{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T09:46:10Z","timestamp":1791107170434,"version":"4.1.0"},"reference-count":0,"publisher":"AOSIS","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Onderstepoort J Vet Res"],"abstract":"<jats:p>The protective efficacy of isometamidium chloride  (ISMM) and diminazene aceturate (DIM) against Trypanosoma brucei, Trypanosoma  congolense and Trypanosoma vivax infections in cattle under a  suppressed tsetse population was assessed in southeast Uganda. A total of 66 and  57 trypanosome-infected cattle were treated with ISMM and DIM, respectively  together with 177 trypanosomefree animals not treated were followed for 12  months, checked every 4 weeks. There was no statistical difference in the mean  time to infection with any trypanosome species in animals treated with ISMM or  DIM. However, the mean time to trypanosome infection was significantly longer  for treated animals than controls. The mean time to infection with each of the  three trypanosome species differed significantly, with the average time to T.  vivax infection the lowest, followed by T. congolense and then T.  brucei. The protective efficacy of DIM was as good as that of ISMM; implying  curative treatments against trypanosomosis are sufficient for combination with  tsetse control. Isometamidium chloride or DIM had the highest impact on T.  brucei and T. congolense infections in cattle.<\/jats:p>","DOI":"10.4102\/ojvr.v71i3.265","type":"journal-article","created":{"date-parts":[[2012,8,27]],"date-time":"2012-08-27T03:22:23Z","timestamp":1346037743000},"source":"Crossref","is-referenced-by-count":8,"title":["Protective efficacy of isometamidium chloride and diminazene aceturate against natural &lt;i&gt;Trypanosoma brucei&lt;i\/&gt;, &lt;i&gt;Trypanosoma congolense&lt;i\/&gt; and &lt;i&gt;Trypanosoma vivax&lt;i\/&gt; infections in cattle under a suppressed tsetse population in Uganda"],"prefix":"10.4102","volume":"71","author":[{"given":"J.W.","family":"Magona","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.S.P.","family":"Mayende","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Okiria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.M.","family":"Okuna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2580","published-online":{"date-parts":[[2004,11,8]]},"container-title":["Onderstepoort J Vet Res"],"original-title":[],"link":[{"URL":"http:\/\/ojvr.org\/index.php\/ojvr\/article\/viewFile\/265\/245","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T07:21:51Z","timestamp":1496301711000},"score":1,"resource":{"primary":{"URL":"http:\/\/ojvr.org\/index.php\/ojvr\/article\/view\/265"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,11,8]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2004,11,8]]}},"URL":"https:\/\/doi.org\/10.4102\/ojvr.v71i3.265","relation":{},"ISSN":["2219-0635","0030-2465"],"issn-type":[{"value":"2219-0635","type":"electronic"},{"value":"0030-2465","type":"print"}],"subject":[],"published":{"date-parts":[[2004,11,8]]}}}