{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T02:15:27Z","timestamp":1792894527803,"version":"4.5.0"},"reference-count":22,"publisher":"AOSIS","issue":"1","license":[{"start":{"date-parts":[[2020,6,17]],"date-time":"2020-06-17T00:00:00Z","timestamp":1592352000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Afr. j. prim. health care fam. med."],"abstract":"<jats:p>Background: Malaria diagnosis using microscopy is currently the gold standard. However, malaria rapid diagnostic tests (mRDTs) were developed to simplify the diagnosis in regions without access to functional microscopy.Aim: The objective of this study was to compare the diagnostic accuracy of mRDT CareStatTM with microscopy.Setting: This study was conducted in the paediatric primary care clinic of the Federal Medical Centre, Asaba, Nigeria.Methods: A cross-sectional study for diagnostic accuracy was conducted from May 2016 to October 2016. Ninety-eight participants were involved to obtain a precision of 5%, sensitivity of mRDT CareStatTM of 95% from published work and 95% level of confidence after adjusting for 20% non-response rate or missing data. Consecutive participants were tested using both microscopy and mRDT. The results were analysed using EPI Info Version 7.Results: A total of 98 children aged 3\u201359 months were enrolled. Malaria prevalence was found to be 53% (95% confidence interval [CI] = 46% \u2013 60%), whilst sensitivity and specificity were 29% (95% CI = 20% \u2013 38%) and 89% (95% CI = 83% \u2013 95%), respectively. The positive and negative predictive values were 75% (95% CI = 66.4% \u2013 83.6%) and 53% (95% CI = 46% \u2013 60%), respectively.Conclusion: Agreement between malaria parasitaemia using microscopy and mRDT positivity increased with increase in the parasite density. The mRDT might be negative when malaria parasite density using microscopy is low.<\/jats:p>","DOI":"10.4102\/phcfm.v12i1.2212","type":"journal-article","created":{"date-parts":[[2020,5,5]],"date-time":"2020-05-05T10:58:31Z","timestamp":1588676311000},"source":"Crossref","is-referenced-by-count":23,"title":["Sensitivity and specificity of malaria rapid diagnostic test (mRDT CareStatTM) compared with microscopy amongst under five children attending a primary care clinic in southern Nigeria"],"prefix":"10.4102","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6757-4223","authenticated-orcid":false,"given":"Oluwagbenga","family":"Ogunfowokan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2616-3214","authenticated-orcid":false,"given":"Bamidele A.","family":"Ogunfowokan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2280-7732","authenticated-orcid":false,"given":"Anthony I.","family":"Nwajei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2580","published-online":{"date-parts":[[2020,6,17]]},"reference":[{"key":"ref0001","first-page":"858427","volume":"2010","author":"Portero","year":"2010","journal-title":"Malar Res Treat"},{"issue":"1","key":"ref0002","first-page":"2006","volume":"12","author":"Harriet Pasquale","year":"2013","journal-title":"Malar J"},{"key":"ref0003","doi-asserted-by":"publisher","DOI":"10.1016\/j.parint.2007.03.001"},{"key":"ref0004","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-13-101"},{"key":"ref0005","doi-asserted-by":"publisher","DOI":"10.3923\/jp.2015.120.126"},{"key":"ref0007","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw628"},{"key":"ref0008","first-page":"1","author":"World Health Organization","year":"2014","journal-title":"World Malaria Report 2014; 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