{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T11:07:30Z","timestamp":1791803250563,"version":"4.3.4"},"reference-count":35,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2010,3,8]],"date-time":"2010-03-08T00:00:00Z","timestamp":1268006400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Reports"],"abstract":"<jats:p>In Nigeria, over 900,000 children under the age of five years die every year. Early neonatal death is responsible for a little over 20% of these deaths. Prematurity remains a significant cause of these early neonatal deaths. In some series, it is reported to be responsible for 60-70% of these deaths. This study aimed to determine the prevalence and determinants of pre-term deliveries at the University of Ilorin Teaching Hospital, Ilorin. This was a prospective cohort study conducted over a 9-month period at the University of Ilorin Teaching Hospital. Records of deliveries and data on maternal socio-biological and antenatal variables were collected during this period in order to determine the prevalence and determinants of pre-term deliveries. Out of the 2,489 deliveries that took place over a 9-month period, there were 293 pre-terms, giving a pre-term delivery rate of 120 per 1,000 deliveries. Of the total deliveries, 1,522 singleton deliveries that satisfied inclusion criteria were recruited; 185 of them were pre-term deliveries giving a case:control ratio of 1:7. Significant determinants of pre-term delivery identified were previous pre-term delivery (P=0.001; OR=3.55; 95% CI=1.71-7.30), antepartum hemorrhage (P=0.000; OR=8.95; 95%CI=4.06-19.78), premature rupture of the membranes (P=0.000; OR=6.48; 95%CI=4.33-9.67), maternal urinary tract infection (P=0.006; OR=5.89; 95%CI=1.16-27.57), pregnancy induced hypertension (P=0.007; OR=3.23; 95%CI=2.09-4.99), type of labor (P=0.000; OR=6.44; 95%CI=4.42-9.38) and booking status (P=0.000; OR=4.67; 95%CI=3.33-6.56). The prevalence of pre-term delivery was 120 per 1,000 live births. Factors significantly associated with pre-term delivery were low socio-economic class, previous pre-term delivery, antepartum hemorrhage, premature rupture of fetal membranes, urinary tract infection, pregnancy induced hypertension, induced labor, and booking elsewhere outside the teaching hospital.<\/jats:p>","DOI":"10.4081\/pr.2010.e3","type":"journal-article","created":{"date-parts":[[2010,3,19]],"date-time":"2010-03-19T08:22:29Z","timestamp":1268986949000},"page":"e3","source":"Crossref","is-referenced-by-count":31,"title":["Prevalence and Determinants of Pre-term Deliveries in the University of Ilorin Teaching Hospital, Ilorin, Nigeria"],"prefix":"10.3390","volume":"2","author":[{"given":"Olugbenga A.","family":"Mokuolu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BM","family":"Suleiman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"OO","family":"Adesiyun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Adeniyi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2010,3,8]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1093\/aje\/154.4.307","article-title":"Trends in preterm birth and neonatal mortality among blacks and white in the United States of America from 1989 to 1997","volume":"154","author":"Demissie","year":"2001","journal-title":"Am J Epidemiol"},{"key":"ref2","first-page":"50","article-title":"Risk factors for neonatal mortality in a regional tertiary hospital in Nigeria","volume":"7","author":"Ezechukwu","year":"2004","journal-title":"Nig J Clin Pract"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1471-0528.2005.00575.x","article-title":"The epidemiology of preterm labour","volume":"112","author":"Steer","year":"2005","journal-title":"Br J Obstet Gynaecol"},{"key":"ref4","series-title":"Neonatology pathophysiology and management of the Newborn","first-page":"264","article-title":"Extreme prematurity","author":"Usher","year":"1987"},{"key":"ref5","first-page":"228","article-title":"Preterm delivery in Ilorin; multiple and teenage pregnancies major aetiologic factors","volume":"12","author":"Chike-Obi","year":"1993","journal-title":"West Afr J Med"},{"key":"ref6","first-page":"155","article-title":"A study of neonatal deaths at the Ogun State University Teaching Hospital, Sagamu, Nigeria","volume":"98","author":"Njokanma","year":"1995","journal-title":"J Trop Paediatr"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1093\/tropej\/40.2.78","article-title":"Perinatal mortality at the Ogun State University Teaching Hospital, Sagamu, Nigeria","volume":"40","author":"Njokanma","year":"1994","journal-title":"J Trop Paediatr"},{"key":"ref8","first-page":"49","article-title":"Limit of fetal viability and its enhancement","volume":"5","author":"Breborowicz","year":"2001","journal-title":"Early Pregnancy"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1053\/sper.2001.27164","article-title":"The outcome of extreme prematurity","volume":"25","author":"Lorenz","year":"2001","journal-title":"Semin Perinatol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1056\/NEJM199311253292201","article-title":"The limit of viability-neonatal outcome of infants born at 22 to 25 weeks gestation","volume":"329","author":"Allen","year":"1993","journal-title":"N Engl J Med"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/S0140-6736(84)90943-7","article-title":"Capable of being born alive?","volume":"1","author":"Dunn","year":"1984","journal-title":"Lancet"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1177\/004947550403400315","article-title":"Maternal and neonatal profile and immediate outcome in extremely low birthweight babies in Delhi","volume":"34","author":"Sehgal","year":"2004","journal-title":"Trop Doct"},{"key":"ref13","first-page":"27","article-title":"Epidemiology of preterm delivery in Benin City","volume":"23","author":"Ibhanesebhor","year":"1996","journal-title":"Nig J Paediatr"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"32","DOI":"10.4314\/tjog.v19i1.14366","article-title":"Maternal factors associated with early spontaneous singleton preterm delivery in Nigeria","volume":"19","author":"Mokuolu","year":"2002","journal-title":"Trop J Obstet Gynaecol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/0895-4356(95)00566-8","article-title":"Determinants of preterm delivery in low risk pregnancies. 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