{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T15:05:48Z","timestamp":1790175948505,"version":"4.1.0"},"reference-count":0,"publisher":"Institute of Hematology, Catholic University","issue":"1","license":[{"start":{"date-parts":[[2020,8,29]],"date-time":"2020-08-29T00:00:00Z","timestamp":1598659200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mediterr J Hematol Infect Dis"],"abstract":"<jats:p>Background\r\nPhysical and psychological factors, like wrong attitudes and behaviours, can negatively influence health outcomes of the patients receiving allogeneic hematopoietic stem cell transplantation (AHSCT). Educational interventions aiming to improve knowledge on side effects, risks, complications and preventive behaviour can reduce psychological distress, and improve quality of life (QoL). We aimed to compare a standard approach with therapeutic patient education (TPE) to analyse the impact on AHSCT patients\u2019 QoL, psychological distress and knowledge of AHSCT side effects, risks complications and preventive behaviour.\r\nMaterial and methods\r\nA prospective interventional study was conducted analysing data of 36 patients who received one of two different educational approaches, which were a standard approach (not-exposed) or TPE (exposed).\r\nResults\r\nIn the exposed group QoL improved 14 days after transplantation (42.2 vs 25.6; p&lt;0.03) and at time of discharge (36.6 vs 54.4; p&lt;0.005). Anxiety and depression was better controlled in the exposed group, both at hospitalization and discharge (anxiety: 48.1 vs 53.2; 46.4 vs 51.6. p&lt;0.04; depression: 49 vs 55.3; 48 vs 54.3 , p&lt;0.03). Knowledge of AHSCT risks and complications improved in exposed patients, both at admission (10.1\/15 vs 8\/15 correct answers; p&lt;0.01) and discharge (10.7\/15 vs 8.8\/15 correct answer; p&lt;0.03).\r\nConclusion\r\nThe TPE for AHSCT patients improved knowledge, reduced anxiety and depression, which consequently increasing QoL. Therefore, we recommend our approach to further engage patients in the treatment plan, which should specifically take place prior to AHSCT initiation.<\/jats:p>","DOI":"10.4084\/mjhid.2020.067","type":"journal-article","created":{"date-parts":[[2020,8,29]],"date-time":"2020-08-29T15:40:41Z","timestamp":1598715641000},"page":"e2020067","source":"Crossref","is-referenced-by-count":18,"title":["Impact of educational interventions on psychological distress during allogeneic hematopoietic stem cell transplantation: a randomized study."],"prefix":"10.4084","volume":"12","author":[{"given":"Marco","family":"Cioce","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franziska Michaela","family":"Lohmeyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rossana","family":"Moroni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marinella","family":"Magini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Giraldi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Garau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Carola","family":"Gifuni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vezio","family":"Savoia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danilo","family":"Celli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Botti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianpaolo","family":"Gargiulo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Bonifazi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Ciceri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivana","family":"Serra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Zega","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona","family":"Sica","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Bacigalupo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerio","family":"De Stefano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umberto","family":"Moscato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2554","published-online":{"date-parts":[[2020,8,29]]},"container-title":["Mediterranean Journal of Hematology and Infectious Diseases"],"original-title":[],"link":[{"URL":"http:\/\/www.mjhid.org\/index.php\/mjhid\/article\/download\/2020.067\/3836","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.mjhid.org\/index.php\/mjhid\/article\/download\/2020.067\/3836","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,29]],"date-time":"2020-08-29T15:40:42Z","timestamp":1598715642000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.mjhid.org\/index.php\/mjhid\/article\/view\/2020.067"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,29]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,1,1]]}},"URL":"https:\/\/doi.org\/10.4084\/mjhid.2020.067","relation":{},"ISSN":["2035-3006"],"issn-type":[{"value":"2035-3006","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,29]]}}}