{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T15:42:51Z","timestamp":1785426171625,"version":"3.56.0"},"reference-count":11,"publisher":"AOSIS","issue":"1","license":[{"start":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T00:00:00Z","timestamp":1739404800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Background:\u00a0Oesophageal high-resolution manometry (HRM) is commonly used in the evaluation of patients presenting with upper gastrointestinal tract symptoms where primary oesophageal motility disorders are suspected. At our hospital, one doctor can perform and interpret HRM, with the hospital serving a population of approximately 3 million people. There is a paucity of data on HRM findings in South Africa.\n\nMethods:\u00a0This study included data from patients that underwent HRM between January 2018 and January 2023, using the hospitals electronic note-keeping system to access records. High-resolution manometry was performed for all patients using a water state catheter with 24 pressure channels. The Chicago classification version 3 was used for reporting.\n\nResults:\u00a0A total of 210 patients were included in this study. The average age of patients included was 50 years (standard deviation [s.d.] \u00b1 15.2) old with a female predominance (n\u00a0= 149, 71.0%). Indications included gastroesophageal reflux disease (GORD) (65.7%), refractory heartburn (62.4%), dysphagia (37.6%), non-cardiac chest pain (16.7%), pre-procedurally (5.7%) and post-procedurally (14.8%). Many primary oesophageal motility disorders were observed, including ineffective oesophageal motility (20%), achalasia (11.4%), absent contractility (4.3%), oesophagogastric junction outflow obstruction (1.9%) and jackhammer oesophagus (1%). Normal findings accounted for 61%. The most common type of achalasia was type 1 (n\u00a0= 16, 66%).\n\nConclusion:\u00a0This study, being the first of its kind in South Africa, highlights the role of HRM in the diagnosis of primary oesophageal motility disorders with ineffective oesophageal motility being the most common pathology and GORD being the most common indication for HRM. Achalasia type 1 was the common type diagnosed.\n\nContribution:\u00a0HRM, despite its scarce availability, remains an important diagnostic tool in evaluating gastrointestinal pathologies.<\/jats:p>","DOI":"10.4102\/jcmsa.v3i1.113","type":"journal-article","created":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T18:43:21Z","timestamp":1739472201000},"update-policy":"https:\/\/doi.org\/10.4102\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["The role of high-resolution manometry in a resource challenged service"],"prefix":"10.4102","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5742-8903","authenticated-orcid":false,"given":"Mohammed A.","family":"Parker","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05bk57929","id-type":"ROR","asserted-by":"publisher"}],"name":"Stellenbosch University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1479-9948","authenticated-orcid":false,"given":"Mogamad S.","family":"Gabriel","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05bk57929","id-type":"ROR","asserted-by":"publisher"}],"name":"Stellenbosch University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0274-6909","authenticated-orcid":false,"given":"Muhammed S.","family":"Moolla","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05bk57929","id-type":"ROR","asserted-by":"publisher"}],"name":"Stellenbosch University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3039-5918","authenticated-orcid":false,"given":"Christoffel J.","family":"van Rensburg","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05bk57929","id-type":"ROR","asserted-by":"publisher"}],"name":"Stellenbosch University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6703-5822","authenticated-orcid":false,"given":"Desiree L.","family":"Moodley","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05bk57929","id-type":"ROR","asserted-by":"publisher"}],"name":"Stellenbosch University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2824-0646","authenticated-orcid":false,"given":"Wesley P.","family":"du Plessis","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05bk57929","id-type":"ROR","asserted-by":"publisher"}],"name":"Stellenbosch University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-5823-556X","authenticated-orcid":false,"given":"Ahmad A.","family":"Abdelsalem","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05bk57929","id-type":"ROR","asserted-by":"publisher"}],"name":"Stellenbosch University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2580","published-online":{"date-parts":[[2025,2,13]]},"reference":[{"key":"ref0","doi-asserted-by":"crossref","unstructured":"Van Hoeij FB, Bredenoord AJ. Clinical application of esophageal high-resolution manometry in the diagnosis of esophageal motility disorders. J Neurogastroenterol Motil. 2016;22(1):6\u201313. https:\/\/doi.org\/10.5056\/jnm15177","DOI":"10.5056\/jnm15177"},{"key":"ref1","unstructured":"Carlson DA, Pandolfino JE. High-resolution manometry in clinical practice. Gastroenterol Hepatol. 2015;11(6):374\u2013384."},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Kahrilas PJ, Bredenoord AJ, Fox M, et al. The Chicago Classification of esophageal motility disorders, v3.0. Neurogastroenterol Motil. 2015;27(2):160\u2013174. https:\/\/doi.org\/10.1111\/nmo.12477","DOI":"10.1111\/nmo.12477"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Kahrilas PJ, Ghosh SK, Pandolfino JE. Esophageal motility disorders in terms of pressure topography: The Chicago classification. J Clin Gastroenterol. 2008;42(5):627\u2013635. https:\/\/doi.org\/10.1097\/MCG.0b013e31815ea291","DOI":"10.1097\/MCG.0b013e31815ea291"},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"Yadlapati R, Kahrilas PJ, Fox MR, et al. Esophageal motility disorders on high-resolution manometry: Chicago classification version 4.0\u00a9. Neurogastroenterol Motil. 2021;33(1):e14058. https:\/\/doi.org\/10.1111\/nmo.14053","DOI":"10.1111\/nmo.14053"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Fox MR, Pandolfino JE, Sweis R, et al. Inter-observer agreement for diagnostic classification of esophageal motility disorders defined in high-resolution manometry. Dis Esophagus. 2015;28(8):711\u2013719. https:\/\/doi.org\/10.1111\/dote.12278","DOI":"10.1111\/dote.12278"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Soudagar AS, Sayuk GS, Gyawali CP. Learners favour high resolution oesophageal manometry with better diagnostic accuracy over conventional line tracings. Gut. 2012;61(6):798\u2013803. https:\/\/doi.org\/10.1136\/gutjnl-2011-301145","DOI":"10.1136\/gutjnl-2011-301145"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Naguib GG, Hassan M, Elshafie AI, Naguib MG. Esophageal motility abnormalities in Egyptian patients using high resolution esophageal manometry: A descriptive study. Egypt J Intern Med. 2022;34(1):2. https:\/\/doi.org\/10.1186\/s43162-021-00097-2","DOI":"10.1186\/s43162-021-00097-2"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Rehman H, Abid A, Awan S, Hashmi FL, Abid S. Spectrum and clinical outcome of motility disorders on high-resolution esophageal manometry: A study from a tertiary center on patients with dysphagia in Pakistan. Cureus. 2020;12(12):e12088. https:\/\/doi.org\/10.7759\/cureus.12088","DOI":"10.7759\/cureus.12088"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Aziz Q, Fass R, Gyawali CP, Miwa H, Pandolfino JE, Zerbib F. Functional oesophageal disorders. 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Neurogastroenterol Motil. 2019;31(9):e13584. https:\/\/doi.org\/10.1111\/nmo.13584","DOI":"10.1111\/nmo.13584"}],"container-title":["Journal of the Colleges of Medicine of South Africa"],"original-title":[],"link":[{"URL":"https:\/\/jcmsa.org.za\/index.php\/jcmsa\/article\/viewFile\/113\/420","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jcmsa.org.za\/index.php\/jcmsa\/article\/viewFile\/113\/421","content-type":"application\/epub+zip","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jcmsa.org.za\/index.php\/jcmsa\/article\/viewFile\/113\/422","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jcmsa.org.za\/index.php\/jcmsa\/article\/viewFile\/113\/423","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jcmsa.org.za\/index.php\/jcmsa\/article\/view\/113\/423","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T09:33:06Z","timestamp":1757928786000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcmsa.org.za\/index.php\/jcmsa\/article\/view\/113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,13]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,1,1]]}},"URL":"https:\/\/doi.org\/10.4102\/jcmsa.v3i1.113","relation":{},"ISSN":["3105-4331","2960-110X"],"issn-type":[{"value":"3105-4331","type":"print"},{"value":"2960-110X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,13]]},"article-number":"a113"}}