{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:28:45Z","timestamp":1787030925220,"version":"build-2736575974"},"reference-count":41,"publisher":"AOSIS","issue":"1","license":[{"start":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T00:00:00Z","timestamp":1680566400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Onderstepoort j. vet. res."],"abstract":"<jats:p>Infection with\u00a0Coxiella burnetii\u00a0causes significant economic impact and poses zoonotic risk to people exposed to livestock, yet few studies in South Africa have assessed seroprevalence of\u00a0C. burnetii\u00a0infection and no information is available for goats. Very little information is available regarding risk factors and outcomes of\u00a0C. burnetii\u00a0infection in peri-urban farming areas where widespread mixing of ruminants occurs. This study estimated the seroprevalence of\u00a0C. burnetii\u00a0infection among communally farmed goats in an area adjacent to the densely populated Gauteng province. Sera were collected from 216 goats in 39 herds, and questionnaires were completed to establish management practices as potential risk factors.\u00a0C. burnetii\u00a0antibody testing was done by ELISA. Thirty two out of 216 goats tested positive for\u00a0C. burnetii\u00a0antibodies and the overall seroprevalence, adjusted for sampling weights and clustering, was 18.4% (95% confidence interval [CI]: 12.2% \u2013 23.5%). The intraclass correlation coefficient was 0.06, indicating low-to-moderate clustering. Multiple logistic regression showed age was significantly associated with seropositivity, with higher seroprevalence in animals \u2265 19 months old (26%) than animals \u2264 6 months old (6%) (odds ratio [OR]: 6.6;\u00a0p\u00a0= 0.010). We concluded\u00a0C. burnetii\u00a0infection is common in goats in Moretele and a potential cause of abortion in goats and poses the potential zoonotic disease risk.Contribution:\u00a0Despite the threats posed on animal health and productivity, scant information is published on\u00a0C. burnetii\u00a0in South Africa. This research established preliminary estimates of\u00a0C. burnetii\u00a0seroprevalence. The research is original from a South African perspective, relevant to Africa and focused on infectious disease in livestock.<\/jats:p>","DOI":"10.4102\/ojvr.v90i1.2071","type":"journal-article","created":{"date-parts":[[2023,4,8]],"date-time":"2023-04-08T07:57:11Z","timestamp":1680940631000},"source":"Crossref","is-referenced-by-count":10,"title":["Seroprevalence and factors associated with Coxiella burnetii exposure in goats in Moretele"],"prefix":"10.4102","volume":"90","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8076-426X","authenticated-orcid":false,"given":"Rungano","family":"Magadu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2268-9748","authenticated-orcid":false,"given":"Peter N.","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2580","published-online":{"date-parts":[[2023,4,4]]},"reference":[{"key":"ref0","unstructured":"Accuweather, 2022, Accuweather, viewed 15 February 2022, from https:\/\/www.accuweather.com\/en\/za\/makapanstad\/299847\/daily-weather-forecast\/299847?day=2."},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"Adesiyun, A.A., Knobel, D.L., Thompson, P.N., Wentzel, J., Kolo, F.B., Kolo, A.O. et al., 2020, 'Sero-epidemiological study of selected zoonotic and abortifacient pathogens in cattle at a Wildlife-Livestock Interface in South Africa. 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