{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T09:46:29Z","timestamp":1782812789414,"version":"3.54.5"},"reference-count":7,"publisher":"PAGEPress Publications","issue":"1","license":[{"start":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T00:00:00Z","timestamp":1780876800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Med Chir"],"abstract":"<jats:p>Intussusception is a leading cause of intestinal obstruction in young children but remains uncommon in adolescents, where structural lead points typically predominate. Functional or transient small-bowel intussusception without anatomical lesions is rare and often under-recognized in this age group. We report two adolescents presenting with acute abdominal pain and vomiting. Case 1 involved a 15-year-old girl on SSRI therapy with jejuno-ileal intussusception that spontaneously reduced during laparoscopy; localized hematoma, marked hyperperistalsis and venous congestion were observed without structural lead points. Case 2 involved a 13-yearold boy with heterozygous \u03b2-thalassemia and ileo-ileal intussusception associated with reactive mesenteric lymph nodes; laparoscopic reduction was successful. These cases illustrate non-structural mechanisms of adolescent intussusception, including SSRI-associated hypermotility and reactive lymphoid hyperplasia. Recognition of these factors, combined with prompt laparoscopic assessment, ensures optimal management, and prevents ischemic complications.<\/jats:p>","DOI":"10.4081\/pmc.2026.375","type":"journal-article","created":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T10:09:49Z","timestamp":1780913389000},"source":"Crossref","is-referenced-by-count":0,"title":["Beyond lead points: transient small-bowel intussusception in adolescents without structural lesions"],"prefix":"10.4081","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-6120-6751","authenticated-orcid":false,"given":"Eleni","family":"Boutouridou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasiliki","family":"Magaliou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleftheria","family":"Emmanouilidou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fotios","family":"Kazantzidis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evgeniya","family":"Babacheva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kleanthis","family":"Anastasiadis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2549","published-online":{"date-parts":[[2026,6,8]]},"reference":[{"key":"4197","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-023-03961-y"},{"key":"4198","unstructured":"2. Ibrahim D, Patel NP, Gupta M, et al. Ileocecal intussusception in the adult population: case series of two patients. West J Emerg Med 2010;11:197\u2013200."},{"key":"4199","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-024-04717-y"},{"key":"4200","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2006.00792.x"},{"key":"4201","doi-asserted-by":"publisher","DOI":"10.1007\/s13311-023-01362-8"},{"key":"4202","doi-asserted-by":"publisher","DOI":"10.2147\/TCRM.S363404"},{"key":"4203","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2010.04351.x"}],"container-title":["La Pediatria Medica e Chirurgica"],"original-title":[],"link":[{"URL":"https:\/\/www.pediatrmedchir.org\/pmc\/article\/download\/375\/418","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.pediatrmedchir.org\/pmc\/article\/download\/375\/419","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.pediatrmedchir.org\/pmc\/article\/download\/375\/418","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T09:28:28Z","timestamp":1782811708000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.pediatrmedchir.org\/pmc\/article\/view\/375"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,8]]},"references-count":7,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,2,2]]}},"URL":"https:\/\/doi.org\/10.4081\/pmc.2026.375","relation":{},"ISSN":["2420-7748","0391-5387"],"issn-type":[{"value":"2420-7748","type":"electronic"},{"value":"0391-5387","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6,8]]}}}