{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T18:55:20Z","timestamp":1785437720257,"version":"3.56.0"},"reference-count":29,"publisher":"AOSIS","issue":"1","license":[{"start":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T00:00:00Z","timestamp":1740700800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Background:\u00a0In Namibia, the Omuthiya Antiretroviral Therapy (ART) Clinic has indicated that nine older adolescents (15\u201319 years) out of 125 adolescents active on ART have defaulted and become lost to care. This represents an 89% retention rate among older adolescents compared to a 97% retention rate for the adult population in the same facility. There is a lack of information on the extent of ART adherence among older adolescents, particularly in terms of viral suppression rates. This study aims to measure the level of adherence to ART treatment among adolescents enrolled at the Omuthiya ART Clinic in the Oshikoto Region, Namibia.\n\nMethods:\u00a0From November to December 2020, a cross-sectional study was conducted among 100 adolescents living with HIV (ALHIV) at the Omuthiya ART Clinic. Data were collected through structured questionnaires and analysed using descriptive statistics and logistic regression.\n\nResults:\u00a0The study found that 24% of adolescent patients on ART treated at the Omuthiya ART Clinic are non-adherent to treatment. A significant association found was between education level and adherence (p\u00a0= 0.008), alcohol use and adherence (p\u00a0= 0.022) and memory aids use and adherence (p\u00a0&lt; 0.001).\n\nConclusion:\u00a0Adolescents\u2019 adherence to ART at the Omuthiya ART Clinic is influenced by educational level, alcohol use, and memory aid use. Further research is needed to explore other potential factors influencing adherence.\n\nContribution:\u00a0These findings may be used to develop ongoing strategies and targeted interventions that prioritise a patient-centred care approach, recognising the autonomy of adolescents. In addition, they highlight the importance of a supportive family environment in managing HIV and improving ART adherence.<\/jats:p>","DOI":"10.4102\/safp.v67i1.6020","type":"journal-article","created":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T08:23:31Z","timestamp":1740731011000},"update-policy":"https:\/\/doi.org\/10.4102\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Factors associated with non-adherence to antiretroviral therapy among adolescents in Oshikoto Region, Namibia"],"prefix":"10.4102","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8913-056X","authenticated-orcid":false,"given":"Daniel O.","family":"Ashipala","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/016xje988","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Namibia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3703-8906","authenticated-orcid":false,"given":"Tukwatha A.","family":"Shuukwanyama","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/016xje988","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Namibia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6075-2384","authenticated-orcid":false,"given":"Abraham V.","family":"Nghikevali","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/016xje988","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Namibia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2580","published-online":{"date-parts":[[2025,2,28]]},"reference":[{"key":"ref0","doi-asserted-by":"crossref","unstructured":"Martelli G, Antonucci R, Mukurasi A, Zepherine H, N\u00f6stlinger C. Adherence to antiretroviral treatment among children and adolescents in Tanzania: Comparison between pill count and viral load outcomes in a rural context of Mwanza region. PLoS One. 2019;14(3):e0214014. https:\/\/doi.org\/10.1371\/journal.pone.0214014","DOI":"10.1371\/journal.pone.0214014"},{"key":"ref1","unstructured":"Ministry of Health and Social Services (MoHSS). National guidelines on adolescents living with HIV. 2nd ed. Windhoek: MOHSS; 2019."},{"key":"ref2","unstructured":"Ministry of Health and Social Services (MoHSS). Namibia pediatric and adolescent HIV care and treatment strategy. Windhoek: MOHSS; 2019."},{"key":"ref3","unstructured":"Ministry of Health and Social Services (MoHSS). Namibia population-based HIV impact assessment (NAMPHIA) report. Windhoek: MOHSS; 2018."},{"key":"ref4","unstructured":"Ministry of Health and Social Services (MoHSS). HIV Quarterly Report (April to June). Omuthiya: ITECH; 2020."},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Wanjala SW, Nyongesa MK, Luchters S, Abubakar A. Psychosocial and mental health challenges facing perinatally HIV-infected adolescents along the Kenyan coast: A qualitative inquiry using the socioecological model. Front Public Health. 2024;12:1379262. https:\/\/doi.org\/10.3389\/fpubh.2024.1379262","DOI":"10.3389\/fpubh.2024.1379262"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Lowenthal ED, Bakeera-Kitaka S, Marukutira T, Chapman J, Goldrath K, Ferrand RA. Perinatally acquired HIV infection in adolescents from sub-Saharan Africa: A review of emerging challenges. Lancet Infect Dis. 2014;14(7):627\u2013639. https:\/\/doi.org\/10.1016\/S1473-3099(13)70363-3","DOI":"10.1016\/S1473-3099(13)70363-3"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Bernays S, Paparini S, Seeley J, Rhodes T. \u201cNot taking it will just be like a sin\u201d: Young people living with HIV and the stigmatization of less-than-perfect adherence to antiretroviral therapy. Med Anthropol. 2017;36(5):485\u2013499. https:\/\/doi.org\/10.1080\/01459740.2017.1306856","DOI":"10.1080\/01459740.2017.1306856"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Sohn AH, Hazra R. The changing epidemiology of the global paediatric HIV epidemic: Keeping track of perinatally HIV-infected adolescents. Afr J Reprod Gynaecolog Endosc. 2013;16(1):18555. https:\/\/doi.org\/10.7448\/IAS.16.1.18555","DOI":"10.7448\/IAS.16.1.18555"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Zanoni BC, Archary M, Buchan S, Katz IT, Haberer JE. Systematic review and meta-analysis of the adolescent HIV continuum of care in South Africa: The Cresting Wave. BMJ Glob health. 2016;1(3):e000004. https:\/\/doi.org\/10.1136\/bmjgh-2015-000004","DOI":"10.1136\/bmjgh-2015-000004"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Kim AA, Mukui I, Young PW, et al. Undisclosed HIV infection and antiretroviral therapy use in the Kenya AIDS indicator survey 2012: Relevance to national targets for HIV diagnosis and treatment. AIDS. 2016;30(17):2685\u20132695. https:\/\/doi.org\/10.1097\/QAD.0000000000001227","DOI":"10.1097\/QAD.0000000000001227"},{"key":"ref11","unstructured":"WHO. The role of HIV viral suppression in improving individual health and reducing transmission: Policy brief [homepage on the Internet]. World Health Organization; 2023 [cited 2024 Nov 28]. Available from: http:\/\/who.int\/publications\/i\/item\/9789240055179"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"Filho LFB, Nogueira SA, Machado ES, et al. Factors associated with lack of antiretroviral adherence among adolescents in a reference centre in Rio de Janeiro, Brazil. Int J STD AIDS. 2008;19(10):685\u2013688. https:\/\/doi.org\/10.1258\/ijsa.2008.008017","DOI":"10.1258\/ijsa.2008.008017"},{"key":"ref13","unstructured":"Brink H, Van der Walt C, Van Ransburg G. Fundamental of research methodology for healthcare professionals. 4th ed. Cape Town: Juta; 2018."},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"Nagata JM, Magorenge RO, Young SI, Oguta JO, Weiser SD. Social determinants, lived experiences and consequences of household food insecurity among persons living with HIV\/AIDS on the shore of Lake Victoria, Kenya. AIDS Care. 2012;24:728\u2013736. https:\/\/doi.org\/10.1080\/09540121.2011.630358","DOI":"10.1080\/09540121.2011.630358"},{"key":"ref15","unstructured":"Ministry of Health and Social Services (MoHSS). National guidelines for Antiretroviral therapy. 5th ed. Windhoek: MOHSS; 2016."},{"key":"ref16","doi-asserted-by":"crossref","unstructured":"Tiyou A, Belachew T, Alemseged F, Biadgilign S. Food insecurity and associated factors among HIV-infected individuals receiving highly active antiretroviral therapy in Jimma zone Southwest Ethiopia. Nutr J. 2012;11:51. https:\/\/doi.org\/10.1186\/1475-2891-11-51","DOI":"10.1186\/1475-2891-11-51"},{"key":"ref17","doi-asserted-by":"crossref","unstructured":"Musumari PM, Wouters E, Kayembe PK, et al. Food insecurity is associated with increased risk of non-adherence to antiretroviral therapy among HIV-infected adults in the Democratic Republic of Congo: A cross-sectional study. PLoS One. 2014;9(1):e85327. https:\/\/doi.org\/10.1371\/journal.pone.0085327","DOI":"10.1371\/journal.pone.0085327"},{"key":"ref18","doi-asserted-by":"crossref","unstructured":"Weldehaweria NB, Abreha EH, Weldu MG, Misgina KH. Psychosocial correlates of nutritional status among people living with HIV on antiretroviral therapy: A matched case-control study in Central zone of Tigray, Northern Ethiopia. PLoS One. 2017;12(3):e0174082. https:\/\/doi.org\/10.1371\/journal.pone.0174082","DOI":"10.1371\/journal.pone.0174082"},{"key":"ref19","doi-asserted-by":"crossref","unstructured":"Pellowski JA, Kalichman SC, Cherry S, et al. The daily relationship between aspects of food insecurity and medication adherence among people living with HIV with recent experiences of hunger. Ann Behav Med. 2016;50(6):844\u2013853. https:\/\/doi.org\/10.1007\/s12160-016-9812-x","DOI":"10.1007\/s12160-016-9812-x"},{"key":"ref20","doi-asserted-by":"crossref","unstructured":"Berhe N, Tegabu D, Alemayehu M. Effects of nutritional status on adherence to antiretroviral therapy among HIV-related adults: A case control study in Northern Ethiopia. BMC Infect Dis. 2013;13:233. https:\/\/doi.org\/10.1186\/1471-2334-13-233","DOI":"10.1186\/1471-2334-13-233"},{"key":"ref21","doi-asserted-by":"crossref","unstructured":"Mekuria LA, Sprangers MAG, Prins JM, Yalew AW, Nieuwkerk PT. Health related quality of life of HIV related adults receiving combination antiretroviral therapy in Addis Ababa. AIDS Care. 2015;27:934\u2013945. https:\/\/doi.org\/10.1080\/09540121.2015.1020748","DOI":"10.1080\/09540121.2015.1020748"},{"key":"ref22","doi-asserted-by":"crossref","unstructured":"MacCarthy S, Saya U, Samba C, Birungi J, Okoboi S, Linnemayr S. How am I going to live?\u201d: Exploring barriers to ART adherence among adolescents and young adults living with HIV in Uganda. BMC Public Health. 2018;18(1):1158. https:\/\/doi.org\/10.1186\/s12889-018-6048-7","DOI":"10.1186\/s12889-018-6048-7"},{"key":"ref23","doi-asserted-by":"crossref","unstructured":"Slogrove AL, Powis KM, Johnson LF, Stover J, Mahy M. Estimates of the global population of children who are HIV-exposed and uninfected, 2000\u201318: A modelling study. Lancet Glob Health. 2020;8(1):e67\u2013e75. https:\/\/doi.org\/10.1016\/S2214-109X(19)30448-6","DOI":"10.1016\/S2214-109X(19)30448-6"},{"key":"ref24","doi-asserted-by":"crossref","unstructured":"Vreeman RC, Ayaya SO, Musick BS, et al. Adherence to antiretroviral therapy in a clinical cohort of HIV-infected children in East Africa. PLoS One. 2018;13(2):e0191848. https:\/\/doi.org\/10.1371\/journal.pone.0191848","DOI":"10.1371\/journal.pone.0191848"},{"key":"ref25","doi-asserted-by":"crossref","unstructured":"Hlophe LD, Tamuzi JL, Shumba CS, Nyasulu PS. Barriers and facilitators to anti-retroviral therapy adherence among adolescents aged 10 to 19 years living with HIV in sub-Saharan Africa: A mixed-methods systematic review and meta-analysis. PLos One. 2023;18(5):e0276411. https:\/\/doi.org\/10.1371\/journal.pone.0276411","DOI":"10.1371\/journal.pone.0276411"},{"key":"ref26","doi-asserted-by":"crossref","unstructured":"Chhim K, Mburu G, Tuot S, et al. Factors associated with viral non-suppression among adolescents living with HIV in Cambodia: A cross-sectional study. AIDS Res Ther. 2018;15(1):20.","DOI":"10.1186\/s12981-018-0205-z"},{"key":"ref27","doi-asserted-by":"crossref","unstructured":"Gross R, Bandason T, Langhaug L, Mujuru H, Lowenthal E, Ferrand R. Factors associated with self-reported adherence among adolescents on antiretroviral therapy in Zimbabwe. AIDS Care. 2015;27(3):322\u2013326. https:\/\/doi.org\/10.1080\/09540121.2014.969676","DOI":"10.1080\/09540121.2014.969676"},{"key":"ref28","doi-asserted-by":"crossref","unstructured":"Altice F, Evuarherhe O, Shina S, Carter G, Beaubrun AC. Adherence to HIV treatment regimens: Systematic literature review and meta-analysis. 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