{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T14:24:23Z","timestamp":1761920663153},"reference-count":0,"publisher":"PAGEPress Publications","issue":"3","license":[{"start":{"date-parts":[[2019,10,24]],"date-time":"2019-10-24T00:00:00Z","timestamp":1571875200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reumatismo"],"abstract":"<jats:p>Beh\u00e7et\u2019s disease is a chronic autoinflammatory disorder that usually presents with recurrent oral and genital ulcers, uveitis, skin lesions and arthritis. Any organ, however, can be involved and in a subgroup of patients the large vascular lesions are the predominant feature (vasculo-Beh\u00e7et disease). We report a case of a 27-yearold man with Beh\u00e7et\u2019s disease who developed Budd-Chiari syndrome while on immunosuppressive therapy. Infliximab resulted in a rapid and total clinical remission. Literature data have shown that antitumor necrosis factor alpha (anti-TNF-\u03b1) agents including infliximab can suppress disease activity but there is no long-term experience on tapering and\/or discontinuation of treatment under clinical remission. Our case supports the use of infliximab in vasculo-Beh\u00e7et patients.<\/jats:p>","DOI":"10.4081\/reumatismo.2019.1153","type":"journal-article","created":{"date-parts":[[2019,10,24]],"date-time":"2019-10-24T15:16:30Z","timestamp":1571930190000},"page":"163-165","source":"Crossref","is-referenced-by-count":5,"title":["Infliximab in the treatment of Budd-Chiari syndrome in Beh\u00e7et\u2019s disease"],"prefix":"10.4081","volume":"71","author":[{"given":"L.B.","family":"Santos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Rigueira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.P.","family":"Vilas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2549","published-online":{"date-parts":[[2019,10,24]]},"container-title":["Reumatismo"],"original-title":[],"link":[{"URL":"https:\/\/reumatismo.org\/index.php\/reuma\/article\/download\/1153\/851","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/reumatismo.org\/index.php\/reuma\/article\/download\/1153\/851","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,16]],"date-time":"2020-04-16T00:17:28Z","timestamp":1586996248000},"score":1,"resource":{"primary":{"URL":"https:\/\/reumatismo.org\/index.php\/reuma\/article\/view\/1153"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,24]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2019,10,24]]}},"URL":"https:\/\/doi.org\/10.4081\/reumatismo.2019.1153","relation":{},"ISSN":["2240-2683","0048-7449"],"issn-type":[{"value":"2240-2683","type":"electronic"},{"value":"0048-7449","type":"print"}],"subject":[],"published":{"date-parts":[[2019,10,24]]}}}