{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:26:07Z","timestamp":1763036767918},"reference-count":10,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2013,6,13]],"date-time":"2013-06-13T00:00:00Z","timestamp":1371081600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Reports"],"abstract":"<jats:p>There is a well-known correlation between Herpes simplex (HSV) infection and erythema multiforme (EM). More recently, in Japan, it was found that Chlamydia pneumoniae (Cp) may promote the development of EM. All cases of Cp infection-associated EM that had been diagnosed in our clinic over the past two years (from 2011 to 2012) were analyzed. Cp infection was diagnosed on the basis of a significant increase (&gt;2.00) in anti-Cp IgM titers, as measured by the HITAZYME-ELISA test. There were 7 cases of Cp-EM, one male and 6 females. Median age was 13 years (range 3-29 years). It is recommended that the possible involvement of Cp infection, besides HSV or Mycoplasma pneumoniae infections, should be considered in all cases of EM.<\/jats:p>","DOI":"10.4081\/pr.2013.e9","type":"journal-article","created":{"date-parts":[[2013,6,13]],"date-time":"2013-06-13T13:14:15Z","timestamp":1371129255000},"page":"e9","source":"Crossref","is-referenced-by-count":13,"title":["Chlamydia Pneumoniae Infection-Associated Erythema Multiforme"],"prefix":"10.3390","volume":"5","author":[{"given":"Shinsaku","family":"Imashuku","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoko","family":"Kudo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2013,6,13]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1097\/00007611-198606000-00027","article-title":"Erythema multiforme due to herpes simplex: treatment with oral acyclovir","volume":"79","author":"Goldberg","year":"1986","journal-title":"South Med J"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0190-9622(88)70027-4","article-title":"Acyclovir for recurrent erythema multiforme caused by herpes simplex","volume":"18","author":"Huff","year":"1988","journal-title":"J Am Acad Dermatol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1111\/j.1365-2133.1993.tb00232.x","article-title":"Recurrent erythema multiforme: clinical features and treatment in a large series of patients","volume":"128","author":"Schofield","year":"1993","journal-title":"Br J Dermatol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1001\/archpedi.1997.02170470048009","article-title":"Herpes simplex virus-associated erythema multiforme in prepubertal children","volume":"151","author":"Weston","year":"1997","journal-title":"Arch Pediatr Adolesc"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1111\/j.1525-1470.2006.00307.x","article-title":"Erythema multiforme due to Mycoplasma pneumoniae infection in two children","volume":"23","author":"Schalock","year":"2006","journal-title":"Pediatr Dermatol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"e1605","DOI":"10.1542\/peds.2010-2624","article-title":"Stevens-Johnson syndrome in a boy with macrolide-resistant Mycoplasma pneumoniae pneumonia","volume":"127","author":"Atkinson","year":"2011","journal-title":"Pediatrics"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1111\/j.1346-8138.2011.01319.x","article-title":"Two cases of erythema exsudativum multiforme associated with Chlamydia pneumoniae infection","volume":"39","author":"Hosokawa","year":"2012","journal-title":"J Dermatol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.11150\/kansenshogakuzasshi1970.70.1176","article-title":"[Double infection of Chlamydia pneumoniae and Mycoplasma pneumoniae in children]","volume":"70","author":"Terada","year":"1996","journal-title":"Kansenshogaku Zasshi"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1007\/s10156-011-0327-x","article-title":"The validity of the criteria for primary infection of Chlamydophila pneumoniae in children by measuring ELISA IgM antibodies","volume":"18","author":"Kamata","year":"2012","journal-title":"J Infect Chemother"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"693","DOI":"10.3109\/00365548909021699","article-title":"Erythema nodosum-a manifestation of Chlamydia pneumoniae (strain TWAR) infection","volume":"21","author":"Erntell","year":"1989","journal-title":"Scand J Infect Dis"}],"container-title":["Pediatric Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.pagepress.org\/journals\/index.php\/pr\/article\/viewFile\/4586\/3967","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.pagepress.org\/journals\/index.php\/pr\/article\/viewFile\/4586\/5587","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.mdpi.com\/2036-7503\/5\/2\/e9\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,10]],"date-time":"2022-02-10T03:38:50Z","timestamp":1644464330000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2036-7503\/5\/2\/e9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6,13]]},"references-count":10,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2013,6]]}},"alternative-id":["pr.2013.e9"],"URL":"https:\/\/doi.org\/10.4081\/pr.2013.e9","relation":{},"ISSN":["2036-7503"],"issn-type":[{"value":"2036-7503","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6,13]]}}}