserted-by":"crossref","unstructured":"Tabareau DelalandeF, Collin C, GomezBrouchetA, et al. Diagnostic value of investigating GNAS mutations in fibro-osseous lesions: a retrospective study of 91 cases of fibrous dysplasia and 40 other fibro-osseous lesions. 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