{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T06:04:35Z","timestamp":1774591475605,"version":"3.50.1"},"reference-count":0,"publisher":"AOSIS","issue":"1","license":[{"start":{"date-parts":[[2022,10,26]],"date-time":"2022-10-26T00:00:00Z","timestamp":1666742400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["S. Afr. j. radiol."],"abstract":"<jats:p>Background:\u00a0Meningiomas are the most prevalent of all intracranial tumours. Although they are mostly benign, about 20% of meningiomas are atypical or malignant. Knowledge of their histologic grade can be clinically useful while planning surgery.Objectives:\u00a0To differentiate between various grades and subtypes of meningiomas with advanced MR parameters.Method:\u00a0We assessed the advanced MR imaging characteristics of 27 histopathologically confirmed meningiomas on a 3T MRI, of which 23 were grade I meningiomas (2 fibroblastic, 9 meningothelial, 9 transitional, 3 unspecified) and 4 were grade II\/III meningiomas (2 atypical, 1 papillary, 1 anaplastic). Analysis of the ADC, FA, \u03bb1, \u03bb2, \u03bb3 and mean diffusivity was performed using standard post-processing software.Results:\u00a0The mean size of atypical meningiomas (5.9 cm \u00b1 0.7 cm) was significantly higher (p\u00a0= 0.038, 95% confidence interval [CI]) than that of typical meningiomas (4.6 cm \u00b1 1.6 cm) with a cut-off value of 6.05 cm (75% sensitivity and 87% specificity). The mean cerebral blood flow (CBF) (ASL) of atypical meningiomas (286.70 \u00b1 8.06) was significantly higher (p\u00a0= 0.0000141, 95% CI) than that of typical meningiomas (161.09 \u00b1 87.04) with a cut-off value of 276.75 (66.7% sensitivity and 75% specificity). Among the typical meningiomas, transitional subtypes had the lowest ADC. High FA and planar coefficient (CP) values and low \u03bb3 and spherical coefficient (CS) values were seen in fibroblastic meningiomas. Fibroblastic meningiomas also showed the lowest vascularity among typical meningiomas.Conclusion:\u00a0Tumour size and ASL perfusion are two parameters that could differentiate between typical and atypical meningiomas while ADC, FA, \u03bb3, CP, CS, rCBF and rCBV may be helpful in distinguishing different subtypes of typical meningiomas.<\/jats:p>","DOI":"10.4102\/sajr.v26i1.2480","type":"journal-article","created":{"date-parts":[[2022,11,3]],"date-time":"2022-11-03T07:53:43Z","timestamp":1667462023000},"source":"Crossref","is-referenced-by-count":5,"title":["Differentiation between various types and subtypes of intracranial meningiomas with advanced MRI"],"prefix":"10.4102","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3891-6842","authenticated-orcid":false,"given":"Mousam","family":"Panigrahi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1736-3329","authenticated-orcid":false,"given":"Narendra K.","family":"Bodhey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9120-5452","authenticated-orcid":false,"given":"Saroj K.","family":"Pati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1120-2452","authenticated-orcid":false,"given":"Nighat","family":"Hussain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2974-9720","authenticated-orcid":false,"given":"Anil K.","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8336-6830","authenticated-orcid":false,"given":"Arvind K.","family":"Shukla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2580","published-online":{"date-parts":[[2022,10,26]]},"container-title":["South African Journal of Radiology"],"original-title":[],"link":[{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/viewFile\/2480\/3270","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/viewFile\/2480\/3271","content-type":"application\/epub+zip","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/viewFile\/2480\/3272","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/viewFile\/2480\/3273","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/viewFile\/2480\/3273","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,3]],"date-time":"2022-11-03T07:53:43Z","timestamp":1667462023000},"score":1,"resource":{"primary":{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/view\/2480"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,26]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,1,11]]}},"URL":"https:\/\/doi.org\/10.4102\/sajr.v26i1.2480","relation":{},"ISSN":["2078-6778","1027-202X"],"issn-type":[{"value":"2078-6778","type":"electronic"},{"value":"1027-202X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10,26]]}}}