{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T13:09:26Z","timestamp":1787663366254,"version":"build-2736575974"},"reference-count":32,"publisher":"AOSIS","issue":"1","license":[{"start":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T00:00:00Z","timestamp":1729468800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Tuberculosis (TB) treatment success rates (TSR) remain low in Lesotho. The country achieved TSR of 76% in 2020, which is far below the World Health Organization\u2019s 95% target set for 2030. This study determined the level of treatment success and factors associated with unfavourable treatment outcomes. This descriptive cross-sectional study used patient records to perform descriptive and logistic regression analyses. Sixty-one per cent of the 336 TB patients were male. Two hundred and eighty-nine had favourable outcomes, of which 10% died in the course of treatment. Patients \u2264 44 years old, and those with supported treatment, had lower odds of unfavourable treatment outcomes, respectively, adjusted odds ration [aOR] = 0.39 (95% CI: 0.19\u20130.78) and aOR = 0.22 (95% CI: 0.08\u20130.62),\u00a0p\u00a0&lt; 0.05.\n\nContribution:\u00a0The death of patients while on TB treatment needs to be addressed, including heightened advocacy for supported treatment.<\/jats:p>","DOI":"10.4102\/safp.v66i1.6004","type":"journal-article","created":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T19:07:02Z","timestamp":1729537622000},"update-policy":"https:\/\/doi.org\/10.4102\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Factors associated with unfavourable treatment outcomes among tuberculosis patients at health facilities of Maseru, Lesotho"],"prefix":"10.4102","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-1849-7282","authenticated-orcid":false,"given":"Masechaba M.","family":"Leketa","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/003hsr719","id-type":"ROR","asserted-by":"publisher"}],"name":"Sefako Makgatho Health Sciences University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6414-4327","authenticated-orcid":false,"given":"Slindile","family":"Zondi","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/003hsr719","id-type":"ROR","asserted-by":"publisher"}],"name":"Sefako Makgatho Health Sciences University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2148-7439","authenticated-orcid":false,"given":"Lindiwe","family":"Cele","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/003hsr719","id-type":"ROR","asserted-by":"publisher"}],"name":"Sefako Makgatho Health Sciences University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6493-5567","authenticated-orcid":false,"given":"Mmampedi","family":"Mathibe","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/003hsr719","id-type":"ROR","asserted-by":"publisher"}],"name":"Sefako Makgatho Health Sciences University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0523-5602","authenticated-orcid":false,"given":"Phuti","family":"Ngwepe","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03p74gp79","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Cape Town"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2580","published-online":{"date-parts":[[2024,10,21]]},"reference":[{"key":"ref0","unstructured":"World Health Organization (WHO). Global tuberculosis report 2019 [homepage on the Internet]. 2019 [cited 2021 Nov 21]. Available from: https:\/\/www.who.int\/publications\/i\/item\/9789241565714"},{"key":"ref1","unstructured":"World Health Organization (WHO). Global tuberculosis report 2020 [homepage on the Internet]. 2020 [cited 2021 Nov 21]. Available from: https:\/\/www.who.int\/publications\/i\/item\/9789240013131"},{"key":"ref2","unstructured":"World Health Organization (WHO). Global tuberculosis report 2021 [homepage on the Internet]. 2021 [cited 2021 Nov 21]. Available from: https:\/\/www.who.int\/publications\/i\/item\/9789240037021"},{"key":"ref3","unstructured":"World Health Organization (WHO). Global tuberculosis report 2018 [homepage on the Internet]. 2018 [cited 2021 Nov 21]. Available from: https:\/\/www.who.int\/publications\/i\/item\/9789241565646"},{"key":"ref4","unstructured":"CDC. Global HIV and TB: Lesotho country profile [homepage on the Internet]. 2021 [cited 2024 Feb 6]. 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