{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T15:48:12Z","timestamp":1785426492020,"version":"3.56.0"},"reference-count":35,"publisher":"The Korean Society of Anesthesiologists","issue":"4","license":[{"start":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T00:00:00Z","timestamp":1776902400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["ekja.org"],"crossmark-restriction":true},"short-container-title":["Korean J Anesthesiol"],"published-print":{"date-parts":[[2026,8,1]]},"abstract":"<jats:p>Background: Intraoperative hypotension (IOH) is common during liver transplantation (LT); however, its impact on long-term mortality remains unclear. We investigated the association between IOH and 1-year mortality using various mean arterial pressure (MAP) thresholds and exposure durations.  Methods: This retrospective observational cohort study included 1063 patients who underwent LT.  We defined IOH as an MAP &lt; 65 mmHg and examined each threshold in 5 mmHg increments to &lt; 40 mmHg. Our primary outcome was 1-year mortality after LT. Multivariate logistic regression was used to control for confounding variables while assessing the association between IOH and 1-year mortality.  Results: The 1-year mortality after LT was 7.1%. Only moderate-to-severe IOH showed independent associations with 1-year mortality: MAP &lt; 55 mmHg for \u2265 43 minutes (hazard ratio [HR] = 2.48, 95% CI [1.05\u20135.86], P = 0.038), MAP &lt; 50 mmHg for \u2265 14 min (HR = 2.60, 95% CI [1.01\u20136.65], P = 0.047), MAP &lt; 45 mmHg for \u2265 13 min (HR = 4.98, 95% CI [1.18\u201321.0], P = 0.029), and MAP &lt; 40 mmHg for \u2265 5 min (HR = 6.72, 95% CI [1.56\u201328.9], P = 0.010), whereas longer exposure durations at MAP &lt; 65 or &lt; 60 mmHg were not independently associated with increased mortality. Furthermore, both a lower MAP and longer exposure duration for each threshold increased the predicted probability of 1-year mortality.Conclusions: Moderate-to-severe hypotension was independently associated with increased 1-year mortality after LT. These findings underscore the importance of intraoperative blood pressure management in LT recipients.<\/jats:p>","DOI":"10.4097\/kja.25965","type":"journal-article","created":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T07:45:59Z","timestamp":1776930359000},"page":"414-425","update-policy":"https:\/\/doi.org\/10.4097\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Intraoperative hypotension during liver transplantation is associated with long-term 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