{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T09:42:27Z","timestamp":1785404547428,"version":"3.56.0"},"reference-count":49,"publisher":"AOSIS","license":[{"start":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T00:00:00Z","timestamp":1784505600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Background: Chronic kidney disease (CKD) is an emerging public health concern in Eswatini, with increasing prevalence among individuals with hypertension and diabetes. In primary healthcare facilities, professional nurses are essential to the early detection and management of CKD, guided by clinical practice guidelines and standardised protocols for non-communicable diseases.\nAim: This study explored the experiences of nurses in implementing clinical practice guidelines for the detection and management of CKD in primary healthcare facilities in Eswatini.\nSetting: Nine selected primary healthcare facilities across Eswatini.\nMethods: A qualitative, descriptive, and contextual design was used. Semi-structured interviews were conducted with 25 professional nurses, using purposive sampling. Interviews were transcribed, and thematic analysis was conducted following Gibbs\u2019 six-step framework, with ATLAS.ti used to support data management and organisation.\nResults: Three key themes and 12 sub-themes emerged from the data analysed. The three themes were: (1) nurses\u2019 experience in implementing clinical practice guidelines, (2) training on the implementation process and the content of clinical practice guidelines, and (3) benefits of clinical practice guideline implementation.\nConclusion: Investing in nurse training in clinical practice and its implementation is essential to improving the detection and management of CKD in Eswatini\u2019s primary healthcare facilities.\nContribution: The study provides valuable insights into the experiences of primary healthcare nurses implementing clinical practice guidelines for the early detection and management of CKD, shedding light on the challenges faced and opportunities to improve implementation in resource-constrained settings.<\/jats:p>","DOI":"10.4102\/hsag.v31i0.3216","type":"journal-article","created":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T07:07:19Z","timestamp":1784272039000},"update-policy":"https:\/\/doi.org\/10.4102\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Nurses\u2019 experiences implementing clinical practice guidelines for detecting and managing chronic kidney disease in Eswatini\u2019s primary healthcare facilities: A qualitative study"],"prefix":"10.4102","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7042-3872","authenticated-orcid":false,"given":"Delisile F.","family":"Simelane","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05bk57929","id-type":"ROR","asserted-by":"publisher"}],"name":"Stellenbosch University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4134-3221","authenticated-orcid":false,"given":"Portia J.","family":"Jordan","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05bk57929","id-type":"ROR","asserted-by":"publisher"}],"name":"Stellenbosch University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2253-6354","authenticated-orcid":false,"given":"Wilma","family":"ten Ham-Baloyi","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03r1jm528","id-type":"ROR","asserted-by":"publisher"}],"name":"Nelson Mandela University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2580","published-online":{"date-parts":[[2026,7,20]]},"reference":[{"key":"ref0","doi-asserted-by":"crossref","unstructured":"Abimbola, S., Baatiema, L., Bigdeli, M. & Yadav, P., 2020, \u2018The challenges of implementing health system guidance in low- and middle-income countries: A systematic review\u2019, Health Policy and Planning 35(2), 147\u2013162. https:\/\/doi.org\/10.1093\/heapol\/czz055","DOI":"10.1093\/heapol\/czz055"},{"key":"ref1","unstructured":"Bello, A.K., Levin, A. & Tonelli, M., 2019a, \u2018Global kidney health atlas: A report by the International Society of Nephrology on the global burden of kidney disease and its risk factors\u2019, Kidney International Supplements 9(2), 31\u201372. https:\/\/doi.org\/10.1016\/j.kisu.2019.05.015"},{"key":"ref2","unstructured":"Bello, A.K., Levin, A., Tonelli, M., Okpechi, I.G., Feehally, J. & Harris, D.C.H., 2019b, \u2018Global kidney health atlas: A report by the International Society of Nephrology\u2019, Kidney International Supplements 9(1), 1\u201374. https:\/\/doi.org\/10.1016\/j.kisu.2019.01.001"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Brouwers, M.C., Kho, M.E., Browman, G.P., Burgers, J.S., Cluzeau, F., Feder, G. et al., 2019, \u2018AGREE II: Advancing guideline development, reporting, and evaluation in healthcare\u2019, CMAJ 182(18), E839\u2013E842. https:\/\/doi.org\/10.1503\/cmaj.090449","DOI":"10.1503\/cmaj.090449"},{"key":"ref4","unstructured":"Camargo, F.C., Iwamoto, H.H., Andrade, A.C., Fernandes, M.F.P. & Miranzi, S.D.A., 2022, \u2018Impact of evidence-based practice on health care quality: A literature review\u2019, Revista Brasileira de Enfermagem 75(3), e20210324. https:\/\/doi.org\/10.1590\/0034-7167-2021-0324"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Chansa, C., Chitah, B.M. & Kachimba, J.S., 2022, \u2018Access to clinical practice guidelines in primary health centres in Zambia: Challenges and opportunities\u2019, African Health Sciences 22(1), 234\u2013243. https:\/\/doi.org\/10.4314\/ahs.v22i1.29","DOI":"10.4314\/ahs.v22i1.29"},{"key":"ref6","unstructured":"George, J.A., Brandenburg, J.T., Fabian, J., Crowther, N.J. & Kengne, A.P., 2022, \u2018Chronic kidney disease in sub-Saharan Africa: Epidemiology, risk factors and prevention\u2019, Nature Reviews Nephrology 18(4), 1\u201315. https:\/\/doi.org\/10.1038\/s41581-021-00520-9"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Gibbs, G.R., 2007, \u2018Thematic coding and categorizing\u2019, in G.R. 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