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All patients had clinical and radiological findings consistent with breast cancer and underwent mastectomy, which is not indicated in PBL. Diagnosis should be established prior to operative interventions, as fine needle aspiration missed the diagnosis for one patient and intra-operative frozen sections for 3 patients in our study. Five-year and 10-year overall survivals were 57% and 15%, respectively. Of the 3 patients who died from PBL, 2 had tumors that were Bcl-2 positive but Bcl-6 negative. All 3 surviving patients have positive Bcl-2 and Bcl-6 immunostaining, which could be important prognostic factors if confirmed by a larger study.<\/jats:p>","DOI":"10.4081\/rt.2009.e14","type":"journal-article","created":{"date-parts":[[2009,8,1]],"date-time":"2009-08-01T09:31:34Z","timestamp":1249119094000},"page":"36-41","source":"Crossref","is-referenced-by-count":15,"title":["Primary Breast Lymphomas"],"prefix":"10.1177","volume":"1","author":[{"given":"Olivier","family":"Julen","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics, Geneva University Hospital, Gen\u00e8ve, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilaria","family":"Dellacasa","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Geneva University Hospital, Gen\u00e8ve, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie-Fran\u00e7oise","family":"Pelte","sequence":"additional","affiliation":[{"name":"Department of Pathology and Immunology, Geneva University Hospital, Gen\u00e8ve, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bettina","family":"Borish","sequence":"additional","affiliation":[{"name":"Department of Pathology and Immunology, Geneva University Hospital, Gen\u00e8ve, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Bouchardy","sequence":"additional","affiliation":[{"name":"Geneva Cancer Registry, Institute for Social and Preventive Medicine, University of Geneva, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federica","family":"Capanna","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Geneva University Hospital, Gen\u00e8ve, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georges","family":"Vlastos","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Geneva University Hospital, Gen\u00e8ve, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Bernard","family":"Dubuisson","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Geneva University Hospital, Gen\u00e8ve, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne-Th\u00e9r\u00e8se","family":"Vlastos","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Geneva University Hospital, Gen\u00e8ve, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2009,7,1]]},"reference":[{"key":"bibr1-rt.2009.e14","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198702000-00008"},{"key":"bibr2-rt.2009.e14","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197206)29:6<1705::AID-CNCR2820290640>3.0.CO;2-I"},{"key":"bibr3-rt.2009.e14","unstructured":"BouchardyC. 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