{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T05:30:26Z","timestamp":1780551026810,"version":"3.54.1"},"reference-count":19,"publisher":"PAGEPress Publications","issue":"2","license":[{"start":{"date-parts":[[2022,10,18]],"date-time":"2022-10-18T00:00:00Z","timestamp":1666051200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Med Chir"],"abstract":"<jats:p>Paediatric Intestinal Transplantation (IT) presents the highest mortality on the waiting-list due to anatomical disproportion. Living-Donor IT (LDIT) offers the best advantages and when performed among identical monozygotic twins, it also benefits from unique immunology. According to MEDLINE\/Pubmed, twin-to-twin LDIT has been performed in seven cases (6:7 males, median age of 32 years). None of the patients received immunosuppression postoperatively. Only one paediatric twinto- twin LDIT was carried out with a 160-cm mid-ileum tract: an interposed 4\/5-cm arterial graft was required to ensure a tensionfree anastomosis to the anterior wall of the infra-renal abdominal aorta. In contrast, venous anastomosis was done directly to the inferior cava vein. We present a case for debate of a 13- month-old SBS patient where a twin-LDIT was discussed with parents, who decided to wait after careful analysis and ethical considerations.<\/jats:p>","DOI":"10.4081\/pmc.2022.287","type":"journal-article","created":{"date-parts":[[2022,10,18]],"date-time":"2022-10-18T16:22:25Z","timestamp":1666110145000},"source":"Crossref","is-referenced-by-count":1,"title":["Intestinal twin-to-twin transplant for short gut: Review of the literature and discussion of a complex case"],"prefix":"10.4081","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7150-6082","authenticated-orcid":false,"given":"Sara","family":"Ugolini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo","family":"Coletta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5323-3620","authenticated-orcid":false,"given":"Antonino","family":"Morabito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2549","published-online":{"date-parts":[[2022,10,18]]},"reference":[{"key":"1398","doi-asserted-by":"crossref","unstructured":"Morabito A, Ugolini S, Cianci MC, Coletta R. Current surgical concepts and indications in the management of the short bowel state: A call for the use of multidisciplinary intestinal rehabilitation programs. Children 2021;8:654.","DOI":"10.3390\/children8080654"},{"key":"1399","doi-asserted-by":"crossref","unstructured":"Goulet O, Ruemmele F. Causes and management of intestinal failure in children. Gastroenterology 2006;130:S16-28.","DOI":"10.1053\/j.gastro.2005.12.002"},{"key":"1400","doi-asserted-by":"crossref","unstructured":"Bishay M, Pichler J, Horn V, et al. Intestinal failure-associated liver disease in surgical infants requiring long-term parenteral nutrition. J Pediatr Surg 2012;47:359-62.","DOI":"10.1016\/j.jpedsurg.2011.11.032"},{"key":"1401","doi-asserted-by":"crossref","unstructured":"Yap JYK, Roberts AJ, Bines JE. Paediatric intestinal failure and transplantation. J Paediatr Child Health 2020;56:1747-53.","DOI":"10.1111\/jpc.15052"},{"key":"1402","doi-asserted-by":"crossref","unstructured":"Tzvetanov IG, Tulla KA, D\u2019Amico G, Benedetti E. Living donor intestinal transplantation. Gastroenterol Clin North Am 2018;47:369-80.","DOI":"10.1016\/j.gtc.2018.01.008"},{"key":"1403","doi-asserted-by":"crossref","unstructured":"Gazit VA, Swietlicki EA, Liang MU, et al. Stem cell and niche regulation in human short bowel syndrome. JCI Insight 2020;5:e137905.","DOI":"10.1172\/jci.insight.137905"},{"key":"1404","doi-asserted-by":"crossref","unstructured":"Lauro A, Panaro F, Iyer KR. Analyse de l\u2019activit\u00e9 actuelle de transplantation intestinale en Europe et aux \u00c9tats-Unis. J Visceral Surg 2017;154:105-14.","DOI":"10.1016\/j.jchirv.2016.08.008"},{"key":"1405","doi-asserted-by":"crossref","unstructured":"Celik N, Mazariegos G v., Soltys K, et al. Pediatric intestinal transplantation. 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Four year nutritional follow up after living-related small bowel transplantation between monozygotic twins. Gut 2003;52:659-62.","DOI":"10.1136\/gut.52.5.659"},{"key":"1410","doi-asserted-by":"crossref","unstructured":"Morel P, Kadry Z, Charbonnet P, et al. Paediatric living related intestinal transplantation between two monozygotic twins: A 1-year follow-up. Lancet 2000;355:723-4.","DOI":"10.1016\/S0140-6736(99)05789-X"},{"key":"1411","doi-asserted-by":"crossref","unstructured":"Wu G, Zhao Q, Wang M, et al. Identical twin small-bowel transplantation without maintenance immunosuppression: A 5-year follow-up and literature review. Transplant Direct 2018;4:e374.","DOI":"10.1097\/TXD.0000000000000807"},{"key":"1412","doi-asserted-by":"crossref","unstructured":"Gheza F, di Bella C, Tulla K, et al. Small bowel transplantation in identical twins a video vignette. 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