{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T23:13:41Z","timestamp":1782947621309,"version":"3.54.5"},"reference-count":24,"publisher":"AOSIS","issue":"1","license":[{"start":{"date-parts":[[2018,3,26]],"date-time":"2018-03-26T00:00:00Z","timestamp":1522022400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Curationis"],"abstract":"<jats:p>Background:\u00a0Nurses, as front-line care providers in the South Africa\u2019s health care system, are called upon to deliver integrated interventions for tuberculosis and human immunodeficiency virus (TB and HIV) including nurse-initiated management of anti-retroviral therapy (NIMART) and anti-TB treatment. Adherence to treatment guidelines and factors associated with non-adherence to treatment guidelines among nurses remain under explored.Purpose:\u00a0To explore and describe barriers to treatment guidelines adherence among nurses initiating and managing anti-retroviral therapy and anti-TB treatment in KwaZulu-Natal and North West provinces.Design:\u00a0This study employed a qualitative exploratory descriptive design.Methods:\u00a0Four semi-structured focus group interviews were conducted during 2014 each consisting of four to eight NIMART trained nurses. Audiotaped interviews were transcribed verbatim and analysed using Atlas T.I. software.Findings:\u00a0During data analysis, two themes emerged: (1) NIMART trained nurses\u2019 distress about TB and HIV guidelines adherence that is inclusive of lack of agreement with guidelines, poor motivation to implement guidelines, poor clinical support and supervision, resistance to change, insufficient knowledge or lack of awareness and (2) exterior factors inhibiting nurses\u2019 adherence to treatment guidelines which incorporated organisational factors, guidelines-related factors and patient-related factors.Conclusion:\u00a0This qualitative study identified that nurses have substantial concerns over guideline adherence. If NIMART trained nurses\u2019 barriers inhibiting adherence to treatment guidelines cannot be remedied, patient outcomes may suffer and South Africa will struggle to meet the 90-90-90 targets.<\/jats:p>","DOI":"10.4102\/curationis.v41i1.1808","type":"journal-article","created":{"date-parts":[[2018,3,21]],"date-time":"2018-03-21T23:05:01Z","timestamp":1521673501000},"source":"Crossref","is-referenced-by-count":16,"title":["Barriers to tuberculosis and human immunodeficiency virus treatment guidelines adherence among nurses initiating and managing anti-retroviral therapy in KwaZulu-Natal and North West provinces"],"prefix":"10.4102","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1689-9308","authenticated-orcid":false,"given":"Lufuno","family":"Makhado","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2871-6839","authenticated-orcid":false,"given":"Mashudu","family":"Davhana-Maselesele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6896-0134","authenticated-orcid":false,"given":"Jason 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