{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T17:58:46Z","timestamp":1775584726626,"version":"3.50.1"},"reference-count":31,"publisher":"National Athletic Trainers' Association","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:p>\n          <jats:bold>Context:<\/jats:bold> Fatigue could contribute to ankle-sprain injuries during sport, particularly for individuals with chronic ankle instability (CAI).<\/jats:p>\n        <jats:p>\n          <jats:bold>Objective:<\/jats:bold> To examine whether adults with or without CAI develop fatigue at similar rates when performing ankle exercises at the same relative effort level and whether these groups differ in their subjective perceptions of fatigue.<\/jats:p>\n        <jats:p>\n          <jats:bold>Design:<\/jats:bold> Controlled laboratory study.<\/jats:p>\n        <jats:p>\n          <jats:bold>Setting:<\/jats:bold> Biomechanics research laboratory.<\/jats:p>\n        <jats:p>\n          <jats:bold>Patients or Other Participants:<\/jats:bold> A total of 11 volunteers with CAI (1 man, 10 women; age = 23.5 \u00b1 3.0 years, height = 168.0 \u00b1 11.2 cm, mass = 64.3 \u00b1 13.5 kg) were recruited for the unstable-ankle group, and 11 volunteers matched for age, height, mass, and sex (1 man, 10 women; age = 24.1 \u00b1 2.1 years, height = 169.5 \u00b1 9.7 cm, mass = 62.3 \u00b1 9.7 kg) were recruited as control participants.<\/jats:p>\n        <jats:p>\n          <jats:bold>Intervention(s):<\/jats:bold> Localized muscle fatigue (LMF) was induced in the ankle of the dominant limb using a custom fatigue protocol. Plantar-flexion and dorsiflexion exertions were completed at a rate of 12 cycles per minute at isotonic loads equal to 70% and 30%, respectively, of individual maximal voluntary isometric strength. Intermittent measures of maximal voluntary isometric strength and ratings of perceived exertion (RPEs) were obtained.<\/jats:p>\n        <jats:p>\n          <jats:bold>Main Outcome Measure(s):<\/jats:bold> We compared isometric-strength measures and RPE scores at each observation time (prefatigue and at 4, 8, 12, and 16 minutes into the fatigue protocol) and the group correlations between changes in strength and changes in RPE scores.<\/jats:p>\n        <jats:p>\n          <jats:bold>Results:<\/jats:bold> Based on ankle-strength measures, the 2 test groups developed LMF at similar rates when exercising at equivalent levels of relative effort. The 2 groups also reported similar levels of discomfort as fatigue progressed.<\/jats:p>\n        <jats:p>\n          <jats:bold>Conclusions:<\/jats:bold> The rate of LMF development at the ankle and the associated perception of fatigue did not differ between adults with or without CAI.<\/jats:p>","DOI":"10.4085\/1062-6050-51.9.02","type":"journal-article","created":{"date-parts":[[2016,9,19]],"date-time":"2016-09-19T17:41:56Z","timestamp":1474306916000},"page":"491-497","source":"Crossref","is-referenced-by-count":12,"title":["Localized Ankle Fatigue Development and Fatigue Perception in Adults With or Without Chronic Ankle Instability"],"prefix":"10.4085","volume":"51","author":[{"given":"Courtney A.","family":"Webster","sequence":"first","affiliation":[{"name":"School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Blacksburg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maury A.","family":"Nussbaum","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Blacksburg"},{"name":"Department of Industrial Systems and Engineering, Virginia Polytechnic Institute and State University, Blacksburg"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2557","reference":[{"key":"i1062-6050-51-6-491-b01","series-title":"National Health Interview Survey, 2012 Data Release. 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Chronic ankle instability: biomechanics and pathomechanics of ligaments injury and associated lesions","volume":"96","author":"Bonnel \n              F,","year":"2010","unstructured":"Bonnel \n              F, \n            \n            \n              Toullec \n              E, \n            \n            \n              Mabit \n              C, \n            \n            \n              Tourne \n              Y; \n            \n          \n          SOFCOT. Chronic ankle instability: biomechanics and pathomechanics of ligaments injury and associated lesions. 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J Biomech. 2013;46(1):175\u2013178."},{"key":"i1062-6050-51-6-491-b10","series-title":"Proprioception and Neuromuscular Control in Joint Stability","first-page":"237","article-title":"Proprioception and sensorimotor control in the functionally unstable ankle","author":"Konradsen \n              L,","year":"2000","unstructured":"Konradsen \n              L, \n            \n            \n              Beynnon \n              B, \n            \n            \n              Renstrom \n              PA. \n            \n          \n          Proprioception and sensorimotor control in the functionally unstable ankle. In: Lephart SM, Fu FH, eds. Proprioception and Neuromuscular Control in Joint Stability. 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Br J Sports Med. 2011;45(8):660\u2013672."},{"issue":"4","key":"i1062-6050-51-6-491-b14","series-title":"J Athl Train","first-page":"394","article-title":"Factors contributing to chronic ankle instability: a strength perspective","volume":"37","author":"Kaminski \n              TW,","year":"2002","unstructured":"Kaminski \n              TW, \n            \n            \n              Hartsell \n              HD. \n            \n          \n          Factors contributing to chronic ankle instability: a strength perspective. J Athl Train. 2002;37(4):394\u2013405."},{"issue":"10","key":"i1062-6050-51-6-491-b15","series-title":"Med Sci Sports Exerc","first-page":"1774","article-title":"Modulation of prelanding lower-limb muscle responses in athletes with multiple ankle sprains","volume":"39","author":"Fu \n              SN,","year":"2007","unstructured":"Fu \n              SN, \n            \n            \n              Hui-Chan \n              CW. \n            \n          \n          Modulation of prelanding lower-limb muscle responses in athletes with multiple ankle sprains. 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Med Sci Sports Exerc. 2002;34(1):117\u2013122."},{"issue":"4","key":"i1062-6050-51-6-491-b17","series-title":"Am J Sports Med","first-page":"824","article-title":"Effects of fatigue due to contraction of evertor muscles on the ankle joint position sense in male soccer players","volume":"38","author":"Mohammadi \n              F,","year":"2010","unstructured":"Mohammadi \n              F, \n            \n            \n              Roozdar \n              A. \n            \n          \n          Effects of fatigue due to contraction of evertor muscles on the ankle joint position sense in male soccer players. Am J Sports Med. 2010;38(4):824\u2013828."},{"issue":"1","key":"i1062-6050-51-6-491-b18","series-title":"Physics Int","first-page":"22","article-title":"The effects of fatigue and chronic ankle instability on dynamic postural control","volume":"1","author":"Hosseinimehr \n              SH,","year":"2010","unstructured":"Hosseinimehr \n              SH, \n            \n            \n              Daneshmandi \n              H, \n            \n            \n              Norasteh \n              AA. \n            \n          \n          The effects of fatigue and chronic ankle instability on dynamic postural control. 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