{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T18:41:27Z","timestamp":1785436887346,"version":"3.56.0"},"reference-count":21,"publisher":"AOSIS","issue":"1","license":[{"start":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T00:00:00Z","timestamp":1760400000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Background:\u00a0Glucose-6-phosphate dehydrogenase deficiency (G6PDD), a common inherited enzyme defect, associated with severe neonatal anaemia and hyperbilirubinaemia, can result in permanent neurologic damage or death. Prevalence of G6PDD-induced anaemia in vulnerable groups, like children, is not known in our setting.\nObjective:\u00a0This study was aimed at determining the prevalence of erythrocyte G6PDD-induced anaemia among children aged 0\u20135 years old seen at Jos University Teaching Hospital, North-Central Nigeria.\nMethods:\u00a0This was a hospital-based cross-sectional study conducted from February to June 2023. Glucose-6-phosphate dehydrogenase and haemoglobin levels were analysed colourimetrically. Data were analysed;\u00a0p\u00a0&lt; 0.05 was considered significant.\nResults:\u00a0Out of 100 children aged 0\u20135 years (54 male, 46 female), 40 (40%) were G6PD deficient. Nineteen (35.2%) of the G6PD-deficient children were male and 21 (45.7%) were female. Fifty-one (51%) children were anaemic, 23 (57.5%) were G6PDD-induced; 85 (85%) of the parents had no knowledge of G6PD and its deficiency.\nConclusion:\u00a0This study showed a high prevalence of G6PDD-induced anaemia among children in Jos. This suggests that there may be a need for early routine G6PD screening in children for early detection and proper intervention in those with the deficiency.\nWhat this study adds:\u00a0This study has objectively established high prevalence of anaemia, G6PDD and G6PDD-induced anaemia in children aged 0\u20135 years in Jos, Nigeria, highlighting the importance of G6PD screening in children.<\/jats:p>","DOI":"10.4102\/ajlm.v14i1.2733","type":"journal-article","created":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T09:22:44Z","timestamp":1760347364000},"update-policy":"https:\/\/doi.org\/10.4102\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Erythrocyte glucose-6-phosphate dehydrogenase deficiency-induced anaemia in children in Jos, North-Central Nigeria"],"prefix":"10.4102","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-6375-3862","authenticated-orcid":false,"given":"Justine D.","family":"Niandat","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/009kx9832","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Jos"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0745-1060","authenticated-orcid":false,"given":"Caroline A.","family":"Okoli","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/009kx9832","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Jos"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2580","published-online":{"date-parts":[[2025,10,14]]},"reference":[{"key":"ref0","doi-asserted-by":"crossref","unstructured":"Muzaffar IH, Boundaqji KR, Khatib HA, et al. 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