{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,4]],"date-time":"2025-05-04T18:22:20Z","timestamp":1746382940245},"reference-count":15,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2012,1,17]],"date-time":"2012-01-17T00:00:00Z","timestamp":1326758400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Reports"],"abstract":"<jats:p>Community-acquired methicillin-resistant Staphylococcus aureus has become a wellestablished pathogen with alarming rates during the last decade. The current situation of this bacteria in pediatric infections is very limited and motivated us to conduct this study. This is a retrospective and analytical study including patients less than 18 years of age with the diagnosis of skin or soft tissue infections in 2008 and 2009 meeting the criteria of Community-acquired infection. A prevalence of 41.9% among skin and soft tissue infections was found. Inducible resistance to clindamycin was detected in 1.3% of the strains and the infection shows a seasonal predilection for summer (P=0.003); 57.8% of the cases required hospitalization with a mean stay of 3.3\u00b12.5 days. The susceptibility to clindamycin and co-trimoxazole is 88 and 97% respectively. The resistance to erythromycin has reached 92%. The main diagnoses at presentation was gluteal abscess plus cellulitis (34.2%). The prevalence of CA-MRSA is trending up and seems to become a large burden for the health system in our community. Clindamycin is still an excellent option in the community setting since inducible clindamycin resistance is extremely low in this community. Co-trimoxazole should be kept as a reserved drug to avoid the rapid resurgence resistance in the community.<\/jats:p>","DOI":"10.4081\/pr.2012.e5","type":"journal-article","created":{"date-parts":[[2012,1,18]],"date-time":"2012-01-18T14:57:59Z","timestamp":1326898679000},"page":"e5","source":"Crossref","is-referenced-by-count":6,"title":["Current Role of Community-Acquired Methicillin-Resistant Staphylococcus Aureus among Children with Skin and Soft Tissue Infections"],"prefix":"10.3390","volume":"4","author":[{"given":"Carlos 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aureus","volume":"26","author":"Thomas","year":"2008","journal-title":"Emerg Med Clin N Am"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3201\/eid0501.990102","article-title":"The economic impact of Staphylococcus aureus infection in New York City hospitals","volume":"5","author":"Rubin","year":"1999","journal-title":"Emerg Infect Dis"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1086\/430312","article-title":"Three-year surveillance of community-acquired Staphylococcus aureus infections in children","volume":"40","author":"Kaplan","year":"2005","journal-title":"Clin Infect Dis"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1097\/INF.0b013e318124aa5c","article-title":"No decrease in clindamycin susceptibility despite increased use of clindamycin for pediatric community-associated methicillin-resistant Staphylococcus aureus skin 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