{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T23:42:07Z","timestamp":1648942927470},"reference-count":0,"publisher":"AOSIS","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Onderstepoort J Vet Res"],"abstract":"<jats:p>A wild strain of Eimeria tenella was  isolated and utilized for immunization studies. Its optimal sporulation  was attained at room temperature 24-25 \u00b0C after 24-48 h. Two groups of  chicks were immunized  by dosing a graded dose of five oocysts\/chick\/day for 6 days followed by  50 oocysts\/chick\/day  for 7 days. A third group was not immunized and served as a negative  control. Immunized chicks  gained mass at the same rate as unimmunized ones, but when challenged  with 200 000  oocysts\/chick, mass gains declined in the unimmunized group. The growth  rate of immunized chicks  was not affected by challenge (P &gt; 0.05). Upon challenge, unimmunized  chicks produced significantly  more oocysts than immunized chicks (P &lt; 0.005). Immunized chicks  withstood a challenged  with 200 000 oocysts\/chick without developing any clinical signs whereas  the unimmunized chicks  developed typical clinical signs of coccidiosis. Unimmunized chicks had  significantly more severe  lesions in the caecum than any other group (P &gt; 0.005) and also  produced significantly more oocysts  than any other group (P &gt; 0.005).<\/jats:p>","DOI":"10.4102\/ojvr.v72i3.203","type":"journal-article","created":{"date-parts":[[2012,8,27]],"date-time":"2012-08-27T03:22:23Z","timestamp":1346037743000},"source":"Crossref","is-referenced-by-count":0,"title":["Immunization of young chicks using graded dose of wild strain of &lt;i&gt;Eimeria tenella&lt;\/i&gt;"],"prefix":"10.4102","volume":"72","author":[{"given":"E.N.","family":"Kimbita","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.M.","family":"Samani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.N.","family":"Machange","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.S.","family":"Silayo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2580","published-online":{"date-parts":[[2005,9,15]]},"container-title":["Onderstepoort J Vet Res"],"original-title":[],"link":[{"URL":"http:\/\/ojvr.org\/index.php\/ojvr\/article\/viewFile\/203\/193","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T07:21:29Z","timestamp":1496301689000},"score":1,"resource":{"primary":{"URL":"http:\/\/ojvr.org\/index.php\/ojvr\/article\/view\/203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,9,15]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2005,9,15]]}},"URL":"https:\/\/doi.org\/10.4102\/ojvr.v72i3.203","relation":{},"ISSN":["2219-0635","0030-2465"],"issn-type":[{"value":"2219-0635","type":"electronic"},{"value":"0030-2465","type":"print"}],"subject":[],"published":{"date-parts":[[2005,9,15]]}}}