{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T03:39:13Z","timestamp":1777952353228,"version":"3.51.4"},"reference-count":21,"publisher":"AOSIS","issue":"1","license":[{"start":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:00:00Z","timestamp":1777507200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:00:00Z","timestamp":1777507200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Onderstepoort j. vet. res."],"abstract":"<jats:p>Cysticercosis is a neglected zoonotic disease caused by the larval stages of\u00a0Taenia asiatica, T. saginata\u00a0and\u00a0T. solium. Its prevalence varies across regions, with limited data available in South Africa, particularly in Mpumalanga province. This study aimed to determine the seroprevalence and distribution of bovine and porcine cysticercosis in rural communities of Mpumalanga province, South Africa. A cross-sectional survey was conducted from 2021 to 2022 in Ehlanzeni and Nkangala districts. Blood samples were collected from 384 cattle and 336 pigs and analysed using the Apdia\u00ae\u00a0cysticercosis AgELISA kit. Logistic regression was used to estimate odds of infection, with statistical significance set at\u00a0p\u00a0 0.05. Overall seroprevalence of bovine cysticercosis was 35.2% (95% confidence interval [CI]: 30.5\u201340.2), while porcine cysticercosis was 4.8% (95% CI: 2.8\u20137.6). Seroprevalence varied across districts and municipalities in Mpumalanga province, with evidence of spatial heterogeneity in both cattle and pigs. The higher prevalence in cattle is likely because of free-range grazing practices, increasing exposure to Taenia-contaminated environments. Pigs, mostly penned, had lower infection rates.Contribution:\u00a0This study provides the first baseline data on bovine and porcine cysticercosis in Mpumalanga province, highlighting the need for improved livestock management, sanitation, farmer education and targeted surveillance to reduce transmission.<\/jats:p>","DOI":"10.4102\/ojvr.v93i1.2261","type":"journal-article","created":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T06:10:25Z","timestamp":1777443025000},"update-policy":"https:\/\/doi.org\/10.4102\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Seroprevalence and distribution of bovine and porcine cysticercosis in rural areas of Mpumalanga province, South Africa"],"prefix":"10.4102","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-0169-7884","authenticated-orcid":false,"given":"Usman A.","family":"Ahmed","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8651-0014","authenticated-orcid":false,"given":"Malitaba A.","family":"Mlangeni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7398-1741","authenticated-orcid":false,"given":"Ana M.","family":"Tsotetsi-Khambule","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2580","published-online":{"date-parts":[[2026,4,30]]},"reference":[{"key":"ref0","doi-asserted-by":"crossref","unstructured":"Assana, E., Lightowlers, M., Zoli, A.P. 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slaughtered at low-throughput abattoirs in South Africa\u2019, Onderstepoort Journal of Veterinary Research 91(1), a2157. https:\/\/doi.org\/10.4102\/OJVR.v91i1.2157","DOI":"10.4102\/OJVR.v91i1.2157"},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"Eichenberger, R.M., Lewis, F., Gabriel, S. & Dorny, P., 2013, \u2018Multi-test analysis and model-based estimation of the prevalence of Taenia saginata cysticercus infection in naturally infected dairy cows in the absence of a \u201cgold standard\u201d reference test\u2019, International Journal for Parasitology 43(10), 853\u2013859. https:\/\/doi.org\/10.1016\/j.ijpara.2013.05.011","DOI":"10.1016\/j.ijpara.2013.05.011"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Harrison, L.J.S., Joshua, G.W., Wright, S.H. & Parkhouse, R.M.E., 1989, \u2018Specific detection of circulating surface\/secreted glycoproteins of viable cysticerci in Taenia saginata cysticercosis\u2019, Parasite Immunology 11, 351\u2013370. https:\/\/doi.org\/10.1111\/j.1365-3024.1989.tb00673.x","DOI":"10.1111\/j.1365-3024.1989.tb00673.x"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Joshi, D.D., Maharjan, M., Johansen, M.V., Willingham, A.L. & Sharma, M., 2019, \u2018Improving meat inspection and control in resource-poor communities: The Nepal example\u2019, Acta Tropica 87(1), 119\u2013127. https:\/\/doi.org\/10.1016\/S0001-706X(03)00028-7","DOI":"10.1016\/S0001-706X(03)00028-7"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Krecek, R.C., Mohammed, H., Michael, L.M., Schantz, P.M., Ntanjana, L., Morey, L. et al., 2008, \u2018Risk factors of porcine cysticercosis in the Eastern Cape Province, South Africa\u2019, PLoS One 3(7), e37718. https:\/\/doi.org\/10.1371\/journal.pone.0037718","DOI":"10.1371\/journal.pone.0037718"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Laranjo-Gonz\u00e1lez, M., Devleesschauwer, B., Trevisan, C., Allepuz, A., Sotiraki, S., \u0160ark\u016bnas, M. et 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Kassuku, A.A., Carabin, H., Mlozi, M.R.S., Mlangwa, J.E.D. & Willingham, A.L., 2019, \u2018Spatial clustering of porcine cysticercosis in Mbulu district, northern Tanzania\u2019, PLoS Neglected Tropical Diseases 13(5), e0007426. https:\/\/doi.org\/10.1371\/journal.pntd.0007426","DOI":"10.1371\/journal.pntd.0007426"},{"key":"ref12","unstructured":"Nkosi, D.V., Bekker, J.L. & Hoffman, L.C., 2019, \u2018Impact of communal bovine farming practices on meat safety in Central Bushbuckridge, South Africa\u2019, International Journal of Veterinary Science 8(4), 300\u2013308."},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"Nkouawa, A., Dschanou, A.R., Moyou-Somo, R., Sako, Y. & Ito, A., 2017, \u2018Seroprevalence and risk factors of human cysticercosis and taeniasis in a highly endemic area of epilepsy in Bangoua, West Cameroon\u2019, Acta Tropica 165, 116\u2013120. 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Harrison, L.J.S., 2017, \u2018Sero-prevalence of Taenia spp. infections in cattle and pigs in rural farming communities in Free State and Gauteng provinces, South Africa\u2019, Acta Tropica 172, 91\u201396. https:\/\/doi.org\/10.1016\/j.actatropica.2017.04.019","DOI":"10.1016\/j.actatropica.2017.04.019"},{"key":"ref19","doi-asserted-by":"crossref","unstructured":"Veary, C.M. & Manoto, S.N., 2008, \u2018Neurocysticercosis: A possible cause of epileptiform seizures in villages served by Bethanie clinic in the North West Province\u2019, Journal of the South African Veterinary Association 79, 84\u201388. https:\/\/doi.org\/10.4102\/jsava.v79i2.249","DOI":"10.4102\/jsava.v79i2.249"},{"key":"ref20","unstructured":"World Health Organization (WHO) and Food and Agriculture Organization (FAO), 2005, \u2018Guidelines for surveillance, prevention and control of taeniasis\/cysticercosis\u2019, in M.A. Gemmell, Z. Matyas, Z.S. Pawlowski & E.J.L. 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