{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T13:10:07Z","timestamp":1745327407255,"version":"3.40.4"},"reference-count":28,"publisher":"AOSIS","issue":"1","license":[{"start":{"date-parts":[[2023,12,26]],"date-time":"2023-12-26T00:00:00Z","timestamp":1703548800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"DOI":"10.4102\/sajr.v27i1.2728","type":"journal-article","created":{"date-parts":[[2023,12,26]],"date-time":"2023-12-26T11:33:57Z","timestamp":1703590437000},"source":"Crossref","is-referenced-by-count":1,"title":["Neuroquantification enhances the radiological evaluation of term neonatal hypoxic-ischaemic cerebral injuries"],"prefix":"10.4102","volume":"27","author":[{"given":"Shalendra K.","family":"Misser","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuhle","family":"Mchunu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan W.","family":"Lotz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Kjonigsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aziz","family":"Ulug","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moherndran","family":"Archary","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2580","published-online":{"date-parts":[[2023,12,26]]},"reference":[{"key":"ref0","unstructured":"Volpe JJ. Neurology of the newborn. 6th ed. Philadelphia, PA: Saunders; 2018, Chapter 18 and 19."},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"Nanyunja C, Sadoo S, Mambule I, et al. Protocol for the Birth Asphyxia in African Newborns (Baby BRAiN) Study: A Neonatal Encephalopathy Feasibility Cohort Study [version 1; peer review: 2 approved]. Gates Open Res. 2022;6:10. https:\/\/doi.org\/10.12688\/gatesopenres.13557.1","DOI":"10.12688\/gatesopenres.13557.1"},{"key":"ref2","unstructured":"Barkovich AJ, Truwit CL. Brain damage from perinatal asphyxia: Correlation of MR findings with gestational age. AJNR Am J Neuroradiol. 1990;11:1087-1096."},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"Rutherford M, Malamateniou C, McGuinness A, Allsop J, Biarge MM, Counsell S. Magnetic resonance imaging in hypoxic-ischaemic encephalopathy. Early Hum Dev. 2010;86(6):351-360. https:\/\/doi.org\/10.1016\/j.earlhumdev.2010.05.014","DOI":"10.1016\/j.earlhumdev.2010.05.014"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"De Vries LS, Groenendaal F. Patterns of neonatal hypoxic-ischaemic brain injury. Neuroradiology. 2010;52(6):555-566. https:\/\/doi.org\/10.1007\/s00234-010-0674-9","DOI":"10.1007\/s00234-010-0674-9"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"Miller SP, Ramaswamy V, Michelson D, et al. Patterns of brain injury in term neonatal encephalopathy. J Pediatr. 2005;146(4):453-460. https:\/\/doi.org\/10.1016\/j.jpeds.2004.12.026","DOI":"10.1016\/j.jpeds.2004.12.026"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"Sie L, Van der Knaap M, Oosting J, De Vries L, Lafeber H, Valk J. MR patterns of hypoxic-ischemic brain damage after prenatal, perinatal or postnatal asphyxia. Neuropediatrics. 2000;31(03):128-136. https:\/\/doi.org\/10.1055\/s-2000-7496","DOI":"10.1055\/s-2000-7496"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"Ranck JB, Windle WF. Brain damage in the monkey, macaca mulatta, by asphyxia neonatorum. Exp Neurol 1959;1(2):131-150. https:\/\/doi.org\/10.1016\/0014-4886(59)90032-9","DOI":"10.1016\/0014-4886(59)90032-9"},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"Mota-Rojas D, Villanueva-Garc\u00eda D, Solimano A, Muns R, Ibarra-R\u00edos D, Mota-Reyes A. Pathophysiology of perinatal asphyxia in humans and animal models. Biomedicines. 2022;10(2):347. https:\/\/doi.org\/10.3390\/biomedicines10020347","DOI":"10.3390\/biomedicines10020347"},{"key":"ref9","doi-asserted-by":"publisher","unstructured":"Windle WF. Brain damage at birth. JAMA. 1968;206;1967. https:\/\/doi.org\/10.1001\/jama.206.9.1967","DOI":"10.1001\/jama.206.9.1967"},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"Myers RE. Two patterns of perinatal brain damage and their conditions of occurrence. Am J Obstet Gynecol. 1972;112(2):246-276. https:\/\/doi.org\/10.1016\/0002-9378(72)90124-X","DOI":"10.1016\/0002-9378(72)90124-X"},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"Gunn AJ, Bennet L. Fetal hypoxia insults and patterns of brain injury: insights from animal models. Clin Perinatol. 2009;36(3):579-593. https:\/\/doi.org\/10.1016\/j.clp.2009.06.007","DOI":"10.1016\/j.clp.2009.06.007"},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"Lai MC, Yang SN. Perinatal hypoxic-ischemic encephalopathy. J Biomed Biotechnol 2011;2011:609813. https:\/\/doi.org\/10.1155\/2011\/609813","DOI":"10.1155\/2011\/609813"},{"key":"ref13","doi-asserted-by":"publisher","unstructured":"Misser SK, Barkovich AJ, Lotz JW, Archary M. A pictorial review of the pathophysiology and classification of the magnetic resonance imaging patterns of perinatal term hypoxic ischemic brain injury - What the radiologist needs to know\u2026 S Afr J Radiol. 2020;24(1):1915. https:\/\/doi.org\/10.4102\/sajr.v24i1.1915","DOI":"10.4102\/sajr.v24i1.1915"},{"key":"ref14","doi-asserted-by":"publisher","unstructured":"Pringle C, Kilday JP, Kamaly-Asl I, Stivaros SM. The role of artificial intelligence in paediatric neuroradiology. Pediatr Radiol. 2022;52(11):2159-2172. https:\/\/doi.org\/10.1007\/s00247-022-05322-w","DOI":"10.1007\/s00247-022-05322-w"},{"key":"ref15","doi-asserted-by":"publisher","unstructured":"Iwasaki N, Hamano K, Okada Y, et al. Volumetric quantification of brain development using MRI. Neuroradiology. 1997;39(12):841-846. https:\/\/doi.org\/10.1007\/s002340050517","DOI":"10.1007\/s002340050517"},{"key":"ref16","doi-asserted-by":"publisher","unstructured":"Reid LB, Pagnozzi AM, Fiori S, Boyd RN, Dowson N, Rose SE. Measuring neuroplasticity associated with cerebral palsy rehabilitation: An MRI based power analysis. Int J Dev Neurosci. 2017;58:17-25. https:\/\/doi.org\/10.1016\/j.ijdevneu.2017.01.010","DOI":"10.1016\/j.ijdevneu.2017.01.010"},{"key":"ref17","doi-asserted-by":"publisher","unstructured":"Faria AV, Hoon A, Stashinko E, et al. Quantitative analysis of brain pathology based on MRI and brain atlases-Applications for cerebral palsy. NeuroImage. 2011;54(3):1854-1861. https:\/\/doi.org\/10.1016\/j.neuroimage.2010.09.061","DOI":"10.1016\/j.neuroimage.2010.09.061"},{"key":"ref18","doi-asserted-by":"publisher","unstructured":"Misser SK, Lotz JW, Zaharie SD, et al. A proposed magnetic resonance imaging grading system for the spectrum of central neonatal parasagittal hypoxic-ischaemic brain injury. Insights Imaging. 2022;13:11. https:\/\/doi.org\/10.1186\/s13244-021-01139-7","DOI":"10.1186\/s13244-021-01139-7"},{"key":"ref19","doi-asserted-by":"publisher","unstructured":"Chacko A, Andronikou S, Mian A, et al. Cortical ischaemic patterns in term partial-prolonged hypoxic-ischaemic injury - The inter-arterial watershed demonstrated through atrophy, ulegyria and signal change on delayed MRI scans in children with cerebral palsy. Insights Imaging. 2020;11(1):53. https:\/\/doi.org\/10.1186\/s13244-020-00857-8","DOI":"10.1186\/s13244-020-00857-8"},{"key":"ref20","doi-asserted-by":"publisher","unstructured":"Misser SK, Lotz JW, Van Toorn R, Mchunu N, Archary M, Barkovich AJ. Thalamus L-sign: A potential biomarker of neonatal partial, prolonged hypoxic-ischemic brain injury or hypoglycemic encephalopathy? AJNR Am J Neuroradiol. 2022;43(6):919-925. https:\/\/doi.org\/10.3174\/ajnr.A7511","DOI":"10.3174\/ajnr.A7511"},{"key":"ref21","doi-asserted-by":"publisher","unstructured":"De Vries LS, Jongmans MJ. Long-term outcome after neonatal hypoxic-ischaemic encephalopathy. Arch Dis Child Fetal Neonatal Ed. 2010;95(3):F220-F224. https:\/\/doi.org\/10.1136\/adc.2008.148205","DOI":"10.1136\/adc.2008.148205"},{"key":"ref22","doi-asserted-by":"publisher","unstructured":"Pagnozzi AM, Gal Y, Boyd RN, et al. The need for improved brain lesion segmentation techniques for children with cerebral palsy: A review. Int J Dev Neurosci. 2015;47(Part B):229-246. https:\/\/doi.org\/10.1016\/j.ijdevneu.2015.08.004","DOI":"10.1016\/j.ijdevneu.2015.08.004"},{"key":"ref23","doi-asserted-by":"publisher","unstructured":"Quattrocchi CC, Errante Y, Rossi Espagnet MC, et al. Magnetic resonance imaging differential diagnosis of brainstem lesions in children. World J Radiol. 2016;8(1):1-20. https:\/\/doi.org\/10.4329\/wjr.v8.i1.1","DOI":"10.4329\/wjr.v8.i1.1"},{"key":"ref24","doi-asserted-by":"publisher","unstructured":"Elsingergy MM, Worede F, Venkatakrishna S, Andronikou S. Deep nuclei injury distribution in isolated \"basal ganglia-thalamus\" (BGT) versus combined \"BGT and watershed\" patterns of hypoxic-ischaemic injury (HII) in children with cerebral palsy. Clin Radiol. 2022;77(11):825-832. https:\/\/doi.org\/10.1016\/j.crad.2022.04.019","DOI":"10.1016\/j.crad.2022.04.019"},{"key":"ref25","doi-asserted-by":"publisher","unstructured":"Stivaros SM, Radon MR, Mileva R, et al. Quantification of structural changes in the corpus callosum in children with profound hypoxic-ischaemic brain injury. Pediatr Radiol. 2016;46(1):73-81. https:\/\/doi.org\/10.1007\/s00247-015-3444-3","DOI":"10.1007\/s00247-015-3444-3"},{"key":"ref26","doi-asserted-by":"publisher","unstructured":"Andronikou S, Pillay T, Gabuza L, et al. Corpus callosum thickness in children: An MR pattern-recognition approach on the midsagittal image. Pediatr Radiol. 2015;45(2):258-272. https:\/\/doi.org\/10.1007\/s00247-014-2998-9","DOI":"10.1007\/s00247-014-2998-9"},{"key":"ref27","doi-asserted-by":"publisher","unstructured":"Garhwal A, Patil A. Role of magnetic resonance imaging in biometric evaluation of corpus callosum in hypoxic ischemic encephalopathy patients. J Sci Soc. 2017;44(2):67-75. https:\/\/doi.org\/10.4103\/jss.JSS_30_16","DOI":"10.4103\/jss.JSS_30_16"}],"container-title":["South African Journal of Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/viewFile\/2728\/3524","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/viewFile\/2728\/3525","content-type":"application\/epub+zip","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/viewFile\/2728\/3526","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/viewFile\/2728\/3527","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/viewFile\/2728\/3527","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T12:42:43Z","timestamp":1745325763000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.sajr.org.za\/index.php\/SAJR\/article\/view\/2728"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,26]]},"references-count":28,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,12,26]]}},"URL":"https:\/\/doi.org\/10.4102\/sajr.v27i1.2728","relation":{},"ISSN":["2078-6778","1027-202X"],"issn-type":[{"type":"electronic","value":"2078-6778"},{"type":"print","value":"1027-202X"}],"subject":[],"published":{"date-parts":[[2023,12,26]]}}}