{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T13:01:29Z","timestamp":1790168489702,"version":"4.1.0"},"reference-count":21,"publisher":"AOSIS","issue":"1","license":[{"start":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T00:00:00Z","timestamp":1716422400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Fibrous dysplasia (FD) is a rare, non-inherited, congenital bone disorder which may be monostotic or polyostotic. The polyostotic form may rarely present in syndromic forms when associated with extra-skeletal manifestations. Mazabraud syndrome is a rare syndrome consisting of polyostotic FD presenting with intramuscular myxomas. McCune\u2013Albright syndrome is recognised by polyostotic FD, precocious puberty and \u2018caf\u00e9 au lait\u2019 spots. This report describes an adult patient with Mazabraud syndrome and a child with McCune\u2013Albright syndrome.\n\nContribution:\u00a0Radiographic findings are typical with bowing deformities, sclerotic, lucent or mixed lesions and bony expansion, often with endosteal scalloping. MRI is often non-contributory and may actually mimic a more aggressive process. Early detection and correct diagnosis allow for early preventative treatment and rehabilitation to prevent devastating neurological sequelae and disability.<\/jats:p>","DOI":"10.4102\/sajr.v28i1.2877","type":"journal-article","created":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T07:14:26Z","timestamp":1716448466000},"update-policy":"https:\/\/doi.org\/10.4102\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Fibrous dysplasia: A tale of two syndromes"],"prefix":"10.4102","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-6024-9978","authenticated-orcid":false,"given":"Jacques","family":"Fourie","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00g0p6g84","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Pretoria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5097-2092","authenticated-orcid":false,"given":"Farhana","family":"Suleman","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00g0p6g84","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Pretoria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4797-4622","authenticated-orcid":false,"given":"Zarina","family":"Lockhat","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00g0p6g84","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Pretoria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2601-7196","authenticated-orcid":false,"given":"Kumeshnie","family":"Kollapen","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00g0p6g84","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Pretoria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2580","published-online":{"date-parts":[[2024,5,23]]},"reference":[{"key":"ref0","doi-asserted-by":"crossref","unstructured":"Seabra Rato M, Bernardo A, Oliveira Pinheiro F, Bernardes M, Costa L. 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