{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T17:24:54Z","timestamp":1649179494885},"reference-count":0,"publisher":"AOSIS","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Onderstepoort J Vet Res"],"abstract":"<jats:p>The first detailed description of the pathology of  tuberculosis, caused by Mycobacterium tuberculosis, in springbok is  reported. The springbok were part of a semi-free-ranging herd kept on the  grounds of iThemba Laboratory for Accelerator Based Science (LABS) in the Kuils  River district of the Western Cape Province, South Africa. Mycobacterium  tuberculosis was isolated from three animals out of a total of 33 sampled,  with two animals showing tuberculosis lesions. The index case was an adult ewe  that showed advanced miliary tuberculosis with marked macroscopic and  microscopic lesions in the lungs, pleura and respiratory lymph nodes, and  numerous acid-fast bacilli. Six healthy rams were sampled nine months later and  a pilot study indicated miliary tuberculosis lesions in one ram, which again  were macroscopically most prominent in the lungs, pleura and respiratory lymph  nodes. Macroscopic lesions were also noted in the sternal, iliac, prefemoral and  retropharyngeal lymph nodes. Microscopy in this animal revealed lesions in the  macroscopically affected organs as well as numerous other lymph nodes, and  suspected lesions occurred in the testicle and colon. Acid-fast bacilli were  scarce to moderate in affected organs. Because of the miliary nature of the  lesions in both affected animals, the route of infection could not be  established conclusively. The lesions in most affected organs of both animals  resembled classical tuberculous granulomas. A main study conducted on healthy  animals 19 months after the pilot study failed to find any animal with  tuberculosis lesions in the group of 25 sampled, and all were negative for  mycobacteria via mycobacterial culture.<\/jats:p>","DOI":"10.4102\/ojvr.v76i4.26","type":"journal-article","created":{"date-parts":[[2012,8,27]],"date-time":"2012-08-27T07:21:52Z","timestamp":1346052112000},"source":"Crossref","is-referenced-by-count":1,"title":["The pathology of tuberculosis caused by Mycobacterium tuberculosis in a herd of semi-free-ranging springbok (&lt;i&gt;Antidorcas marsupialis&lt;\/i&gt;)"],"prefix":"10.4102","volume":"76","author":[{"given":"T.A.","family":"Gouws","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.C.","family":"Williams","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2580","published-online":{"date-parts":[[2009,9,9]]},"container-title":["Onderstepoort J Vet Res"],"original-title":[],"link":[{"URL":"http:\/\/ojvr.org\/index.php\/ojvr\/article\/viewFile\/26\/23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T11:20:07Z","timestamp":1496316007000},"score":1,"resource":{"primary":{"URL":"http:\/\/ojvr.org\/index.php\/ojvr\/article\/view\/26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9,9]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2009,9,9]]}},"URL":"https:\/\/doi.org\/10.4102\/ojvr.v76i4.26","relation":{},"ISSN":["2219-0635","0030-2465"],"issn-type":[{"value":"2219-0635","type":"electronic"},{"value":"0030-2465","type":"print"}],"subject":[],"published":{"date-parts":[[2009,9,9]]}}}