{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T15:09:26Z","timestamp":1785424166202,"version":"3.56.0"},"reference-count":39,"publisher":"AOSIS","issue":"2","license":[{"start":{"date-parts":[[2025,2,23]],"date-time":"2025-02-23T00:00:00Z","timestamp":1740268800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Background:\u00a0Post-exposure severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing following health facility outbreaks may control the spread of infection.\n\nAim:\u00a0This study aimed to assess the impact of testing for SARS-CoV-2 infection on health outcomes during healthcare facility outbreaks.\n\nSetting:\u00a0This review included studies conducted at skilled nursing facilities, a cancer centre, and a geriatric psychiatric facility.\n\nMethods:\u00a0We followed the methods for conducting rapid systematic reviews, searched databases from December 2019 to August 2022, assessed the risk of bias using the modified Newcastle Ottawa scale, and graded the certainty of evidence using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. We pooled the prevalence, mortality, and hospitalisation results as appropriate.\n\nResults:\u00a0Of the 3055 articles from database search, no study was eligible for inclusion as outlined in the protocol. However, eight non-comparative reports (case series) in skilled nursing facilities were included. The pooled prevalence of SARS-CoV-2 infection among residents of care homes and patients were 38% (95% confidence interval [CI] = 25% \u2013 51%; 5 studies, 2044 participants;\u00a0I2\u00a0= 94%, very low certainty evidence) and was 12% (95% CI = 6% \u2013 19%; 5 studies, 2312 participants;\u00a0I2\u00a0= 94%, very low certainty evidence) for exposed healthcare workers. The pooled mortality estimate and hospitalisation rate were 17% and 24%, respectively, (very low certainty evidence).\n\nConclusion:\u00a0There is no identified evidence for or against testing of people in healthcare facilities where there is ongoing transmission of SARS-CoV-2 infection.\n\nContribution:\u00a0The evaluation of the effectiveness of testing strategies during SARS-CoV-2 outbreaks need baseline and follow-up data from well-designed before and after studies appropriate for the setting.<\/jats:p>","DOI":"10.4102\/jphia.v16i2.623","type":"journal-article","created":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T09:55:01Z","timestamp":1741859701000},"update-policy":"https:\/\/doi.org\/10.4102\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Post-exposure testing at healthcare facilities with SARS-CoV-2 transmission: A rapid review"],"prefix":"10.4102","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5654-2963","authenticated-orcid":false,"given":"Emmanuel E.","family":"Effa","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05qderh61","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Calabar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1149-3130","authenticated-orcid":false,"given":"Okokon","family":"Ita","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05qderh61","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Calabar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1703-6670","authenticated-orcid":false,"given":"Joshua","family":"Mwankon","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05qderh61","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Calabar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-3277-7834","authenticated-orcid":false,"given":"Funmi","family":"Siyanbade","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05qderh61","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Calabar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3154-5956","authenticated-orcid":false,"given":"Francis","family":"Iwomi","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05qderh61","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Calabar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7951-3030","authenticated-orcid":false,"given":"Eleanor","family":"Ochodo","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04r1cxt79","id-type":"ROR","asserted-by":"publisher"}],"name":"Kenya Medical Research Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1306-1721","authenticated-orcid":false,"given":"Gemma","family":"Villanueva","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00dbkrq51","id-type":"ROR","asserted-by":"publisher"}],"name":"Cochrane"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6144-9413","authenticated-orcid":false,"given":"Martin M.","family":"Meremikwu","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05qderh61","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Calabar"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2580","published-online":{"date-parts":[[2025,2,23]]},"reference":[{"key":"ref0","unstructured":"WHO. 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