{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T10:35:53Z","timestamp":1755599753988,"version":"3.37.3"},"reference-count":19,"publisher":"Korean Diabetes Association","issue":"1","license":[{"start":{"date-parts":[[2021,7,6]],"date-time":"2021-07-06T00:00:00Z","timestamp":1625529600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["e-dmj.org"],"crossmark-restriction":true},"short-container-title":["Diabetes Metab J"],"published-print":{"date-parts":[[2022,1,31]]},"abstract":"<jats:p>Insulin replacement in type 1 diabetes mellitus (T1DM) needs intensified treatment, which can either be performed by multiple daily injections (MDI) or continuous subcutaneous insulin infusion (CSII). This retrospective analysis of a real-world scenario aimed to evaluate whether glycaemic and cardiovascular risk factors could be controlled with CSII outclass MDI as suggested by recent evidence. Data from patients with either insulin pump (n=68) or injection (n=224) therapy at an Austrian tertiary care centre were analysed between January 2016 and December 2017. There were no significant differences with regard to the latest glycosylated hemoglobin, cardiovascular risk factor control or diabetes-associated late complications. Hypoglycaemia was less frequent (P&lt;0.001), sensor-augmented therapy was more common (P=0.003) and mean body mass index (BMI) was higher (P=0.002) with CSII treatment. This retrospective analysis of real-world data in T1DM did not demonstrate the superiority of insulin pump treatment with regard to glycaemic control or cardiovascular risk factor control.<\/jats:p>","DOI":"10.4093\/dmj.2020.0267","type":"journal-article","created":{"date-parts":[[2021,7,6]],"date-time":"2021-07-06T23:41:00Z","timestamp":1625614860000},"page":"149-153","update-policy":"https:\/\/doi.org\/10.4093\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Real-World Analysis of Therapeutic Outcome in Type 1 Diabetes Mellitus at a Tertiary Care Center"],"prefix":"10.4093","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5578-3650","authenticated-orcid":true,"given":"Antonia","family":"Kietaibl","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6233-1823","authenticated-orcid":true,"given":"Michaela","family":"Riedl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3079-9226","authenticated-orcid":true,"given":"Latife","family":"Bozkurt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2567","reference":[{"first-page":"894","volume-title":"Effect of intensive diabetes management on macrovascular events and risk factors in the Diabetes Control and Complications Trial","year":"1995","key":"ref1"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa052187"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1056\/nejm199309303291401"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2020.0019"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1038\/s41574-018-0044-y"},{"key":"ref6","first-page":"700","volume-title":"Effect of initiating use of an insulin pump in adults with type 1 diabetes using multiple daily insulin injections and continuous glucose monitoring (DIAMOND): a multicentre, randomised controlled trial","author":"Beck","year":"2017"},{"key":"ref7","first-page":"765","volume-title":"Severe hypoglycaemia and glycaemic control in type 1 diabetes: meta-analysis of multiple daily insulin injections compared with continuous subcutaneous insulin infusion","author":"Pickup","year":"2008"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2005.7.876"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1515\/jpem.2003.16.3.393"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1542\/peds.112.3.559"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-157-5-201209040-00508"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0153033"},{"volume-title":"","key":"ref13"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.25.11.2074"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s00592-019-01326-5"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2018.0252"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.cd005103.pub2"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1056\/nejmsb1609216"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1111\/pedi.12754"}],"container-title":["Diabetes &amp; 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