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We report the case of a young man with Lemierre\u2019s syndrome caused by\u00a0Streptococcus pyogenes, who responded well to 2 weeks of beta-lactam therapy.\n\nContributions:\u00a0This case report summarises the key presenting features of Lemierre\u2019s syndrome and provides a brief literature review considering the South African context.<\/jats:p>","DOI":"10.4102\/sajid.v39i1.606","type":"journal-article","created":{"date-parts":[[2024,4,10]],"date-time":"2024-04-10T05:31:03Z","timestamp":1712727063000},"update-policy":"https:\/\/doi.org\/10.4102\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Lemierre\u2019s syndrome: A rare complication of acute bacterial pharyngitis"],"prefix":"10.4102","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5632-722X","authenticated-orcid":false,"given":"Pierre","family":"Joubert","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03p74gp79","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Cape Town"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4354-3817","authenticated-orcid":false,"given":"Muhammed S.","family":"Moosa","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03p74gp79","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Cape Town"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2580","published-online":{"date-parts":[[2024,4,9]]},"reference":[{"key":"ref0","doi-asserted-by":"crossref","unstructured":"Lemierre A. On certain septicaemias due to anaerobic organisms. Lancet. 1936;227(5874):701\u2013703. https:\/\/doi.org\/10.1016\/S0140-6736(00)57035-4","DOI":"10.1016\/S0140-6736(00)57035-4"},{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Gore MR. Lemierre syndrome: A Meta-analysis. Int Arch Otorhinolaryngol. 2020;24(3):379\u2013385. https:\/\/doi.org\/10.1055\/s-0039-3402433","DOI":"10.1055\/s-0039-3402433"},{"key":"ref2","unstructured":"Allen BW, Anjum F, Bentley TP. Lemierre syndrome [homepage on the Internet]. Treasure Island, FL: StatPearls Publishing; 2023 [cited 2023 Jun 10]. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK499846\/"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Bank S, Jensen A, Nielsen HM, Kristensen LH, Voldstedlund M, Prag J. Fusobacterium necrophorum findings in Denmark from 2010 to 2014 using data from the Danish microbiology database. J Pathol Microbiol Immunol. 2016;124(12):1087\u20131092. https:\/\/doi.org\/10.1111\/apm.12606","DOI":"10.1111\/apm.12606"},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"Lee W Sen, Jean SS, Chen FL, Hsieh SM, Hsueh PR. Lemierre\u2019s syndrome: A forgotten and re-emerging infection. J Microbiol Immunol Infect. 2020;53(4):513\u2013517. https:\/\/doi.org\/10.1016\/j.jmii.2020.03.027","DOI":"10.1016\/j.jmii.2020.03.027"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Roos M, Harris T, Seedat R. Fatal lemierre\u2019s syndrome as a complication of chronic otitis media with cholesteatoma. S Afr J Child Health. 2016;10(4):231\u2013232. https:\/\/doi.org\/10.7196\/SAJCH.2016.v10i4.1074","DOI":"10.7196\/SAJCH.2016.v10i4.1074"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Amarnani S, Ranjan A. Lemierre\u2019s syndrome: A lethal complication of acute tonsillitis. Cureus. 2022;14(10):8\u201313. https:\/\/doi.org\/10.7759\/cureus.30072","DOI":"10.7759\/cureus.30072"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Such R, Joseph E. Lemierre\u2019s syndrome \u2013 The uncommon cold. S Afr J Radiol. 2005;9(2):22. https:\/\/doi.org\/10.4102\/sajr.v9i2.87","DOI":"10.4102\/sajr.v9i2.87"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Olivier JB, Al-Hourani K, Bolland B. Lemierre\u2019s syndrome; a rare cause of septic arthritis. BMJ Case Rep. 2017;2017:1\u20134. https:\/\/doi.org\/10.1136\/bcr-2017-220110","DOI":"10.1136\/bcr-2017-220110"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Moher D, Liberati A, Tetzlaff J, et al. Lemierre\u2019s syndrome: Current perspectives on diagnosis and management. Infect Drug Resist. 2016;9(7):221\u2013227.","DOI":"10.2147\/IDR.S95050"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Chaker K, Berrada O, Lyoubi M, et al. Lemierre\u2019s syndrome or re-emerging disease: Case report and literature review. Int J Surg Case Rep. 2021;78:151\u2013154. https:\/\/doi.org\/10.1016\/j.ijscr.2020.12.015","DOI":"10.1016\/j.ijscr.2020.12.015"},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"Hwang SY, Shin SJ, Yoon HE. Lemierre\u2019s syndrome caused by Klebsiella pneumoniae: A case report. World J Nephrol. 2021;10(5):101\u2013108. https:\/\/doi.org\/10.5527\/wjn.v10.i5.101","DOI":"10.5527\/wjn.v10.i5.101"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"Kebede D, Admas A, Mekonnen D. Prevalence and antibiotics susceptibility profiles of Streptococcus pyogenes among pediatric patients with acute pharyngitis at Felege Hiwot Comprehensive Specialized Hospital, Northwest Ethiopia. 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