{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T10:47:05Z","timestamp":1785408425821,"version":"3.56.0"},"reference-count":18,"publisher":"AOSIS","issue":"1","license":[{"start":{"date-parts":[[2024,4,23]],"date-time":"2024-04-23T00:00:00Z","timestamp":1713830400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Very little is known about the diagnostic performance of the American Diabetes Association glycated haemoglobin (HbA1c) cut-off of 6.5% in resource-limited settings. This study, conducted between February 2023 and May 2023, aimed to determine the optimal HbA1c cut-off for the diagnosis of diabetes mellitus by measuring HbA1c and fasting plasma glucose levels in 120 adults attending care at a tertiary hospital in Harare, Zimbabwe. The optimal HbA1c cut-off was 6.1% and glucose levels were strongly correlated with HbA1c values. The prevalence of diabetes mellitus was higher (28.3%) at our derived HbA1c cut-off than with the American Diabetes Association criterion (21.6%).\n\nWhat this study adds:\u00a0This study highlights the need for population-specific cut-off HbA1c values in the diagnosis of diabetes mellitus<\/jats:p>","DOI":"10.4102\/ajlm.v13i1.2373","type":"journal-article","created":{"date-parts":[[2024,4,23]],"date-time":"2024-04-23T07:41:46Z","timestamp":1713858106000},"update-policy":"https:\/\/doi.org\/10.4102\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Diagnostic cut-off value of haemoglobin A1c for diabetes mellitus in Harare, Zimbabwe"],"prefix":"10.4102","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8668-6458","authenticated-orcid":false,"given":"Chido W.","family":"Bvumbi","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04ze6rb18","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Zimbabwe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3531-7780","authenticated-orcid":false,"given":"Vinie","family":"Kouamou","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04ze6rb18","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Zimbabwe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9314-9792","authenticated-orcid":false,"given":"Ngalulawa","family":"Kone","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03rp50x72","id-type":"ROR","asserted-by":"publisher"}],"name":"University of the Witwatersrand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4363-7709","authenticated-orcid":false,"given":"Trust","family":"Zaranyika","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04ze6rb18","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Zimbabwe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5043-4486","authenticated-orcid":false,"given":"Lloyd","family":"Bowora","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04ze6rb18","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Zimbabwe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1760-4970","authenticated-orcid":false,"given":"Hilda T.","family":"Matarira","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04ze6rb18","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Zimbabwe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9711-3348","authenticated-orcid":false,"given":"Raylton P.","family":"Chikwati","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03rp50x72","id-type":"ROR","asserted-by":"publisher"}],"name":"University of the Witwatersrand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2580","published-online":{"date-parts":[[2024,4,23]]},"reference":[{"key":"ref0","doi-asserted-by":"crossref","unstructured":"Mutowo M, Gowda U, Chamunorwa J, Lorgelly P, Owen A, Renzaho A. 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