{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T14:32:26Z","timestamp":1791469946726,"version":"4.3.4"},"reference-count":10,"publisher":"AOSIS","issue":"1","license":[{"start":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T00:00:00Z","timestamp":1745884800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Nerve sheath tumours of the sympathetic chain are extremely rare and present a diagnostic challenge. A 42-year-old female presented with asymptomatic left cervical swelling. Imaging with sonography, CT, MR and angiography demonstrated a lesion splaying the carotid bifurcation, the lyre sign. Following surgical excision, histology revealed a schwannoma. Imaging features of carotid body tumours and parapharyngeal schwannomas can be similar, as both can cause splaying of the carotid bifurcation. The differential diagnosis of such tumours and their management are discussed.\n\nContribution: This article highlights another cause of the lyre sign on radiological imaging besides carotid body tumours.<\/jats:p>","DOI":"10.4102\/sajr.v29i1.3072","type":"journal-article","created":{"date-parts":[[2025,4,26]],"date-time":"2025-04-26T09:34:33Z","timestamp":1745660073000},"update-policy":"https:\/\/doi.org\/10.4102\/crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["Lyre sign \u2013 Where schwannoma mimics a carotid body tumour"],"prefix":"10.4102","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-1133-0439","authenticated-orcid":false,"given":"Fatin N.","family":"Sahar","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05n8tts92","id-type":"ROR","asserted-by":"publisher"}],"name":"Universiti Teknologi MARA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4057-0000","authenticated-orcid":false,"given":"Hilwati","family":"Hashim","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05n8tts92","id-type":"ROR","asserted-by":"publisher"}],"name":"Universiti Teknologi MARA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3160-6043","authenticated-orcid":false,"given":"Norliana D.","family":"Mohamad Ali","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05n8tts92","id-type":"ROR","asserted-by":"publisher"}],"name":"Universiti Teknologi MARA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0435-8985","authenticated-orcid":false,"given":"Masaany","family":"Mansor","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05n8tts92","id-type":"ROR","asserted-by":"publisher"}],"name":"Universiti Teknologi MARA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4897-9927","authenticated-orcid":false,"given":"Yin P.","family":"Wong","sequence":"additional","affiliation":[{"name":"Universiti Kebangsaan Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2580","published-online":{"date-parts":[[2025,4,29]]},"reference":[{"key":"ref0","doi-asserted-by":"crossref","unstructured":"Gopinathan A, Tan TY. Imaging characteristics of Schwannoma of the cervical sympathetic chain: A review of 12 cases. Am J Neuroradiol. 2010;31(8):1408\u20131412. https:\/\/doi.org\/10.3174\/ajnr.a2212","DOI":"10.3174\/ajnr.A2212"},{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Itawi S, Buehler M, Mrak RE, Mansour TR, Medhkour Y, Medhkour A. A unique case of carotid splaying by a cervical vagal neurofibroma and the role of neuroradiology in surgical management. Cureus. 2017;9(9):e1658. https:\/\/doi.org\/10.7759\/cureus.1658","DOI":"10.7759\/cureus.1658"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Loperfido A, Celebrini A, Fionda B, Bellocchi G, Cristalli G. Diagnostic and therapeutic strategy for vagal schwannoma: Case series and literature review. Medicina-lithuania. 2023;59(6):1013. https:\/\/doi.org\/10.3390\/medicina59061013","DOI":"10.3390\/medicina59061013"},{"key":"ref3","unstructured":"Neural Crest Cell Tumors (PNT = peripheral neuroblastic tumors). 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Am J Pathol. 1982;106(2):261\u2013268."},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Hoang VT, Trinh CT, Lai TAK, Doan DT, Tran TTT. Carotid body tumor: A case report and literature review [Review of Carotid body tumor: A case report and literature review]. J Radiol Case Rep. 2019;13(8):19. https:\/\/doi.org\/10.3941\/jrcr.v13i8.3681","DOI":"10.3941\/jrcr.v13i8.3681"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Varoquaux A, Fakhry N, Gabriel S, et al. Retrostyloid parapharyngeal space tumors: A clinician and imaging perspective. Eur J Radiol. 2013;82(5):773\u2013782. https:\/\/doi.org\/10.1016\/j.ejrad.2013.01.005","DOI":"10.1016\/j.ejrad.2013.01.005"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Lee MK, Sidell DR, Mendelsohn AH, Blackwell KE. Hypoglossal schwannoma masquerading as a carotid body tumor. Case Rep Otolaryngol. 2012;2012:1\u20134. https:\/\/doi.org\/10.1155\/2012\/842761","DOI":"10.1155\/2012\/842761"}],"container-title":["South African Journal of Radiology"],"original-title":[],"link":[{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/view\/3072\/3819","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T10:40:18Z","timestamp":1748947218000},"score":1,"resource":{"primary":{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/view\/3072"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,29]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,1,1]]}},"URL":"https:\/\/doi.org\/10.4102\/sajr.v29i1.3072","relation":{},"ISSN":["1027-202X","2078-6778"],"issn-type":[{"value":"1027-202X","type":"print"},{"value":"2078-6778","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,29]]},"article-number":"a3072"}}