{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T14:53:06Z","timestamp":1791816786432,"version":"4.3.4"},"reference-count":9,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2016,3,31]],"date-time":"2016-03-31T00:00:00Z","timestamp":1459382400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Reports"],"abstract":"<jats:p>Mycoplasma pneumoniae is a common cause of respiratory infections in children, but sometimes extra-pulmonary diseases can be observed. The immunological mechanisms involved in these extra-respiratory complications are unknown. Here, we report a small case series of Mycoplasma-related diseases including 5 children who developed: i) aseptic meningitis; ii) urticarial rash and pericardial effusion; iii) pleural effusion with severe eosinophilia; iv) Stevens-Johnson syndrome; v) multiform erythema. Interestingly, all children were moderately to highly atopic, as a common immunologic feature.<\/jats:p>","DOI":"10.4081\/pr.2016.6395","type":"journal-article","created":{"date-parts":[[2016,3,31]],"date-time":"2016-03-31T09:19:12Z","timestamp":1459415952000},"page":"6395","source":"Crossref","is-referenced-by-count":33,"title":["Is There Any Relationship Between Extra-Pulmonary Manifestations of Mycoplasma Pneumoniae Infection and Atopy\/Respiratory Allergy in Children?"],"prefix":"10.3390","volume":"8","author":[{"given":"Dimitri","family":"Poddighe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gian Luigi","family":"Marseglia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2016,3,31]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/S1473-3099(01)00147-5","article-title":"Emerging role of Mycoplasma pneumoniae and Chlamydia pneumoniae in paediatric respiratory tract infections","volume":"1","author":"Principi","year":"2001","journal-title":"Lancet Infect Dis"},{"key":"ref2","first-page":"113","article-title":"Unusual manifestations of infections due to Mycoplasma pneumoniae in children","volume":"2","author":"Timitilli","year":"2004","journal-title":"Infez Med"},{"key":"ref3","author":"Capuano","journal-title":"New Liaison\u00ae automated immunoassays for the detection of mycoplasma pneumoniae IgG and IgM antibodies in human serum\/plasma specimens"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1097\/INF.0b013e3182862ea8","article-title":"Asthmatic children have increate specific anti-Mycoplasma pneumoniae IgM but not IgG or IgE-values independent of history of respiratory tract infection","volume":"32","author":"Smith-Norowitz","year":"2013","journal-title":"Pediatr Infect Dis J"},{"key":"ref5","first-page":"986527","article-title":"Mycoplasma pneumoniae infection in children is a risk factor for developing allergic diseases","author":"Ye","year":"2014","journal-title":"World Sci J"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.idc.2009.10.006","article-title":"Mycoplasma pneumonia and its complications","volume":"24","author":"Smith","year":"2010","journal-title":"Infect Dis Clin N Am"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"159","DOI":"10.3109\/02770908709070932","article-title":"Total and specific IgE resp[onses in the acute and recovery phases of respiratory infections in children","volume":"24","author":"Nagayama","year":"1987","journal-title":"J Asthma"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1542\/peds.107.3.e39","article-title":"Bronchoalveolar lavage fluid from patients with micoplasma pneumonia: implication of tendency toward increate immunoglobulin E production","volume":"107","author":"Koh","year":"2001","journal-title":"Pediatrics"},{"key":"ref9","first-page":"1246","article-title":"Humoral and cellular immunity in children with Mycoplasma pneumoniae infection: a 1 year prospective study","volume":"12","author":"Stelmach","year":"2005","journal-title":"Clin Diag Lab Immunol"}],"container-title":["Pediatric Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.pagepress.org\/journals\/index.php\/pr\/article\/viewFile\/6395\/5664","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.mdpi.com\/2036-7503\/8\/1\/6395\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,10]],"date-time":"2022-02-10T03:51:30Z","timestamp":1644465090000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2036-7503\/8\/1\/6395"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,31]]},"references-count":9,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2016,3]]}},"alternative-id":["pr.2016.6395"],"URL":"https:\/\/doi.org\/10.4081\/pr.2016.6395","relation":{},"ISSN":["2036-7503"],"issn-type":[{"value":"2036-7503","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,31]]}}}