{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:47:37Z","timestamp":1787168857026,"version":"build-2736575974"},"reference-count":0,"publisher":"AOSIS","issue":"1","license":[{"start":{"date-parts":[[2021,11,10]],"date-time":"2021-11-10T00:00:00Z","timestamp":1636502400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["S. Afr. j. radiol."],"abstract":"<jats:p>Positron emission tomography combined with X-ray computed tomography (PET-CT) has an established role in the management of brain disorders, but may be underutilised in South Africa. Possible barriers to access include the limited number of PET-CT facilities and the lack of contemporary guidelines for the use of brain PET-CT in South Africa. The current review aims to highlight the evidence-based usage of brain Positron emission tomography (PET) in dementia, movement disorders, brain tumours, epilepsy, neuropsychiatric lupus, immune-mediated encephalitides, and brain infections. While being areas of research, there is currently no clinical role for the use of PET-CT in traumatic brain injury or in psychiatric or neurodevelopmental disorders. Strategies to expand the appropriate use of PET-CT in brain disorders are discussed in this article.<\/jats:p>","DOI":"10.4102\/sajr.v25i1.2201","type":"journal-article","created":{"date-parts":[[2021,11,11]],"date-time":"2021-11-11T04:04:25Z","timestamp":1636603465000},"source":"Crossref","is-referenced-by-count":5,"title":["PET-CT in brain disorders: The South African context"],"prefix":"10.4102","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9294-1737","authenticated-orcid":false,"given":"Alexander G.G.","family":"Doruyter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7735-1111","authenticated-orcid":false,"given":"Jeannette","family":"Parkes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7677-426X","authenticated-orcid":false,"given":"Jonathan","family":"Carr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2810-0543","authenticated-orcid":false,"given":"James M.","family":"Warwick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2580","published-online":{"date-parts":[[2021,11,10]]},"container-title":["South African Journal of Radiology"],"original-title":[],"link":[{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/viewFile\/2201\/3009","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/viewFile\/2201\/3010","content-type":"application\/epub+zip","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/viewFile\/2201\/3012","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/viewFile\/2201\/3013","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/viewFile\/2201\/3013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,11]],"date-time":"2021-11-11T04:04:26Z","timestamp":1636603466000},"score":1,"resource":{"primary":{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/view\/2201"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,10]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,1,15]]}},"URL":"https:\/\/doi.org\/10.4102\/sajr.v25i1.2201","relation":{},"ISSN":["2078-6778","1027-202X"],"issn-type":[{"value":"2078-6778","type":"electronic"},{"value":"1027-202X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11,10]]}}}