{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T07:59:09Z","timestamp":1787731149787,"version":"build-2784847793"},"reference-count":0,"publisher":"Hematology Section, Dept. of Radiological Science and Hematology, Catholic University, Rome, Italy","issue":"1","license":[{"start":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T00:00:00Z","timestamp":1745971200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mediterr J Hematol Infect Dis"],"abstract":"<jats:p>Chronic myeloid leukemia (CML) is a hematologic malignancy characterized by an uncontrolled proliferation of myeloid cells, particularly neutrophils. It is revealed through the detection of a Philadelphia chromosome (BCR;ABL).\nWhile tyrosine kinase inhibitors have dramatically improved short and middle-term outcomes, in some resistant or relapsing cases, allogeneic hematopoietic stem cell transplantation (HSCT) can be a curative option. \nIn this\u00a0first-ever documented case, we report the successful use of\u00a0fecal microbiota transplantation (FMT) to treat both corticosteroid-resistant gastrointestinal GvHD and concomitant cryptosporidiosis, leading to significant clinical improvement in a patient post umbilical cord blood HSCT.<\/jats:p>","DOI":"10.4084\/mjhid.2025.035","type":"journal-article","created":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T09:45:12Z","timestamp":1746092712000},"page":"e2025035","source":"Crossref","is-referenced-by-count":2,"title":["Fecal microbiota transplantation as a salvage therapy for concomitant resistant digestive graft versus host disease and cryptosporidiosis in a patient post hematopoietic stem cell transplant : about a case"],"prefix":"10.4084","volume":"17","author":[{"given":"Thomas","family":"Finotto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carole","family":"Chevenet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amandine","family":"Fayard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2554","published-online":{"date-parts":[[2025,4,30]]},"container-title":["Mediterranean Journal of Hematology and Infectious Diseases"],"original-title":[],"link":[{"URL":"https:\/\/www.mjhid.org\/mjhid\/article\/download\/5957\/4690","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.mjhid.org\/mjhid\/article\/download\/5957\/4695","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.mjhid.org\/mjhid\/article\/download\/5957\/4690","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T10:21:39Z","timestamp":1746440499000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mjhid.org\/mjhid\/article\/view\/5957"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,30]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,1,1]]}},"URL":"https:\/\/doi.org\/10.4084\/mjhid.2025.035","relation":{},"ISSN":["2035-3006"],"issn-type":[{"value":"2035-3006","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,30]]}}}